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281
Spatially resolved analysis of the T cell immune contexture in lung cancer-associated brain metastases
Published 2021-10-01“…The signal for each marker was measured in marker-selected tissue compartments, and associations between marker levels, tumor location, and major clinicopathological variables were studied. …”
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282
Tumor immune microenvironment permissive to metastatic progression of ING4-deficient breast cancer.
Published 2024-01-01“…To characterize the tumor immune microenvironment associated with ING4-deficient tumors, three approaches were employed in this study: First, tissue microarrays composed of 246 primary breast tumors including 97 ING4-deficient tumors were evaluated for the presence of selective immune markers, CD68, CD4, CD8, and PD-1, using immunohistochemical staining. …”
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283
Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review.
Published 2018-01-01“…Original English-language publications of microarray studies assessing radiation-induced changes in gene expression levels in human blood after external IR were included. …”
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284
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285
Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms
Published 2025-06-01“…Additionally, we processed the GSE53873 microarray dataset, which includes 19 pemphigus samples and 5 controls. …”
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286
Inhibitory Effect of PRMT5/MTA Inhibitor on MTAP‐Deficient Glioma May Be Influenced by Surrounding Normal Cells
Published 2024-12-01“…In vitro and in vivo experiments have demonstrated that MRTX1719, a small molecule that selectively binds PRMT5/MTA complex, significantly inhibits the proliferation of MTAP‐deficient tumors and has a weak toxic effect on normal cells. …”
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287
Etiology and outcomes of fetal renal abnormalities in Southern China: a single-tertiary-center study
Published 2025-08-01“…We retrospectively analyzed data from 1,019 cases for which chromosomal microarray analysis (CMA) was performed; 58 CMA-negative fetuses were selected for whole-exome sequencing (WES). …”
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288
A retrospective analysis of 6942 amniocentesis cases
Published 2025-08-01“…Among the single-method cases, Chromosomal Microarray Analysis (CMA) was the most frequently selected technique (14.18%). …”
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289
Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects
Published 2025-01-01“…However, further data are required to clarify ADORA3 expression patterns in liver cancer, mechanisms of action, and the potential for combination therapies to inform patient selection for future clinical trials. Methods: Patient-derived tissue microarrays and RNA-sequencing were employed to investigate ADORA3 expression. …”
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290
Identification and Cross-Platform Validation of Sparse Molecular Classifiers for Antibody-Mediated and T-Cell–Mediated Rejection After Kidney Transplantation
Published 2025-06-01“…Methods: In a discovery cohort of 224 kidney transplant biopsies, lasso regression was applied on microarray gene expression data to derive a molecular classifier for ABMR and TCMR, respectively. …”
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291
Decoding the prognostic landscape of LUAD: the interplay between N6-methyladenosine modification and immune microenvironment
Published 2024-12-01“…A risk score model was constructed using least absolute shrinkage and selection operator regression and validated in two independent cohorts and LUAD tissue microarrays. …”
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292
Effects of tumour-associated macrophages on cardia carcinoma progression
Published 2025-07-01“…Methods Cancer tissue and pericancer tissue samples from 80 patients with cardia carcinoma who underwent D2 radical surgery between January 2014 and January 2015 at Putian First Hospital were selected. Tissue microarrays were fabricated, and immunohistochemistry technology was used to detect the infiltration of TAMs (CD163 as a marker) and to analyse their relationship with the clinicopathological characteristics of the patients. …”
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293
MaGIC: a program to generate targeted marker sets for genome-wide association studies
Published 2004-12-01“…High-throughput genotyping technologies such as DNA pooling and DNA microarrays mean that whole-genome screens are now practical for complex disease gene discovery using association studies. …”
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294
Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.
Published 2012-01-01“…Expression studies of 50 selected candidate genes from this dataset resulted in the identification of 39 new genes that are expressed in vascular cells. …”
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295
The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells.
Published 2012-01-01“…<h4>Methodology/principal findings</h4>SOX18 was expressed in HUVEC using a recombinant adenoviral vector and the altered gene expression profile was analyzed using microarrays. Expression of several regulated candidate SOX18 target genes was verified by real-time PCR. …”
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296
Comprehensive analysis of microRNA expression profile in malignant glioma tissues
Published 2015-08-01“…We investigated the global miRNA profile of malignant glioma tissues with miRNA microarrays, deep sequencing and meta‐analysis. We selected miRNAs that were most frequently deregulated in glioblastoma tissues, as well as in peritumoral areas, in comparison with normal human brain. …”
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297
Revealing new mouse epicardial cell markers through transcriptomics.
Published 2010-06-01“…<h4>Methodology</h4>Using laser capture microscopy, we isolated the epicardial layer from the adult murine heart before or after cardiac infarction in wildtype mice and mice expressing a transgenic IGF-1 propeptide (mIGF-1) that enhances cardiac repair, and analyzed the transcription profile using DNA microarrays.<h4>Principal findings</h4>Expression of epithelial genes such as basonuclin, dermokine, and glycoprotein M6A are highly enriched in the epicardial layer, which maintains expression of selected embryonic genes involved in epicardial development in mIGF-1 transgenic hearts. …”
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298
Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Published 2015-01-01“…Selecting colorectal cancer (CRC) patients likely to respond to therapy remains a clinical challenge. …”
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299
Nonlinear Quantitative Radiation Sensitivity Prediction Model Based on NCI-60 Cancer Cell Lines
Published 2014-01-01“…Important radiation therapy (RT) related genes were selected by significance analysis of microarrays (SAM). …”
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300
Distribution of Recessive Genetic Defect Carriers in Holstein Friesian Cattle: A Polish Perspective
Published 2024-11-01“…The studies were performed using Illumina Infinium microarrays. Among both bulls and cows, the highest numbers of carriers were detected for HH5 (appropriately 6.7% and 5.4%). …”
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