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2061
Genome-wide identification and expression analyses of CYP450 genes in Chrysanthemum indicum
Published 2025-05-01“…Conclusions The genome-wide analyses of cytochrome P450 superfamily offers essential genomic resources for functional studies of CiCYP450 genes, and is significant for the molecular breeding of Chrysanthemum.…”
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2062
A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro
Published 2024-12-01“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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2063
Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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2064
Photonics-Aided THz Integrated Sensing and Communication System Based on a Subcarrier-Chirp Inter-Embedded Waveform
Published 2025-01-01“…Simultaneously, multi-user detection with an 8-mm ranging resolution is also realized. …”
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2065
IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images
Published 2025-05-01“…These insights significantly bolster the arsenal of tools available for AD diagnostics and contribute to the broader narrative of deciphering brain functionality through state-of-the-art imaging modalities.…”
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2066
Validation of a 60K SNP chip for caribou (Rangifer tarandus) for use in wildlife forensics, conservation, and management
Published 2024-12-01“…The SNP chip was shown to be robust, highly sensitive, reliable, and accurate at more than 10-fold below the recommended DNA input. Biological source of DNA had minor impact, even with fecal pellets given sufficient amount of host DNA. …”
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2067
Rapid flips between warm and cold extremes in a warming world
Published 2025-04-01Get full text
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2068
Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage
Published 2025-02-01“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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2069
Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica
Published 2016-03-01“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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2070
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2071
BDNF Val66Met polymorphism moderates associations between physical activity and neurocognitive outcomes in older adults
Published 2025-04-01“…In moderated mediation analyses examining cognitive outcomes, plasma p‐tau181 selectively mediated the relationship between PA and executive function in Val/Val participants. …”
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2072
Spatial Pattern and Evolutionary Characteristics of Settlements in Dianchi River Basin from the Perspective of Toponymy
Published 2025-04-01“…By constructing a coupling analysis framework of toponym semantics and spatial attributes, this research confirms the “spatio-temporal code” function of toponym in the process reconstruction of human settlements, and the capability to analyze multi-source heterogeneous data based on the aforesaid function provides a new analytical methodology for the research on watershed human settlements. …”
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2073
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2074
Research on Pedestrians’ Visual Perception Characteristics Based on USGGS: A Case Study of the Six Inner-City Districts of Tianjin
Published 2025-05-01“…The core objective of the research is to propose strategies to optimize the greening structure of urban streets by analyzing the correlation between USGGS and visual perception of pedestrians, so as to enhance the quality of the visual environment of street pedestrians, improve the urban human settlement environment and promote the organic integration of the urban ecological and humanistic environments, thus providing a new way of thinking for urban planning and construction, and promoting the high-quality and sustainable development of urban street space.MethodsThe research selects the six inner-city districts of Tianjin City as the research area, utilizes Baidu street view image (SVI) as data source, and collect SVIs and their coordinates in the six districts in 2019 by calling Baidu API, with a total of 17,326 points selected and 13,281 valid samples obtained after screening. …”
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2075
WHSC1/NSD2 regulates immune infiltration in prostate cancer
Published 2021-02-01Get full text
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2076
Improving the understanding and interpretation of myeloma screening among resident doctors and physician associates: a quality improvement project
Published 2025-06-01“…Introduction: Myeloma is the second most common blood cancer in the UK, with a median age at diagnosis of 72.6 years.1 Patients with myeloma can initially present with vague and non-specific symptoms, making early diagnosis challenging. To improve early detection, a myeloma screen is commonly requested on medical wards. …”
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2077
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2078
HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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2079
Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging
Published 2025-03-01“…Following intravenous administration, MRI and MPI functionalities were analyzed through phantom studies and in vivo murine models.Results: Coated M55 NPs displayed high colloidal stability in water and effective functionalization. …”
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2080
Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes
Published 2024-12-01“…IC spans five function domains: Locomotor, psychological, cognitive, vitality, and sensory (including vision and hearing). …”
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