Comparative analysis of hybrid-SNP microarray and nanopore sequencing for detection of large-sized copy number variants in the human genome by Catarina Silva, José Ferrão, Bárbara Marques, Sónia Pedro, Hildeberto Correia, Ana Valente, António Sebastião Rodrigues, Luís Vieira

“…In this work, we used nanopore sequencing technology to sequence 2 human cell lines at low depth of coverage to call copy number variations (CNV), and compared the results variant by variant with chromosomal microarray (CMA) results. Results We analysed sequencing data using CuteSV and Sniffles2 variant callers, compared breakpoints based on hybrid-SNP microarray, nanopore sequencing and Sanger sequencing, and analysed CNV coverage. …”
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Case of 7p22.1 Microduplication Detected by Whole Genome Microarray (REVEAL) in Workup of Child Diagnosed with Autism by Veronica Goitia, Marcial Oquendo, Robert Stratton

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Robust molecular subgrouping and reference-free aneuploidy detection in medulloblastoma using low-depth whole genome bisulfite sequencing by Dean Thompson, Jemma Castle, Martin Sill, Stefan M. Pfister, Simon Bailey, Debbie Hicks, Steven C. Clifford, Edward C. Schwalbe

“…We further assessed and optimised reference-free aneuploidy detection using low-pass WGBS and assessed concordance with microarray-derived calls. …”
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Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report by Onyinye O. Okonkwo, Veronica Ortega, Sheila Kane, Galina Aldrete, Paulina Ramirez, Philip T. Valente, Gopalrao V.N. Velagaleti

“…High-resolution SNP microarray studies detected whole genome uniparental isodisomy. …”
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Expression of long non-coding RNA in patients with non-IgA mesangial proliferative glomerulonephritis by CONG Shan, SUI Wei-guo, ZOU Gui-mian, XUE Wen, LI Huan, YAN Qiang, CHEN Jie-jing, LUO Ya-dan, CHEN Huai-zhou

“…Objective To study differential expression profile of mRNA and long non-coding RNA(IncRNA) through microarray analysis between non-IgA mesangial proliferative glomerulonephritis(MsPGN) patients and the controls,and then explore the potential role of IncRNA in the pathogenesis of non-IgA MsPGN.Methods Through simple random sampling,4 patients with non-IgA MsPGN and 2 controls were selected as disease group and control group,respectively.Renal cortical tissues from two groups were collected.Total RNA was extracted,quantified and prepared to ds-cDNA through reverse transcription ds-cDNA was labeled with NimbleGen one-color DNA labeling kit and used for array hybridization.All experimental data were processed through GO analysis,Pathway analysis and the gene loci correlation analysis of mRNA and IncRNA.Some IncRNAs that were closely related to non-IgA MsPGN were screened out.Finally,part of the array results was detected by PCR to verify the reliability of array test Results By fold change filtering,4317 differentially expressed mRNAs and 3502 differentially expressed IncRNAs were screened out.Five IncRNAs were found to play potential roles in the pathogenesis of non-IgA MsPGN:AF1180924(close to coding gene FGG),AK092233(close to coding gene COL18A1),AK130579(close to coding gene CREBBP),AK023598(close to coding gene LEPR),and AK055915(close to coding gene CDC42EP3).These results provided an important basis for revealing the pathogenesis of non-IgA MsPGN.Conclusions Some IncRNAs can potentially regulate related genes and plays an important role in the pathogenesis and development of non-IgA MsPGN.…”
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Gene selection based on adaptive neighborhood-preserving multi-objective particle swarm optimization by Sumet Mehta, Fei Han, Muhammad Sohail, Bhekisipho Twala, Asad Ullah, Fasee Ullah, Arfat Ahmad Khan, Qinghua Ling

Subjects: “…Microarray gene selection…”
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Optimized T7 Amplification System for Microarray Analysis by C. Pabón, Z. Modrusan, M.V. Ruvolo, I.M. Coleman, S. Daniel, H. Yue, L.J. Arnold, M.A. Reynolds

“…Glass cDNA microarray technologies offer a highly parallel approach for profiling expressed gene sequences in disease-relevant tissues. …”
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A two stage grading approach for feature selection and classification of microarray data using Pareto based feature ranking techniques: A case study by Rasmita Dash

