An Autocatalytic Platform Combining a Nonlinear Hybridization Chain Reaction and DNAzyme to Detect microRNA by Hongbo Zhang, Xiuen Cao, Qubo Zhu

“…MicroRNAs (miRNAs) are small, non-coding RNAs that play pivotal roles in gene regulation; they are increasingly recognized as vital biomarkers for various diseases, notably cancer. …”
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“Conversing” With Qualitative Data: Enhancing Qualitative Research Through Large Language Models (LLMs) by Adam S. Hayes

“…This dialogue-like process speeds up traditional tasks—transcription, coding, theme identification—while sparking broader possibilities for exploration. …”
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Efficient in vivo labeling of endogenous proteins with SMART delineates retina cellular and synaptic organization by Chuanping Zhao, Yan Cao, Noor Ibrahim, Yuchen Wang, Kirill A. Martemyanov

“…It relies on reconstructing the targeted gene using Silently Mutate And Repair Template (SMART) where we mutate the gap sequence in the repair template to prevent its base pairing with the target DNA while maintaining the same amino acid coding. …”
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Emerging biomarkers for cancer diagnosis: Paving the way for precision oncology by Muhammad Zaid Salar, Ghulam Mustafa, Tanzeela Hassan, Iqra Rafiq, Muhammad Noman Tariq

“…In order to meet this issue, the combination of these biomarkers is recommended and found to be efficacious, such as, the integration of metabolomics and imaging techniques is found to be promising technique for precision oncology and targeted therapies against cancer. In this article, we will discuss the emerging biomarkers of cancer and how these bioassays are making the way for personalized medicine, precision oncology and targeted therapies. …”
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Functional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances. by Jaebum Kim, Ryan Cunningham, Brian James, Stefan Wyder, Joshua D Gibson, Oliver Niehuis, Evgeny M Zdobnov, Hugh M Robertson, Gene E Robinson, John H Werren, Saurabh Sinha

“…The framework uses cross-species comparison to improve the specificity of its predictions, and does so without relying upon non-coding sequence alignment. It is therefore well suited for comparative genomics across large evolutionary divergences, where existing alignment-based methods are not applicable. …”
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RETRACTED: Geometric Construction of Video Stereo Grid Space by Huangchuang Zhang, Ruoping Shi, Ge Li

“…In view of the above problems, this paper proposes a video stereo grid geometric space construction method based on GeoSOT-3D stereo grid coding and a camera imaging model to form a video stereo grid space model. …”
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Machine Learning Approach to Identifying Wrong-Site Surgeries Using Centers for Medicare and Medicaid Services Dataset: Development and Validation Study by Yuan-Hsin Chen, Ching-Hsuan Lin, Chiao-Hsin Fan, An Jim Long, Jeremiah Scholl, Yen-Pin Kao, Usman Iqbal, Yu-Chuan Jack Li

“…We developed an adapted Association Outlier Pattern (AOP) ML model to identify uncommon procedure-diagnosis combinations, specifically targeting discrepancies in laterality. The model was trained on data from 2017 to 2019 and tested on 2020 orthopedic procedures, using ICD-10-PCS (International Classification of Diseases, Tenth Revision, Procedure Coding System) codes to distinguish body part and laterality. …”
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Antisense oligonucleotide-mediated TRA2β poison exon inclusion induces the expression of a lncRNA with anti-tumor effects by Nathan K. Leclair, Mattia Brugiolo, SungHee Park, Maeva Devoucoux, Laura Urbanski, Brittany L. Angarola, Marina Yurieva, Olga Anczuków

“…Mechanistically, we find that the ASO functions by both decreasing TRA2β protein and inducing the expression of TRA2β-PE-containing transcripts that act as long non-coding RNAs to sequester nuclear proteins. Finally, TRA2β-PE-targeting ASOs are toxic to preclinical 3D organoid and in vivo patient-derived xenograft models. …”
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High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states. by Kevin A Wilkinson, Robert J Gorelick, Suzy M Vasa, Nicolas Guex, Alan Rein, David H Mathews, Morgan C Giddings, Kevin M Weeks

“…We also discover that noncoding regions functioning in a regulatory role have significantly lower (p-value < 0.0001) SHAPE reactivities, and hence more structure, than do viral coding regions that function as the template for protein synthesis. …”
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The Commercialization Model of Professional Sport Clubs by Zahra Sohrabi, Mehrdad Moharramzadeh, Rasool Nazari

