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Trends and advances in Leptospira, a bibliometric analysis
Published 2025-01-01“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Epidemiology of Disability of Adult Population in the Russian Federation
Published 2019-11-01“…In one elderly patient older than 60 years, on average, four to five different chronic diseases are detected. The accumulation of impaired functions of organs and systems helps to reduce the adaptive capacity of the body and is associated with limited life, which entails an increase in the risks of disability in the elderly and the need for medical and social rehabilitation. …”
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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage
Published 2025-02-01“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica
Published 2016-03-01“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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WHSC1/NSD2 regulates immune infiltration in prostate cancer
Published 2021-02-01Get full text
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Improving the understanding and interpretation of myeloma screening among resident doctors and physician associates: a quality improvement project
Published 2025-06-01“…Introduction: Myeloma is the second most common blood cancer in the UK, with a median age at diagnosis of 72.6 years.1 Patients with myeloma can initially present with vague and non-specific symptoms, making early diagnosis challenging. To improve early detection, a myeloma screen is commonly requested on medical wards. …”
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Potential physiological mechanisms behind variation in rainbow trout (Oncorhynchus mykiss) to biosynthesize EPA and DHA when reared on plant oil replacement feeds
Published 2025-04-01“…The omega-3 fatty acids, docosahexaenoic acid (DHA; 22:6n-3) and eicosapentaenoic acid (EPA; 20:5n-3), are of primary concern as they provide significant health benefits such as reducing inflammation and improving heart and health function. However, the DHA; 22:6n-3 and EPA; 20:5n-3 available for aquaculture feeds is primarily provided by fish oil which is already limited in availability and expensive, and dietary lipids are consistently being replaced with oil sourced from plants. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging
Published 2025-03-01“…Following intravenous administration, MRI and MPI functionalities were analyzed through phantom studies and in vivo murine models.Results: Coated M55 NPs displayed high colloidal stability in water and effective functionalization. …”
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Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes
Published 2024-12-01“…IC spans five function domains: Locomotor, psychological, cognitive, vitality, and sensory (including vision and hearing). …”
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Landscape of extracellular small RNA and identification of biomarkers in multiple human cancers
Published 2025-08-01“…Summary: Extracellular RNAs (exRNAs) in biofluids, sourced from diverse tissues, exhibit various biological functions and diagnostic potential. …”
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Comparative nutrient and sensory analysis of eight different commercial Chlorella powders
Published 2025-06-01Get full text
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Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes
Published 2025-02-01“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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