Incorporating Non-Coding Annotations into Rare Variant Analysis. by Tom G Richardson, Colin Campbell, Nicholas J Timpson, Tom R Gaunt

“…<h4>Methods & results</h4>We conducted a candidate gene analysis using the UK10K sequence and lipids data, filtering according to functional annotations using the resource CADD (Combined Annotation-Dependent Depletion) and contrasting results with 'nonsynonymous' and 'loss of function' consequence analyses. …”
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TOP: A Combined Logical and Physical Obfuscation Method for Securing Networks-on-Chip Against Reverse Engineering Attacks by Mona Hashemi, Siamak Mohammadi, Trevor E. Carlson

“…First, our centralized approach combines power-gating and structure obfuscation, ensuring efficiency and scalability to corrupt the function and traffic pattern of the network when an incorrect key is presented. …”
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A mixed-method approach to develop an eco-robust supply chain management framework for Bangladeshi RMG industries by Md Al Amin, Roberto Baldacci

“…The methodology employs a mixed-method approach: expert insights were collected and prioritized using the Analytical Hierarchy Process to rank ERSCM strategies, which were then mapped to sustainability and resilience goals through Quality Function Deployment. This relationship analysis was followed by a Mixed-Integer Linear Programming optimization to select cost-effective strategies that maximize eco-robust performance under budget constraints. …”
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Toward Sustainable Agriculture: DPA-UNet for Semantic Segmentation of Landscapes Using Remote Sensing Imagery by J. Kavipriya, G. Vadivu

“…Particularly in agricultural contexts where exact delineation of land cover types is vital for resource management and planning, semantic segmentation is a key technique for high-resolution image interpretation. …”
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Effects of climate change on goat production and mitigatory measures in semiarid savanna ecosystems by Alban Mugoti, Casper Nyamukanza, Anderson Munengwa, Sizo Moyo, Nation Chikumba

“…Climate change negatively affects goat productivity through decreased availability of high-quality forage, impaired reproductive function due to heat stress, and increased incidence of diseases associated with changing weather patterns. …”
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Digital Twin-Based Technical Research on Comprehensive Gear Fault Diagnosis and Structural Performance Evaluation by Qiang Zhang, Zhe Wu, Boshuo An, Ruitian Sun, Yanping Cui

“…The advantage of the research lies in the interaction and visualization of fusion of multi-source data, but it is limited to the accuracy of finite element simulation and the difficulty of obtaining actual stress data. …”
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Unveiling smart contract vulnerabilities: Toward profiling smart contract vulnerabilities using enhanced genetic algorithm and generating benchmark dataset by Sepideh HajiHosseinKhani, Arash Habibi Lashkari, Ali Mizani Oskui

“…This dataset consists of 111,897 Solidity source code samples, ensuring the practical validation of the proposed approach. …”
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Impulse Shaping Method Based on Bayesian Deconvolution by JIA Tonghui, LIU Yi, WANG Ming, MA Yingjie, WANG Bo

“…The initial step of this method entailed expressing the measured pulse signal as the convolution of the current impulse pulse signal and the detection system response function. Then, the measured signal was expressed in the continuous time domain and decomposed into the form of an impulse signal and a double exponential kernel convolution by derivation. …”
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Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression by Marco Bolis, Daniela Bossi, Arianna Vallerga, Valentina Ceserani, Manuela Cavalli, Daniela Impellizzieri, Laura Di Rito, Eugenio Zoni, Simone Mosole, Angela Rita Elia, Andrea Rinaldi, Ricardo Pereira Mestre, Eugenia D’Antonio, Matteo Ferrari, Flavio Stoffel, Fernando Jermini, Silke Gillessen, Lukas Bubendorf, Peter Schraml, Arianna Calcinotto, Eva Corey, Holger Moch, Martin Spahn, George Thalmann, Marianna Kruithof-de Julio, Mark A. Rubin, Jean-Philippe P. Theurillat

“…Using patient-derived xenograft models, we functionally validate our observations and add single-cell resolution. …”
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Chromosome-level genome sequencing and assembly of the parasitoid wasp Leptopilina myrica by Zhi Dong, Zixuan Xu, Junwei Zhang, Yulong Guo, Qichao Zhang, Lan Pang, Ting Feng, Wenqi Shi, Yifeng Sheng, Jianhua Huang, Jiani Chen

“…Despite their ecological significance, the genomic basis of host selection and parasitism in this genus remains underexplored. …”
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Quality and content evaluation of thyroid eye disease treatment information on TikTok and Bilibili by Haisheng Wang, Huahong Zhang, Jiamin Cao, Feng Zhang, Wei Xiong

