Views, feelings, and thoughts of first-time mothers regarding breastfeeding in public: a qualitative study by Aslıhan Aksu, Ruveyda-Sultan Darğın, Gülnisa Küpelikılıç

“…The MAXQDA software was used for coding and identifying relationships between themes and sub-themes. …”
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Perceptions and acceptability of co-administered albendazole, ivermectin and azithromycin mass drug administration, among the health workforce and recipient communities in Ethiopia... by Scott McPherson, Dereje Geleta, Getinet Tafese, Temesgen Tafese, Sinkinesh Behaksira, Hiwot Solomon, Birhanu Oljira, Hirpa Miecha, Lalisa Gemechu, Kaleab Debebe, Biruck Kebede, Teshome Gebre, Fikreab Kebede, Fikre Seife, Fentahun Tadesse, Belete Mammo, Abraham Aseffa, Anthony W Solomon, David C W Mabey, Michael Marks, Endalamaw Gadisa

“…This has historically required multiple distinct campaigns, each targeting one or more NTDs, representing a strain on both the recipient communities and the local health workforce implementing the distribution. …”
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Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer. by Joanna Lopacinska-Jørgensen, Douglas V N P Oliveira, Guy Wayne Novotny, Claus K Høgdall, Estrid V Høgdall

“…MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression primarily by targeting messenger RNA (mRNA) transcripts. …”
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Overcoming temozolomide resistance in glioma: recent advances and mechanistic insights by Hengzeng Li, Yahui Wu, Yue Chen, Jinquan Lv, Chengkang Qu, Tingjie Mei, Yunfan Zheng, Cheng Ye, Feifei Li, Shuo Ge, Anhui Yao, Liyun Jia

“…Novel therapeutic approaches that target DNA repair pathways and manipulate autophagy are highlighted. …”
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Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene. by Lorenza Mittempergher, Anna M Piskorz, Astrid J Bosma, Magali Michaut, G Bea A Wisman, Roelof J C Kluin, Marja Nieuwland, Wim Brugman, Kevin J W van der Ven, Francesco Marass, James Morris, Nitzan Rosenfeld, Mercedes Jimenez-Linan, Steven de Jong, Ate G J van der Zee, James D Brenton, René Bernards

“…Here, we report on a study to find such new therapeutic targets for HGSOC using exome-capture sequencing approach targeting all kinase genes in 127 patient samples. …”
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Role of MicroRNAs in Chronic Myeloid Leukemia (CML) Treatment, Biomarkers, and Resistance to Tyrosine Kinase Inhibitor: A Bioinformatics-Based Analysis by Syarifah Faezah binti Syed Mohamad, Rabiatul Adawiyah Ramlee, Marjanu Hikmah Elias

“…Therefore, microRNAs (miRNAs) have emerged as potential alternative therapies. These short, non-coding RNAs (20-22 nucleotides) regulate gene expression by binding to the 3' untranslated region (3'UTR) of target genes. …”
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CRISPR/Cas13 sgRNA‐Mediated RNA–RNA Interaction Mapping in Live Cells with APOBEC RNA Editing by Li‐Ting Diao, Shu‐Juan Xie, Wan‐Yi Xu, Hai‐Hui Zhang, Ya‐Rui Hou, Yan‐Xia Hu, Xin‐Xiang Liang, Jun‐Bin Liang, Qi Zhang, Zhen‐Dong Xiao

“…Abstract Current research on long non‐coding RNA (lncRNA) has predominantly focused on identifying their protein partners and genomic binding sites, leaving their RNA partners largely unknown. …”
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Acceptability and implementation potential of a health literacy intervention to increase colorectal cancer screening in deprived areas: A qualitative study of patients and general... by Alix Boirot, Maria Claudia Addamiano, Clémence Casanova, Niamh M Redmond, Géraldine Cazorla, Michel Rotily, Anne-Marie Schott-Petelaz, Christian Balamou, Zineb Doukhi, Myriam Kaou, Françoise Couranjou, Julien Mancini, Cyrille Delpierre, Marie-Anne Durand, Aurore Lamouroux

“…The interviews were conducted by telephone or videoconference and analysed thematically using Nvivo software and dual independent coding.<h4>Results</h4>95% of GPs expressed a clear preference for the video over the brochure. …”
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PKM2-driven metabolic reprogramming in digestive system tumors: mechanisms, therapeutic advances, and clinical challenges by Xinyao Huang, Jianjun He, Haonan Sun, Yi Wu, Renjun Gu, Renjun Gu, Ziyun Li

“…Therapeutic strategies targeting PKM2 primarily aim to reverse the Warburg effect or inhibit compensatory metabolic pathways; however, their clinical translation remains challenging. …”
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Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing by Nami Motosugi, Keita Hasegawa, Natsumi Kurosaki, Erika Kawaguchi, Kenji Izumi, Yumi iida, Misaki Higashiseto, Keiko Yokoyama, Ayumi Sasaki, Kazuhiko Nakabayashi, Atsushi Fukuda