“…High dimensional search space in microarray data with large number of genes and few dozen of samples increases the complexity of analysis of such databases. …”
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Evaluating the Nuclear Reaction Optimization (NRO) Algorithm for Gene Selection in Cancer Classification by Shahad Alkamli, Hala Alshamlan

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Analysis of a Series of 26 Cases With Prenatal Skeletal Dysplasia via Multiplatform Genetic Detection by Li‐min Cui, Hua‐ying Hu, Xiao‐mei Zhai, Ming‐fei Qi, Yan‐ming Liu, Cong‐ying Han, Jing Zhang, Ming Shen, Yu‐lan Xiang, Wen‐qi Chen, Kai Yang, Dong‐liang Zhang, Huan‐xia Xing

“…Materials and Methods In this study, we recruited 26 cases of SD and analyzed them with a designed sequential genetic detection. Chromosome karyotyping, microarray analysis (CMA), and whole exome sequencing (WES) techniques are performed as needed. …”
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DurdusTools—An Online Genetic Distance Calculation Tool for Efficient Variety Testing in Durum Wheat (<i>Triticum turgidum</i> L. subsp. <i>durum</i> (Desf.) Husn.) by Alexandra Ribarits, Svenja Bomers, Tadej Zerak, Oliver Alber, Jakob Seereiter, Antonio Escolano García, Ana Lázaro Somoza, Anna Pia Maria Giulini, Ferenc Somogyi, Sándor Kőrösi, Jutta Taferner-Kriegl

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Fast Spot Locating for Low-Density DNA Microarray by MinGin Kim, Jongwon Kim, Sun-Hee Kim, Jong-Dae Kim

“…Low-density DNA microarrays are crucial in molecular diagnostics due to their cost-effectiveness and high sensitivity. …”
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Microarray-Based Cancer Diagnosis with Artificial Neural Networks by Markus Ringnér, Carsten Peterson

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Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes by Douglas Ruben Call, Darrell P. Chandler, Fred Brockman

“…Microarrays printed on glass slides are often constructed by covalently linking oligonucleotide probes to a derivatized surface. …”
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Listen to genes: dealing with microarray data in the frequency domain. by Jianfeng Feng, Dongyun Yi, Ritesh Krishna, Shuixia Guo, Vicky Buchanan-Wollaston

“…<h4>Background</h4>We present a novel and systematic approach to analyze temporal microarray data. The approach includes normalization, clustering and network analysis of genes.…”
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P685: A single-center reevaluation and reanalysis of copy number variants of uncertain significance detected by chromosome microarray from consecutive pediatric patients by Wenjiao Li, Hongyan Chai, Autumn Diadamo, Yuan Dai, Peining Li, Michele Spencer-Manzon, Hui Zhang, Jiadi Wen

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Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder by Medhasi S, Pasomsub E, Vanwong N, Ngamsamut N, Puangpetch A, Chamnanphon M, Hongkaew Y, Limsila P, Pinthong D, Sukasem C

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A Sensitive and Fast microRNA Detection Platform Based on CRlSPR-Cas12a Coupled with Hybridization Chain Reaction and Photonic Crystal Microarray by Bingjie Xue, Bokang Qiao, Lixin Jia, Jimei Chi, Meng Su, Yanlin Song, Jie Du

“…The sensitive and fast detection of miRNAs is critical for diagnosis and prognosis. …”
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Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities by Yun Guo, Xiaoqin Xin, Linju Zhou, Jungao Huang

“…Chromosome microarray analysis detected abnormalities in 6.58% (5/76) of the isolated cardiac abnormalities group and 27.27% (6/22) in the group with combined abnormalities, showing a significant statistical difference (P &lt; 0.05). …”
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Computer Vision for Substrate Detection in High‐Throughput Biomaterial Screens Using Bright‐Field Microscopy by Robert Owen, Aishah Nasir, Mahetab H. Amer, Chenxue Nie, Xuan Xue, Laurence Burroughs, Chris Denning, Ricky D. Wildman, Faraz A. Khan, Morgan R. Alexander, Felicity R. A. J. Rose

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