“…Abstract Thyroid eye disease (TED) is an autoimmune condition that commonly impacts patients’ visual function, appearance, and psychological well-being. …”
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The classical-to-quantum crossover in the strain-induced ferroelectric transition in SrTiO3 membranes by Jiarui Li, Yonghun Lee, Yongseong Choi, Jong-Woo Kim, Paul Thompson, Kevin J. Crust, Ruijuan Xu, Harold Y. Hwang, Philip J. Ryan, Wei-Sheng Lee

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Implementation strategies: lessons learned during an e-learning intervention to improve dietary behaviors and feeding practices in early childhood education and care by Henrik Lian, Nina Cecilie Øverby, Frøydis Nordgård Vik, Anine Christine Medin, Natalie Garzon Osorio, Christine Helle, Tormod Bjørkkjær, Penelope Love, Harry Rutter, Mary Elizabeth Barker, Elisabet Rudjord Hillesund, Sissel Heidi Helland

“…This study explores ECEC staff views and experiences with selected strategies for implementing an e-learning resource in ECEC centers in a municipality in Southern Norway. …”
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Routing algorithm for heterogeneous computing force requests based on computing first network by ZHANG Gang, LI Xi

“…By constructing a solution matrix and utilizing evaluation functions, random selection of feasible solutions, and the principle of low demand priority avoidance, a set of feasible solution sets was ultimately found. …”
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The MinDag app for symptom monitoring and feedback to patients and clinicians during the initial treatment of bipolar disorder – a feasibility study by Margrethe Collier Høegh, Stine Holmstul Glastad, Siv Hege Lyngstad, Magnus Johan Engen, Sofie Ragnhild Aminoff, Ingrid Melle, Thomas Bjella, Trine Vik Lagerberg

“…Development of digital tools to support the treatment of bipolar disorder and other mental health conditions is resource demanding, and there is a need to clarify criteria to establish proof of concept to guide the selection of tools for upscaling and implementation.…”
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Exome analysis reveals species divergence in TYR and identifies species genetic markers in five endemic Macaca species on Sulawesi Island by Xiaochan Yan, Nami Arakawa, Kanthi Arum Widayati, Laurentia Henrieta Permita Sari Purba, Fahri Fahri, Bambang Suryobroto, Yohey Terai, Hiroo Imai

“…Additionally, it explores how these genetic differences influence biological functions, and identifies species-specific genetic markers for species identification and conservation. …”
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A system for generating chatbots to support learning in the field of exact sciences using generative artificial intelligence models by Oleksandr Prokhorov, Dmytro Shymko, Olena Kuzminska, Andrey Chukhray, Oleksii Shatalov, Oleksandr Kholodniak

“…The objectives include: analyzing the challenges and peculiarities of creating chatbots and preparing high-quality datasets; developing the structure and describing the functionality of the chatbot generation system; providing examples of creating various types of chatbots; conducting experiments to determine the effectiveness and cost of chatbot generation. …”
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Synovial cesys in children: clinical features, diagnostics, treatment (analytical review of the literature and own observation) by V.S. Konoplitskyi, Yu. Ye. Korobko, B.L. Pavlenko, H.M. Rudenko, O.A. Korobko, S.V. Klymenko

“…Thus, according to literature sources, the frequency of pathology in patients under 20 years of age reaches 10% in the population and less than 2% in children under 10 years of age. …”
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Soil microbial networks’ complexity as a primary driver of multifunctionality in photovoltaic power plants in the northwest region of China by Liuqing Zhao, Sumeng Xu, Sumeng Xu, Jinmei Zhao, Shujuan Chen, Xiaolong Liu, Xiuyuan Zheng, Xiuhui Wang, Zhao Zhu, Fei Gao, Bingzhe Fu, Shuxia Li

“…IntroductionExploiting photovoltaic power generation as a novel source of clean energy has become increasingly common in recent times. …”
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Seeing Beyond Noise: Improving Cryptocurrency Forecasting with Linear Bias Correction by Sibtain Syed, Syed Muhammad Talha, Arshad Iqbal, Naveed Ahmad, Mohammed Ali Alshara

“…The proposed methodology includes collecting cryptocurrency data and precious metal data from Coindesk and BullionVault, respectively, and then finding the optimal model input combination for each cryptocurrency by lag adjustment and correlating feature selection. Hyperparameter tuning was performed by trial-and-error technique, and an early stopping function was applied to minimize time and space complexity. …”
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