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Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Bra...
Published 2016-01-01“…Changes in gene expression (microarray and qPCR) were assessed in the cingulate cortex. …”
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462
Improvement in Wrinkles by a Fairy Chemical, 2-Aza-8-oxohypoxanthine
Published 2025-06-01“…2-aza-8-oxohypoxanthine (AOH) has been shown to improve skin barrier function according to DNA microarray studies of normal human epidermal keratinocytes. …”
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463
Androgen Modulates Functions of Endothelial Progenitor Cells through Activated Egr1 Signaling
Published 2016-01-01“…Researches show that androgens have important effects on migration of endothelial cells and endothelial protection in coronary heart disease. …”
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464
Identification and analysis of neutrophil extracellular trap-related genes in periodontitis via bioinformatics and experimental verification
Published 2025-08-01“…Methods The microarray datasets were obtained from the Gene Expression Omnibus (GEO) database. …”
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465
Upregulated Acute Systemic Inflammation-Related Genes based on Endotoxin Exposure Provide “Survival Benefit” or Create “High Risk of Death” in Leukaemia and Colon Cancer
Published 2024-12-01“…In our study, survival analysis was performed to determine whether the upregulated genes triggered by endotoxins have hazardous effects on cancers or provide a survival benefit. …”
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466
Identification of RNA-binding protein genes associated with renal rejection and graft survival
Published 2024-12-01“…The aim of this study was to comprehensively analyze the expression of RPBs in renal rejection and use it to construct a robust prediction strategy for long-term graft survival. The microarray expression profiles used in this study were obtained from GEO database. …”
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467
Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana.
Published 2015-08-01“…When overlaying the PAPS1-dependent effects observed here with coexpression analysis based on independent microarray data, the two clusters of transcripts that are most closely coexpressed with PAPS1 show the strongest change in poly(A)-tail length and transcript abundance in paps1 mutants in our analysis. …”
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468
Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.
Published 2014-01-01“…The members of the SphR transcriptome were identified by microarray analyses, and DNA binding assays showed specific interaction of these promoters with SphR, which enabled us to determine the consensus SphR binding site. …”
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469
MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands.
Published 2014-01-01“…Thus, this study provides a detailed description of the effect of MyD88 deficiency on expression of several salivary antimicrobial factors in mice, illustrating the role for MyD88-mediated signaling in the innate immune defense in the oral cavity.…”
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470
Bioinformatics analysis of potential targets influencing the prognosis of OSCC
Published 2024-06-01“…[Objective:] To apply bioinformatics technology to screen differentially expressed genes (DEGs) in oral squamous cell carcinoma (OSCC) microarray data to further predict potential targets and prognostic genes. …”
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471
ODSEI Chip: An Open 3D Microfluidic Platform for Studying Tumor Spheroid‐Endothelial Interactions
Published 2025-04-01“…Herein, a novel open 3D‐microarray platform is presented for a spheroid‐endothelium interaction (ODSEI) chip, capable of arraying more than 1000 spheroids on top of the vasculature, compartmentalized for single spheroid‐level analysis of drug resistance, and allows for the extraction of specific spheroids for further analysis. …”
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472
RETRACTED ARTICLE: Molecular mechanism and diagnostic marker investigation of endoplasmic reticulum stress on periodontitis
Published 2023-03-01“…Methods The differentially expressed ERSGs (DE-ERSGs) were reveled based on periodontitis-related microarray dataset in Gene Expression Omnibus (GEO) database and 295 ERS in previous study, followed by a protein–protein interaction network construction. …”
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473
Extracellular vesicle-packaged miR-4253 secreted by cancer-associated fibroblasts facilitates cell proliferation in gastric cancer by inducing macrophage M2 polarization
Published 2024-12-01“…Here, we investigated the effect of CAF-EVs on macrophage polarization in GC and the underlying mechanisms. …”
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474
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction.
Published 2009-12-01“…We investigated the transcriptional changes that occur during endothelial differentiation of hESCs using whole genome microarray, and compared to human umbilical vein endothelial cells (HUVECs). …”
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475
Polymorphisms in the mitochondrial DNA control region and frailty in older adults.
Published 2010-06-01“…At baseline, frailty was identified as the presence of three or more of five indicators (weakness, slowness, shrinking, low physical activity, and exhaustion). mtDNA variation was assessed in a pilot study, including 315 individuals selected as extremes of the frailty phenotype, using an oligonucleotide sequencing microarray based on the Revised Cambridge Reference Sequence. …”
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476
Exploring Flexible Penalization of Bayesian Survival Analysis Using Beta Process Prior for Baseline Hazard
Published 2025-01-01“…Moreover, in microarray research, it is common to identify groupings of genes involved in the same biological pathways. …”
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477
The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription
Published 2016-01-01“…MFISH and CGH revealed distinct instability of chromosome structure in RKO. Gene expression microarray of RKO versus 7 colon cancer lines (with active Wnt signaling) and 3 normal specimens revealed 611 differentially expressed genes. …”
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478
ZNF37A downregulation promotes TNFRSF6B expression and leads to therapeutic resistance to concurrent chemoradiotherapy in rectal cancer patients
Published 2025-01-01“…The identification a signature comprising a group of genes as markers of cancer response to chemoradiotherapy would be more appropriate and effective for predicting chemoradiotherapy efficacy. …”
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479
R-locus for roaned coat is associated with a tandem duplication in an intronic region of USH2A in dogs and also contributes to Dalmatian spotting.
Published 2021-01-01“…We identified a putative causal variant in this region, an 11-kb tandem duplication (11,131,835-11,143,237) characterized by sequence read coverage and discordant reads of whole-genome sequence data, microarray probe intensity data, and a duplication-specific PCR assay. …”
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480
Exploration of the shared pathways and common biomarkers in cervical and ovarian cancer using integrated bioinformatics analysis
Published 2024-12-01“…Abstract Objective Searching for potential biomarkers and therapeutic targets for early diagnosis of gynecological tumors to improve patient survival. Methods Microarray datasets of cervical cancer (CC) and ovarian cancer (OC) were downloaded from the Gene Expression Omnibus (GEO) database, then, differential gene expression between cancerous and normal tissues in the datasets was analyzed. …”
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