Morpho-Molecular and Genomic Characterization of <i>Penicillium mexicanum</i> Isolates Retrieved from a Forsaken Gold Mine by João Trovão, Fabiana Soares, Diana Sofia Paiva, António Portugal

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Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases by He Lu, Yaohui Jiang, Rui Luo, Dexing Zhou, Feihu Zheng, Liran Shi, He Zhang, Yong Wang, Xiaodong Xu, Renfang Zou, Yujing Zhou, Shuai Ren, Xiaocheng Wang, Haiqiang Sang

“…A significant benefit associated with this technology lies in its capacity to retain the functional and intrinsic properties of the source cells. …”
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Rossby Number Regime, Convection Suppression, and Dynamo-generated Magnetism in Inflated Hot Jupiters by Albert Elias-López, Matteo Cantiello, Daniele Viganò, Fabio Del Sordo, Simranpreet Kaur, Clàudia Soriano-Guerrero

“…We recover magnetic field strengths for inflated HJs by applying well-known scaling laws for fast rotators. When strong heat sources are applied mostly in the outer envelope and outside the dynamo region, as realistic ohmic models predict, convection in the dynamo region often breaks down. …”
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Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates by Pedro A. Reyes-Castillo, Ana Laura Esquivel-Campos, Edgar Torres-Maravilla, Eduardo Zúñiga-León, Felipe Mendoza-Pérez, Rosa González-Vázquez, María Guadalupe Córdova-Espinoza, María Angélica Gutiérrez-Nava, Raquel González-Vázquez, Lino Mayorga-Reyes

“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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Predictive model for coronavirus disease 2019 severity based on blood biomarkers: a retrospective study by Liu Xiaoyan, Bao Zhongying, Duan Shuhong, Sun Jing, Zhang Yijie, Zhang Jie, Liu Jingxin

“…Emergency department data functioned as an independent external validation set to test the model’s generalizability.ResultsThe study included 1,007 patients, with 778 in the training set and 229 in the validation set. …”
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Bayesian Denoising Algorithm for Low SNR Photon-Counting Lidar Data via Probabilistic Parameter Optimization Based on Signal and Noise Distribution by Qi Liu, Jian Yang, Yue Ma, Wenbo Yu, Qijin Han, Zhibiao Zhou, Song Li

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Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…This study provided a valuable resource for understanding the molecular basis of JD, potentially contributing to the genetic improvement of JD resistance in dairy cattle.…”
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CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…Methods Tumor Immune Estimation Resource (TIMER), The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases were utilized for bioinformatics analysis. …”
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Statistics on the Industry Structure of the Russian Economy and its Optimization Model by O. V. Morozov, M. A. Vasiliev

“…Optimization of the scale of industries is the formation of structural conditions for a more efficient functioning of the Russian economy; it can be recognized as a macroeconomic condition and a strategic reserve for the economic growth.…”
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Advances in Wearable Biosensors for Wound Healing and Infection Monitoring by Dang-Khoa Vo, Kieu The Loan Trinh

“…Wound healing is a complicated biological process that is important for restoring tissue integrity and function after injury. Infection, usually due to bacterial colonization, significantly complicates this process by hindering the course of healing and enhancing the chances of systemic complications. …”
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HIV-associated neurocognitive disorders in Africa: challenges, peculiarities, and future directions by Tobi Olajide, Evelyn Ogungbemi, Gideon Olajide, Deborah Ogundijo, Oluwanifemi Osakuade, Favour Moshood

“…Enhancing awareness, education, and capacity- building initiatives can improve early detection and management of neurocognitive disorders among individuals living with HIV. …”
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Epidemiology of amyotrophic lateral sclerosis in the Krasnoyarsk region by E. A. Ermilov, N. V. Isaeva

“…The increase in the incidence and detection of ALS emphasizes the need to develop new approaches to the treatment and rehabilitation of patients with ALS.…”
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Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS by Jessica O. Becker, Sara K. Shijo, Huu-Hien Huynh, Katrina L. Forrest, Michael J. MacCoss, Michelle A. Emrick, Elisha Goonatilleke, Andrew N. Hoofnagle

“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Post-treatment evaluation showed normalized complement C3 and C4 levels, stabilized platelet and hemoglobin levels, and gradual normalization of liver function. Renal function improved gradually, and a bone marrow biopsy revealed no fragmented red blood cells. …”
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Multimodal AI and Large Language Models for Orthopantomography Radiology Report Generation and Q&A by Chirath Dasanayaka, Kanishka Dandeniya, Maheshi B. Dissanayake, Chandira Gunasena, Ruwan Jayasinghe

“…In addition, the proposed solution includes a question-answering platform in the native Sinhala language, alongside the English language, designed to function as a chatbot for dental-related queries. We hope that this platform will eventually bridge the gap between dental services and patients, created due to a lack of human resources. …”
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Iodine deficiency as an environmental risk factor for thyroid gland diseases in animals by І. P. Ligomina, I. M. Sokulskyi, V. M. Sokolyuk, B. V. Gutyj, L. M. Soloviova

“…The situation is complicated in the biogeochemical zones of Ukraine, where insufficient or excessive content of mobile forms of microelements in soils and water sources determines the biological reaction of local flora and fauna. …”
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Genome-Wide Association Study of Immune Indices in Yaks by Daoning Yu, Xiaoming Ma, Chun Huang, Tong Wang, Mengfan Zhang, Fen Feng, Xiaoyun Wu, Yongfu La, Xian Guo, Ping Yan, Derong Zhang, Chunnian Liang

“…The yak is a vital livestock resource on the Qinghai–Tibet Plateau, renowned for its strong disease resistance and high-quality meat. …”
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Untargeted Metabolomics Reveals Distinct Anthocyanin Profiles in Napier Grass (<i>Pennisetum purpureum</i> Schumach.) Cultivars by Zhi-Yue Wang, Pei-Yin Lin, Chwan-Yang Hong, Kevin Chi-Chung Chou, Ting-Jang Lu

“…Plant secondary metabolites regulate plant growth and serve as valuable pharmaceutical resources. Napier grass (<i>Pennisetum purpureum</i> Schumach.), a Poaceae species, shows potential as a functional food. …”
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Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation by A. S. Frolova, A. G. Volkova, O. V. Paina, P. V. Kozhokar, K. A. Ekushov, Zh. Z. Rakhmanova, L. A. Cvetkova, E. D. Dobrovolskaya, B. I. Smirnov, E. A. Kulagin, T. A. Bykova, E. V. Semenova, L. S. Zubarovskaya

“…When comparing the intensity of conditioning regimens (MACvsRIC) in remission of the underlying disease, we did not get significant differences in the incidence of PC (p&gt;0.05). Graft source, donor type, HLA-compatibility, recipient gender did not affect the incidence of PC (p&gt;0.05). …”
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