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101
The impact of the nucleosome code on protein-coding sequence evolution in yeast.
Published 2008-11-01“…We identify nucleosome positioning as a likely candidate to set up such a DNA-level selective regime and use high-resolution microarray data in yeast to compare the evolution of coding sequence bound to or free from nucleosomes. …”
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102
A RNA-Seq Analysis of the Rat Supraoptic Nucleus Transcriptome: Effects of Salt Loading on Gene Expression.
Published 2015-01-01“…In addition, we compare the SON transcriptomes resolved by RNA-Seq methods with the SON transcriptomes determined by Affymetrix microarray methods in rats under the same osmotic conditions, and find that there are 6,466 genes present in the SON that are represented in both data sets, although 1,040 of the expressed genes were found only in the microarray data, and 2,762 of the expressed genes are selectively found in the RNA-Seq data and not the microarray data. …”
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103
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.
Published 2011-01-01“…In order to obtain a global view of the impact of Snail and Slug expression, we performed a microarray experiment using the MCF-7 breast cancer cell line, which does not express detectable levels of Snail or Slug. …”
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104
Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.
Published 2008-02-01“…Pre-treatment of rats with a selective inhibitor of Stat3, T40214, reduced the IL-6-mediated increase in cardiac Stat3 activity, blocked successful resuscitation by IL-6 and reversed IL-6-mediated protection from cardiac apoptosis. …”
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105
Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.
Published 2011-01-01“…High throughput techniques such as inference of gene regulatory networks from microarray experiments can objectively define signaling machinery in this disease. …”
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106
Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature
Published 2025-01-01“…Here, we use liquid chromatography–mass spectrometry and gene expression microarray to profile integrated intratumour metabolic heterogeneity, as a direct functional readout of adaptive responses of subclones to the tumour microenvironment. …”
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107
Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell...
Published 2016-01-01“…Here, we report on studies designed to uncover how tumour cells respond to sub-lethal doses of cisplatin. A microarray study revealed changes in gene expressions that occurred when A549 cells were exposed to a no-observed-effect level (NOEL) of cisplatin (e.g. the IC10). …”
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108
A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes.
Published 2011-01-01“…Selected candidate genes Npr3 and Thbs1, as well as Gys2, a non-QTL gene that otherwise passed our enrichment criteria were characterised, revealing novel functional effects consistent with a contribution to obesity.…”
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109
Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea
Published 2025-04-01“…Methods Firstly, the expression profiles of m6A-modified circRNA in left ventricular tissue of the CIH mouse model were examined using circRNA microarray analysis. Then, the expression level of selected circrRNA was compared by folding change filtration, and the consistency between them and microarray results was verified by MeRIP-qPCR. …”
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110
On-Chip DNA Assembly via Dielectrophoresis
Published 2025-01-01“…This work introduces a novel on-chip DNA assembly method via dielectrophoresis (DEP) that can potentially be integrated with microarray-based oligo synthesis on the same chip. Our DEP chip can selectively manipulate oligos and guide their movement without perturbing the surrounding fluid medium, thus aiding in DNA assembly. …”
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111
SLEPR: a sample-level enrichment-based pathway ranking method -- seeking biological themes through pathway-level consistency.
Published 2008-09-01“…Analysis of microarray and other high throughput data often involves identification of genes consistently up or down-regulated across samples as the first step in extraction of biological meaning. …”
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112
Translational profiling reveals novel gene expression changes in the direct and indirect pathways in a mouse model of levodopa induced dyskinesia
Published 2025-03-01“…Extracted ribosomal RNA was amplified, purified, and gene expression was quantified using microarray.ResultsOne hundred ninety-five significantly varying transcripts were identified among the four treatment groups. …”
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113
Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells.
Published 2021-01-01“…The results validated the microarray analysis, which showed a significant decrease in the mRNA as well as protein expression of the selected genes as the concentration of glucose increased. …”
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114
Prediction of gene expression in embryonic structures of Drosophila melanogaster.
Published 2007-07-01“…The use of high-throughput approaches, such as large-scale in situ hybridisation and genome-wide expression profiling via DNA microarrays, is beginning to provide insights into the complexities of development. …”
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115
MicroRNA profiling in human colon cancer cells during 5-fluorouracil-induced autophagy.
Published 2014-01-01“…The physiological importance of the miRNA-autophagy interconnection is only beginning to be elucidated. MiRNA microarray technology facilitates analysis of global miRNA expression in certain situations. …”
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116
Analysis of gene expression difference and biological process in chorionic villi of unexplained recurrent spontaneous abortion
Published 2024-12-01“…Abstract Objective To explore the biological relationship between the regulatory signal pathways involved in differentially expressed genes and recurrent spontaneous abortion (RSA) by analyzing the gene expression microarray data of unexplained RSA. Methods The gene expression profile data of chorionic villi from unexplained recurrent abortion with normal karyotype and selective induced abortion were compared. …”
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117
Regulation of neutrophil senescence by microRNAs.
Published 2011-01-01“…Total RNA from highly purified neutrophils was prepared and subjected to microarray analysis using the Agilent human miRNA microarray V3. …”
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118
Aberrant expression of shared master-key genes contributes to the immunopathogenesis in patients with juvenile spondyloarthritis.
Published 2014-01-01“…Microarray results and bioinformatical analysis revealed 745 differentially expressed genes involved in various inflammatory processes, while qRT-PCR analysis of selected genes confirmed data universality and specificity of expression profiles in jSpA patients. …”
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119
Differentially expressed circular RNAs and their diagnostic value in children with allergic rhinitis
Published 2025-08-01“…Methods Blood samples were collected from allergic rhinitis patients and healthy controls, and circular RNA microarray was performed. The expression of differentially expressed circular RNAs was verified via real-time quantitative reverse transcription polymerase chain reaction, and these RNAs were selected for Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses. …”
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120
Identification of G1-regulated genes in normally cycling human cells.
Published 2008-01-01“…<h4>Methodology and findings</h4>We used a robotic mitotic shake-off apparatus to select cells in late mitosis for genome-wide gene expression studies. …”
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