“…While Cas9-mediated non-homologous end joining (NHEJ) targeting the XIST promoter can induce DNA demethylation and restore XCI by reactivating XIST, its efficiency remains low. …”
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Identification of biomarkers related to propionate metabolism in schizophrenia by Weiqi Xie, Zhihong Luo, Jiang Xiao, Xuehua Zhang, Chanjuan Zhang, Ping Yang, Liang Li

“…Potential biomarker-targeted drugs were identified by exploring the DrugBank database; notably, LY96 exhibited higher binding affinities for four drugs, with docking scores consistently below-5 kcal/mol. …”
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LncRNA NEAT1 regulation of the miR-101-3p/RAC1 axis affects cervical cancer aerobic glycolysis and progression by Lingling Cao, Wumidan Abudureheman, Guqun Shen, Yunshan Ouyang, Wang Yang, Qian Zhao, Tianze Lu, Chen Lin

“…Abstract Cervical cancer is a prevalent malignancy among women worldwide. Long-chain non-coding rna (lncRNAs) play a key role in the development of several cancers. …”
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Inflammation-Induced Klotho Deficiency: A Possible Key Driver of Chronic Kidney Disease Progression by Liang Y, Zhang Q, Qian JR, Li SS, Liu QF

“…By focusing on the interplay between inflammation and Klotho, the present review provides novel potential therapeutic strategies such as correcting epigenetic and non-epigenetic abnormalities for treating CKD by targeting this specific axis.Keywords: inflammation, Klotho, chronic kidney disease, epigenetics, non-epigenetics, kidney fibrosis…”
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Miltefosine for the treatment of cutaneous leishmaniasis-A pilot study from Ethiopia. by Saskia van Henten, Annisa Befekadu Tesfaye, Seid Getahun Abdela, Feleke Tilahun, Helina Fikre, Jozefien Buyze, Mekibib Kassa, Lieselotte Cnops, Myrthe Pareyn, Rezika Mohammed, Florian Vogt, Ermias Diro, Johan van Griensven

“…Outcomes were documented for day 28, 90 and 180, both per site, and pooled, adjusting for site as a fixed effect with effect coding. Among 94 included patients (32 in Gondar, 62 in Boru Meda), median lesion duration was 12 months, median size six cm, and mucosal involvement (46.8%) and diffuse (30.9%) lesions were common. …”
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PiRNA hsa_pir_018849 promotes the proliferation and invasion of osteosarcoma cells by regulating the stability of CCN5 mRNA by Jiale Huang, Saishuai Yang, Peng Liu, He Jiang, Zhiming Cui, Jiajia Chen

“…Hsa_piR_018849 reduced the stability of CCN5 by binding to the coding sequence (CDS) region of CCN5 mRNA. Conclusion PiRNA hsa_piR_018849 regulates the function of osteosarcoma cells by targeting and inhibiting the expression of CCN5.…”
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Determinants of postnatal care service utilization among mothers of Mangochi district, Malawi: a community-based cross- sectional study by Jonas, Sagawa, Allen, Kabagenyi, Godwin, Turyasingura, Saul Eric, Mwale

“…A transcribed semi-structured questionnaire was pre- tested, modified and used to collect data on socio-demographic characteristics and maternal related factors. Data was coded in EpiData version 3.1 and analysed in Stata version 12. …”
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Identifying Factors Affecting Self-Development of Iranian TV School Teachers: Report of A Qualitative Study by abbas mohammadi, maede arshadrad

“…After reviewing and organizing the interview transcripts, initial concept codes were identified using an inductive approach, and similar codes were grouped into specific categories. …”
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Hsa_circ_0001756 drives gastric cancer glycolysis by increasing the expression and stability of PGK1 mRNA by Long Qian, Long Qian, Long Qian, Luman Wang, Hao Chen, Song Wang, Song Wang, Yinfen Hou, Li Xu, Li Xu, Yabin Xia, Yabin Xia, Maoqi Xu, Xiaoxu Huang, Xiaoxu Huang

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MiR-204/ZEB2 axis functions as key mediator for MALAT1-induced epithelial–mesenchymal transition in breast cancer by Yuzhou Wang, Yijin Zhou, Zhicheng Yang, Baoying Chen, Wennan Huang, Yongyuan Liu, Ying Zhang

“…Long non-coding RNAs recently were identified as key mediators of cancer metastasis. …”
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Comprehensive mitochondrial genomics of Fasciola gigantica from Sudan: insights into genetic diversity, evolutionary dynamics, and host adaptation by Bashir Salim, Nouh S. Mohamed, Kamal Ibrahim, Saeed Alasmari, Elisha Chatanga, Elisha Chatanga, Yuma Ohari, Nariaki Nonaka, Mohammad A. Alsaad, Faisal Almathen, Ryo Nakao, Ryo Nakao, Ryo Nakao

“…The observed diversity, particularly within non-coding and variable coding regions, underscores the influence of regional evolutionary pressures and host-associated adaptations. …”
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