MiR-192–5p targets cell cycle regulation in diabetic kidney disease via cyclin-dependent kinase inhibitor 3 by Biswajit Sahoo, Deendayal Das Mishra, Swasti Tiwari

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The ncRNA-AURKA Interaction in Hepatocellular Carcinoma: Insights into Oncogenic Pathways, Therapeutic Opportunities, and Future Challenges by Clarissa Joy C. Garcia, Luca Grisetti, Claudio Tiribelli, Devis Pascut

“…Emerging evidence highlights the critical role of non-coding RNAs (ncRNAs) in the regulation of Aurora kinase A (AURKA), one of the key hub genes involved in several key cancer pathways. …”
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LncRNA FAISL Inhibits Calpain 2‐Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer by Yunmei Zhang, Shiyu Wei, Zhengjie Chen, Rui Xu, Shu‐Rong Li, Lili You, Ruiyue Wu, Yin Zhang, Jian‐You Liao, Xiaoding Xu, Erwei Song, Man‐Li Luo

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Novel spirooxindole compounds as anticancer agents: targeting Plk4 kinase through design, synthesis, and molecular docking by Mervat S. Sammor, Almeqdad Y. Habashneh, Mahmoud A. Al-Sha'er, Sanaa K. Bardaweel, Mustafa M. El‐Abadelah

“…In conclusion, these findings support the potential of spirooxindole derivatives as selective and safe Plk4 inhibitors, offering a promising avenue for targeted cancer therapy with minimal toxicity to normal cells. …”
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Radar Scattering Analysis of Multi-Scale Complex Targets by Fast VSBR-MoM Method in Urban Scenes by Zhou Cong, Jihong Gu, Ying Zhang, Jie Yang, Dazhi Ding

“…By dividing the mixed multi-scale targets into sub-regions, different solvers are employed to compute the scattering contributions based on their varying electrical sizes. …”
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Implementing and Evaluating an Heterogeneous, Scalable, Tridiagonal Linear System Solver with OpenCL to Target FPGAs, GPUs, and CPUs by Hamish J. Macintosh, Jasmine E. Banks, Neil A. Kelson

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Precision and Characteristics of Satellite Spatial Quality Estimators’ Measurement Using an Edge Target Imaged with KOMPSAT-3A by Donghan Lee, Daesoon Park, Daehoon Yoo

“…The contents and results of this work were discussed by various satellite development organizations in the Geo-Spatial Working Group within CEOS WGCV IVOS from 2012 to 2019, and the Edge target Spatial quality Measurement Python code (ESMP) was developed in 2019 to reflect the findings of this workshop. …”
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A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…Rescue of punt mutants with transgenes altered in the targeting motif showed that flies expressing apicalized Punt due to the lack of a functional BLT displayed developmental defects, female sterility, and significant lethality. …”
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Magnetic Activity Evolution of Solar-like Stars. II. Sph–Ro Evolution of Kepler Main-sequence Targets by Savita Mathur, Ângela R. G. Santos, Zachary R. Claytor, Rafael A. García, Antoine Strugarek, Adam J. Finley, Quentin Noraz, Louis Amard, Paul G. Beck, Alfio Bonanno, Sylvain N. Breton, Allan S. Brun, Lyra Cao, Enrico Corsaro, Diego Godoy-Rivera, Stéphane Mathis, Dinil B. Palakkatharappil, Marc H. Pinsonneault, Jennifer van Saders

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Appraisal and simulation of 125I production yield with Low/Medium energy proton and deuteron particles on tellurium targets by Abdollah Khorshidi

“…Methods: In this research, the cyclotron in Karaj with deuteron energy of 20 MeV and proton energy of 30 MeV was considered to simulate the production of 125I using 124/125Te targets. Here, the 125Te(p,n)125I and 124Te(d,n)125I reactions cross sections were analyzed via TALYS code in optical potential model by changing diffusivity and radius, level density model, density of exciton model constituents, pre-equilibrium and equilibrium model by Hauser-Feshbach formalism, branching rates, and possibility of derived particle generation. …”
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DART-scale Impacts into a Complex Low-strength Target: Insights into Asteroid Dimorphos’s Interior from Simulations by Cem Berk Senel, Robert Luther, Özgür Karatekin, Gareth S. Collins, Steven Goderis, Philippe Claeys

“…Impacts were simulated using the iSALE-2D shock physics code over extended time frames of up to 60 s, with half-spheroidal targets resolving surface curvature effects. …”
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Role of MicroRNAs and Retroelements in the Pathogenesis of Atherosclerosis by R. N. Mustafin, E. A. Galieva

“…Therefore, it is important to search for new molecular targets in this direction, which can serve as transposons, which are sources of non-coding RNAs. …”
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Mechanism of crosstalk between DNA methylation and histone acetylation and related advances in diagnosis and treatment of premature ovarian failure by Jing Li, Qianhui Liao, Yurou Guo, Jiaheng Zhang, Ruyi Zhang, Qiyu Liu, Huiping Liu

“…These mechanisms provide new insights into the pathological basis of POF, identify potential biomarkers, and offer a theoretical framework for deciphering targeted intervention strategies and developing precision epigenetic therapies to delay POF progression.…”
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Osthole mitigates the myofibroblast properties in oral submucous fibrosis by suppressing the TGF-β/smad2 signaling pathway and NCK-AS1 expression by Po-Yu Yang, Pei-Ling Hsieh, Jung-Chun Yeh, Chun-Te Ho, Yi-Wen Liao, Yu-Lei Wei, Shih-Min Wang, Cheng-Chia Yu, Pei-Ming Chu

“…Background/purpose: Natural products are gaining increasing recognition as an alternative source for alleviating fibrosis as they can regulate various mediators or pathways against fibrosis by targeting non-coding RNAs. In the current study, we aimed to investigate the therapeutic effects of osthole in oral submucous fibrosis (OSF), a precancerous condition of the oral cavity. …”
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Establishment of a m6 A-associated lncRNAs-derived risk model for enhanced patient prognosis stratification and personalized therapy approaches in bladder cancer by Renhu Chen, Yuqing Ye, Yuxuan Zheng

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The Dialect of Hasawis and Bedouins in Al-Ahsa (Saudi Arabia): A Comparative Study by Махмуд Ель Салман, Абдулла Аль Фрідан

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High energy gain of ion-driven flux compression in cylindrical target with initial power-law radial density profile by Soheil Khoshbinfar

“…Here, we have proposed a new DT fuel initial density profile that improves final fusion yield in cylindrical targets in MTF. We have employed the Deira-4 MHD code to investigate the performance of these configurations. …”
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Drivers of Food Decision Making and Aspirations for the Future of the School Food Environment among Junior High School Students in Cape Coast, Ghana: a Photovoice Study by Elise C Reynolds, Christiana Nsiah-Asamoah, Harriet Okronipa, Nicholas F Russell, Madina Habib, Christine P Stewart

“…Background: Food decision making is a complex and dynamic process that influences diet and ultimately health. …”
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microRNA-497-5p-based screening identifies a novel synthetic lethal-type interaction via PKMYT1 and WEE1 in pleural mesothelioma by Nathanael Pruett, Sierra Wilferd, Anand Singh, Agnes Y. Choi, Shivani Dixit, Vivek Singh, Charlize Nguyen, Olivia Lin, David S. Schrump, Christopher L. Plaisier, Chuong D. Hoang

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miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells by Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven

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