Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. by Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
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A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…We also show that apicalized Punt does not produce an ectopic signal, indicating that the apical pool of Dpp is not a significant signaling source even when presented with Punt. Instead, we find that basolateral presentation of Punt is required for optimal signaling. …”
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Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
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Canada goose fecal microbiota correlate with geography more than host‐associated factors by Joshua C. Gil, Heather R. Skeen, Celeste Cuellar, Sarah M. Hird

“…This work also suggests that there is a minimum geographic distance, likely associated with sufficient variation in habitat, climate, and local food sources, that must be reached before significant differences in the microbiota between two populations can be detected.…”
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Synthesis of Molecularly Imprinted Polymers for Selective Extraction Followed by Solid Phase Determination of Metformin in Pharmaceutical Preparation and in Human Serum by Rana A. Kamal Aldeen, Yehya K. Al-Bayati

“…A solid-phase extraction (SPE) syringe packed with molecular imprinted polymers (MIPs) was employed to selectively separate and pre-concentrate the Metformin in multiple pharmaceutical drugs from several sources. The human serum was based on the use of deionized water to dilute the serum, followed by the heating of the serum with methanol. …”
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Strain Monitoring of Vertical Axis Wind Turbine Tower Using Fiber Bragg Gratings by Bastien Van Esbeen, Valentin Manto, Damien Kinet, Corentin Guyot, Christophe Caucheteur

“…Afterwards, by using power spectral density (PSD) on the strain signals, three sources of tower oscillations are discovered: wind force, structure unbalance, and 1st tower mode resonance, each with its intrinsic frequency. …”
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Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs by Kathryn L. Wofford, Kevin D. Browne, David J. Loane, David F. Meaney, D. Kacy Cullen

“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
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Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics by Salvatore Benfatto, Martin Sill, David T. W. Jones, Stefan M. Pfister, Felix Sahm, Andreas von Deimling, David Capper, Volker Hovestadt

“…Here, we describe an interpretable framework to explain the classifier’s decisions. We show that functional genomic regions of various sizes are predominantly employed to distinguish between different tumor classes, ranging from enhancers and CpG islands to large-scale heterochromatic domains. …”
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Nutritional Components and Strong Antioxidant Components of Finger Millet (Eleusine coracana (L.) Gaertn.) by LIU Jiamin, WANG Sainan, CHEN Danni, SONG Kerong, LI Kangyuan, CHEN Liping, WANG Jiawei, CAO Yong, XIAO Suyao

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Seasonal soil health dynamics in soy-wheat relay intercropping by Jennifer B. Thompson, Thomas F. Döring, Timothy M. Bowles, Steffen Kolb, Sonoko D. Bellingrath-Kimura, Moritz Reckling

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The barley genome sequence assembly reveals three additional members of the CslF (1,3;1,4)-β-glucan synthase gene family. by Miriam Schreiber, Frank Wright, Katrin MacKenzie, Pete E Hedley, Julian G Schwerdt, Alan Little, Rachel A Burton, Geoffrey B Fincher, David Marshall, Robbie Waugh, Claire Halpin

“…This significant divergence within the gene family might be related to multiple functions of (1,3;1,4)-β-glucans in the Poaceae. Emerging genomic and global expression data for barley and other cereals is a powerful resource for characterising the evolution and dynamics of complete gene families. …”
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Application and Suggestions of Morpholine Ring as a Lysosome Targeting Group by Xuelian Liu, Ximeng Zhang, Yinghong Han, Xingrui Li, Jinyao Li

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Programming‐Assisted Imaging of Cellular Nitric Oxide Efflux Gradients and Directionality via Carbon Nanotube Sensors by Ivon Acosta Ramirez, Sruti Das Choudhury, Carley Conover, Omer Sadak, Nicole M. Iverson

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Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria by Nirasha Atapattu, Nicolas Justus, Hariniha Selvarajan, Mitzchilouise Baylosis, Marc Schieven, Kalindi D. Morgan

“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
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The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters by Ambreesh Khurana, Sourav Chatterjee

“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
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Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability by Huangzhe Dai, Chengqian Zhang, Hao Hu, Zhezai Hu, Haonan Sun, Kan Liu, Tiefeng Li, Jianzhong Fu, Peng Zhao, Huayong Yang

“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer by Yixuan Wang, Nan Li, Shuanlong Che, Tiefeng Jin, Junjie Piao, Shuangping Liu, Zhenhua Lin

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Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Characterization of all life stages of Tenebrio molitor: Envisioning innovative applications for this edible insect by Nuno Muñoz-Seijas, Helena Fernandes, José Eugenio López-Periago, David Outeiriño, María Guadalupe Morán-Aguilar, José Manuel Domínguez, José Manuel Salgado

“…The human food security is unavoidably dependent on exploring novel nutritional sources, such as edible insects. However, insects farming needs to improve their rearing practices, such as extracting value from all growing stages, from larvae until adults. …”
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