“…In order to analyze the qualitative data, the two-stage open, theoretical coding method was used. Reliability and validity were confirmed through the percentage of intro-subject agreement and the approval of the statistical group and the interviewees. …”
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Exploring barriers and enabling factors for surgical task sharing with physician assistants in Liberia: a qualitative pre-implementation study by Håkon A Bolkan, Alex J van Duinen, Ankie van den Broek, Theophilus C Hampaye, Markus Jan Werz

“…Data was analysed in NVivo V.12 using deductive coding and the consolidated framework for implementation research as a guide.Setting Liberia has few surgical providers and a poor surgical infrastructure resulting in a very low surgical volume. …”
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PLGA-microspheres carried circ_0003251 alleviate intervertebral disc degeneration via the miR-637/AKT1 axis by Shouliang Xiong, Quanlai Zhao, Yu Zhang, Yifeng Li, Xiaoming Yang, Liang Xiao

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piRNAs as Potential Regulators of Mammary Gland Development and Pathology in Livestock by Wenjing Yu, Zixuan Zhang, Zhonghua Wang, Xusheng Dong, Qiuling Hou

“…We hypothesize that piRNAs may play a potential role in regulating both mammary gland development and mastitis, making them promising targets for enhancing mammary development and overall health in dairy cattle and providing a theoretical foundation for further piRNA applications in animal husbandry.…”
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Designing a Digital Branding Pattern in Healthy Agricultural Products by Abolghasem Mohammadnezhad Ali Zamini, Arezo Ahmadi danyali, Mahmoud Ahmadi Sharif

“…According to the indicators obtained in the research process and the analyzes performed on them, the final model was obtained using the coding method. Conclusion Digital branding of healthy agricultural products is centered around the creation of brand meaning and brand power, which initiates under influence of casual conditions, and makes sense with different strategy of digital brand creation and brand power, and strengthens the brand culture in the target community and visualizes the identity and personality of the digital brand of healthy agricultural products in the mind of the customer. …”
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Machine learning using genotype and gene-expression data identifies alterations of genes involved in infection susceptibility, antigen presentation and cytokine signalling as key c... by Nicholas Pudjihartono, Daniel Ho, Justin Martin O’Sullivan

“…We evaluated the robustness of our model’s feature ranking across 50 cross-validation runs.Results The top-ranked SNPs included rs7775055, which tags the human leukocyte antigen (HLA) class II haplotype DRB1*0801-DQA1*0401-DQB1*0402, and rs6679677, a non-coding variant that is in 100% linkage with with a coding variant in PTPN22. …”
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Biogenesis and function of extracellular miRNAs by Chihao Zhao, Xinlei Sun, Limin Li

“…Abstract Mature microRNAs (miRNAs) are 18–24-nucleotide non-coding RNAs with post-transcriptional regulatory functions and have been documented as an essential cornerstone of the genetic system. …”
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Diagnostic value of hsa_circ_0012138 in the chronic progression of obstructive nephropathy by Zhichao Huang, Fei Deng, Zebin Deng, Yinhuai Wang, Xu Cheng

“…As the frontier in non-coding RNA research, circRNA is involved in the pathological progress of ON, however, the correlation between hsa_circ_0012138 expression and renal function reversibility remains unknown. …”
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"Because at school, you can become somebody" - The perceived health and economic returns on secondary schooling in rural Burkina Faso. by Luisa K Werner, Jan Jabbarian, Moubassira Kagoné, Shannon McMahon, Julia Lemp, Aurélia Souares, Günther Fink, Jan-Walter De Neve

“…Systematic analysis was based on a grounded theory approach with a reading of transcripts, followed by coding of the narratives in NVivo 12.<h4>Results</h4>Respondents nearly universally perceived health benefits to schooling. …”
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Ovarian cancer and the heart: pathophysiology, chemotherapy-induced cardiotoxicity, and new therapeutic strategies by Megha Nair, Arun Samidurai, Anindita Das, Sham S. Kakar, Rakesh C. Kukreja

“…Emerging evidence suggests that non-coding RNAs including miRNAs and lncRNAs significantly influence OC through their multiple roles including tumor initiation, progression, metastasis, immune evasion, and chemoresistance, making them promising diagnostic markers and therapeutic targets. …”
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Training well-rounded healthcare professionals through developing religious/spiritual competencies: a grounded theory study in Iran by Akram Heidari, Abbas Abbaspour, Morteza Heidari

“…Data analysis included open, axial, and selective coding that were performed through constant comparisons to identify main themes and represent their interrelationships as a model. …”
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