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elective » effective (Expand Search), executive (Expand Search)
selective » seffective (Expand Search), sexecutive (Expand Search)
selection » detection (Expand Search)
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High reproducibility using sodium hydroxide-stripped long oligonucleotide DNA microarrays
Published 2005-01-01“…In addition, when there is limited availability of mRNA from tissue sources, RNA amplification can and is being used to produce sufficient quantities of cRNA for microarray hybridization. Taking advantage of the selective degradation of RNA under alkaline conditions, we have developed a method to “strip” glass-based oligonucleotide microarrays that use fluorescent RNA in the hybridization, while leaving the DNA oligonucleotide probes intact and usable for a second experiment. …”
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Microarray Data Analysis: From Hypotheses to Conclusions Using Gene Expression Data
Published 2004-01-01“…We review several commonly used methods for the design and analysis of microarray data. To begin with, some experimental design issues are addressed. …”
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A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
Published 2024-12-01“…These lectins have been specifically tailored to selectively bind to common N-glycan epitopes found in therapeutic IgG antibodies. …”
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CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Published 2024-11-01“…We used CRISPR screens to uncover the expanded network of genes controlling high mannose levels, followed by lectin microarrays to fully measure the complex effect of select regulators on glycosylation globally. …”
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Improving machine learning detection of Alzheimer disease using enhanced manta ray gene selection of Alzheimer gene expression datasets
Published 2025-08-01“…To alleviate such an effect, this study proposes a gene selection approach based on the parameter-free and large-scale manta ray foraging optimization algorithm. …”
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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
Published 2012-01-01“…Our work therefore identifies CCT020312 as a novel small molecule chemical tool for the selective activation of EIF2A-mediated translation control with utility for proof-of-concept applications in EIF2A-centered therapeutic approaches, and as a chemical starting point for pathway selective agent development. …”
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Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.
Published 2010-07-01“…<h4>Background</h4>Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. …”
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THE VALIDATION OF THE RESULTS OF MICROARRAY STUDIES OF ASSOCIATION BETWEEN GENE POLYMORPHISMS AND THE FREQUENCY OF RADIATION EXPOSURE MARKERS
Published 2014-06-01“…The results from the selective validation research into the association between genetic polymorphisms and the frequency of cytogenetic abnormalities on a large independent sample are analyzed. …”
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50
Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment
Published 2010-09-01“…Methodology: The spotted array consisted of 69 selected Salmonella-specific virulence gene probes (65bp each). …”
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51
Machine learning identification of molecular targets for medulloblastoma subgroups using microarray gene fingerprint analysis
Published 2025-01-01“…An artificial neural network (ANN) model trained on microarray gene expression data determined minimal gene combinations for each subgroup. …”
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52
Discovery of possible gene relationships through the application of self-organizing maps to DNA microarray databases.
Published 2014-01-01“…DNA microarrays and cell cycle synchronization experiments have made possible the study of the mechanisms of cell cycle regulation of Saccharomyces cerevisiae by simultaneously monitoring the expression levels of thousands of genes at specific time points. …”
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Molecular sub-classification of renal epithelial tumors using meta-analysis of gene expression microarrays.
Published 2011-01-01“…This algorithm may aid in selecting molecular therapies and may improve the accuracy of subtyping of renal cortical tumors.…”
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High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform
Published 2025-08-01“…The array allowed simultaneous mapping of cross-reactivity, a key advantage over conventional ELISA workflows.DiscussionOur findings confirm that protein-based microarrays offer a robust, efficient platform for antibody pair selection, reducing reagent use while accelerating assay development. …”
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Possibility of the Use of Public Microarray Database for Identifying Significant Genes Associated with Oral Squamous Cell Carcinoma
Published 2012-03-01“…Most of them were published in previous studies as cancer-related genes. From these selected genes, significant genetic pathways associated with expression changes were identified. …”
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Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer
Published 2015-01-01“…Using carbohydrate microarrays, we explored potential natural ligands of antitumor monoclonal antibody HAE3. …”
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IDENTIFYING IMPORTANT GENES IN OVARIAN CANCER FROM HIGH-DIMENSIONAL MICROARRAY DATA USING SIFS-CART METHOD
Published 2024-07-01“…Ovarian cancer can be identified from microarray data using machine learning. Many studies only focus on improving the machine learning classification algorithms to achieve higher performance. …”
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