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1781
MOLECULAR MARKERS OF SENSITIVITY AND RESISTANCE OF COLORECTAL CANCER TO ANTI-EGFR T
Published 2016-04-01“…Assessment of such markers is mandatory when EGFR targeting is considered. An analysis of tumor DNA for mutations in coding regions of KRAS and NRAS genes has become a standard procedure; the occurrence of these mutations is within 45-65%. …”
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1782
CRISPR/dCas12a-mediated activation of SlPAL2 enhances tomato resistance against bacterial canker disease.
Published 2025-01-01“…In this study, we engineered tomato plants by fusing the SET-domain of the SlATX1 coding gene, a histone H3 lysine 4 tri-methyltransferase, to dCas12a, targeting the SlPAL2 promoter with the aim to increase PAL2 gene expression. …”
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1783
Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data.
Published 2009-01-01“…<h4>Background</h4>MicroRNAs (miRNAs) are short, non-coding RNA regulators of protein coding genes. miRNAs play a very important role in diverse biological processes and various diseases. …”
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1784
The Constant Comparative Method of Qualitative Analysis
Published 2008-11-01“…If the analyst wishes to convert qualitative data into crudely quantifiable form so that he can provisionally test a hypothesis, he codes the data first and then analyzes it. He makes an effort to code “all relevant data [that] can be brought to bear on a point,” and then systematically assembles, assesses and analyzes these data in a fashion that will “constitute proof for a given proposition.” 2.) …”
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1785
Agile Digital Transformation in Local Government: An Extreme Programming Approach to Public Service Mall Applications
Published 2025-06-01“…Utilizing the Extreme Programming (XP) methodology, which focuses on iterative and collaborative software development, the application follows five main phases: planning, design, coding, testing, and release. Key features of the application include a service search function, a booking code-based queue system, service history tracking, and a user dashboard for seamless interaction. …”
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1786
Family Involvement in Early Childhood Education and Care: Insights from Portuguese and Norwegian Curriculum Frameworks
Published 2024-12-01“…Through content analysis of the curriculum frameworks from both nations, two primary themes emerge through coding: active involvement in the educational process and collaborative partnerships. …”
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1787
Designing a mobile health platform for effective medical records management in hospitals
Published 2025-04-01“…This application helps the healthcare employees for easy data retrieval and effective clinical decision making. Medical Records Management (MRM) for Android and iOS platforms, utilizing Low Code and No Code (LCNC) software development platforms was developed and implemented in hospital. …”
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1788
HOW TO ANALYZE BIG DATA: A STUDY ON UNDERSTANDING WHAT THE TURKISH THINK ABOUT SYRIAN REFUGEE CRISIS
Published 2019-07-01“…This model includes working with the comments through coding. All the comments are coded in three different categories.…”
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1789
Föreställningar om läsande och läsundervisning hos lärare i svenska som andraspråk
Published 2020-10-01“…The teachers’ narrow view of reading and reading education was revealed in the analysis, with emphasis on practices of coding and meaning making, and on discourses of skills and processes. …”
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1790
Information-extremе machine learning for object identification on the terrain
Published 2016-06-01“…Kulbak's information measure, which is a function of false omission rate and positive predictive value of decision-making and it also allows machine learning on imbalanced dataset.…”
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1791
COVID for One: Identifying Obstacles to Self-Management of COVID-19 for Single Adults
Published 2024-12-01“…Interviews were transcribed for coding and thematic analysis. Analysis of patient interview data identified 4 themes: Dealing with Isolation, Dying Alone, Managing Stigma, and Making a Support Plan. …”
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1792
The synergistic role of gut microbiota and RNA in metabolic diseases: mechanisms and therapeutic insights
Published 2025-01-01“…By exploring the molecular mechanisms, particularly how gut microbiota-derived signals modulate RNA pathways, the review underscores the potential of targeting this axis for therapeutic interventions. …”
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1793
Pro-Inflammatory Properties of Salivary Gland-Derived Fibroblasts—Implications in Sjögren’s Disease
Published 2025-04-01“…Treatment of SGF with the bromodomain inhibitor I-BET suppressed IL1- and LPS-induced expression of all eRNAs tested, as well as their associated pro-inflammatory coding transcripts. Transfection of SGF with antisense nucleotides targeting eCCL20 reduced the LPS-induced expression of this eRNA, as well as CCL20 expression and secretion. …”
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1794
Designing siRNAs against non-structural genes of all serotypes of Dengue virus using RNAi technology – A computational investigation
Published 2025-09-01“…These analyses anticipated three efficient siRNAs (S2, S3 and S11) that could have the capability to silence all the NS protein-coding genes employed by the DENV. Based on additional analysis including molecular dynamic (MD) simulation, principal component analysis (PCA) and free energy landscape (FEL), two siRNAs (S2 and S11) were recommended as potential therapeutics that could effectively degrade viral NS protein-coding genes through the RNAi pathway. …”
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1795
Unveiling host-genetic drivers of caecal microbial communities in chickens through genome-wide association studies
Published 2025-02-01“…Of note, we found markers nearby the genes coding for classical complement activation component C1q, ephrin receptors, and other immunity and inflammatory responses as well as genes coding for products associated with vitamin and co-factor metabolism. …”
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1796
Ethnographic investigation of patient–provider communication among African American men newly diagnosed with prostate cancer: a study protocol
Published 2020-09-01“…We will explore patients’ understanding of their diagnoses and treatment options, sources of support in decision-making, patient–provider communication and treatment decision-making processes. …”
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1797
Presentation the Model of Empowerment in Physical Education Teachers
Published 2023-07-01“…Based on this, a systematic approach including three main steps of open coding, axial coding and selective coding was used. …”
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1798
Curcumin as a promising therapeutic agent for diabetic neuropathy: from molecular mechanisms to functional recovery
Published 2025-08-01“…MicroRNAs (miRNAs or miR), which are small non-coding RNAs consisting of 19–25 nucleotides, are stable in circulation and can regulate multiple target genes. …”
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1799
Notched noise reveals differential improvement in the neural representation of the sound envelope
Published 2025-08-01“…Both auditory nerve fiber recordings (in Mongolian gerbils of either sex) and human psychophysics confirm that weak temporal coding at higher levels is improved when the target stimulus is presented in a spectrally flanking notched noise designed to reduce the cochlear gain. …”
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1800
Intratumoral microbiota: implications for cancer progression and treatment
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