Identification and Validation of a Potential Marker of Tissue Quality Using Gene Expression Analysis of Human Colorectal Tissue. by Nicole Lange, Florian T Unger, Monika Schöppler, Katja Pursche, Hartmut Juhl, Kerstin A David

“…Normal colorectal tissue and CRC tissue was analyzed using microarray and quantitative real-time PCR (qPCR). Comparing changes in gene expression between pre- and post-surgical tissue using microarray analysis identified a list of potential tissue quality biomarkers and this list was validated using qPCR. …”
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Renal tissue thawed for 30 minutes is still suitable for gene expression analysis. by Yi Ma, Xiao-Nan Kang, Wen-Bin Ding, Hao-Zheng Yang, Ye Wang, Jin Zhang, Yi-Ran Huang, Hui-Li Dai

“…We aim to evaluate the effects of thawing at room temperature for different time periods on gene expression analysis. …”
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AgileMultiIdeogram: Rapid Identification and Visualization of Autozygous Regions Using Illumina Short-Read Sequencing Data by Christopher M. Watson, Carolina Lascelles, Morag Raynor, Marilena Elpidorou, Ummey Hany, Laura Crinnion, Colin A. Johnson, Eamonn Sheridan, Alexander F. Markham, James A. Poulter, David T. Bonthron, Ian M. Carr

“…A well-established and effective way of identifying these “autozygous” genomic regions has been to search for runs of homozygous genotypes in microarray SNP data. …”
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Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature by James Wood, Stuart J. Smith, Marcos Castellanos-Uribe, Anbarasu Lourdusamy, Sean T. May, David A. Barrett, Richard G. Grundy, Dong-Hyun Kim, Ruman Rahman

“…Here, we use liquid chromatography–mass spectrometry and gene expression microarray to profile integrated intratumour metabolic heterogeneity, as a direct functional readout of adaptive responses of subclones to the tumour microenvironment. …”
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The absolute number of T lymphocyte subsets is beneficial for differential diagnosis of myelodysplastic syndrome with pure red cell aplastic anemia: a case report and review of the... by Liangjun Zhang, Huixiu Zhong

“…The result of the morphological examination of bone marrow, whole-genome microarray, and bone marrow biopsy all supported the diagnosis of MDS at the first clinical diagnosis. …”
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The expression levels of CYP3A4 and CYP3A5 serve as potential prognostic biomarkers in lung adenocarcinoma by Mao Qixing, Xu Juqing, Wang Yajing, Dong Gaochao, Xia Wenjie, Shi Run, Wang Anpeng, Xu Lin, Jiang Feng, Wang Jun

“…Lung adenocarcinoma remains to be a high-mortality disease with few effective prognostic biomarkers. Novel biomarkers are urgently demanded to supplement the current prognostic biomarkers. …”
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Profiling of Circulating Cell-free DNA Methylation Patterns Identifies Aberrant Methylated CTBP1 Promotor Sites for Prediction of Alzheimer’s Disease by Zhiwu Dong, Kewen Zhao, Hongjun Gu, Wenwei Yang, Xin Zhang

“…The R Bioconductor Linear Models for Microarray Data (LIMMA) package was employed to identify methylation variable positions (MVPs), and Probe Lasso was used to pinpoint differentially methylated regions (DMRs) linked to AD. …”
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Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea by Jiuhuang Lan, Yuhui Wang, Chang Liu, Hongli Chen, Qingshi Chen

“…Methods Firstly, the expression profiles of m6A-modified circRNA in left ventricular tissue of the CIH mouse model were examined using circRNA microarray analysis. Then, the expression level of selected circrRNA was compared by folding change filtration, and the consistency between them and microarray results was verified by MeRIP-qPCR. …”
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RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats. by B Alex Merrick, Dhiral P Phadke, Scott S Auerbach, Deepak Mav, Suzy M Stiegelmeyer, Ruchir R Shah, Raymond R Tice

“…Deep sequencing was used to investigate the subchronic effects of 1 ppm aflatoxin B1 (AFB1), a potent hepatocarcinogen, on the male rat liver transcriptome prior to onset of histopathological lesions or tumors. …”
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SLEPR: a sample-level enrichment-based pathway ranking method -- seeking biological themes through pathway-level consistency. by Ming Yi, Robert M Stephens

“…Analysis of microarray and other high throughput data often involves identification of genes consistently up or down-regulated across samples as the first step in extraction of biological meaning. …”
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An enhanced single base extension technique for the analysis of complex viral populations. by Dale R Webster, Armin G Hekele, Adam S Lauring, Kael F Fischer, Hao Li, Raul Andino, Joseph L DeRisi

“…This single base extension (SBE) based microarray platform was designed and optimized using poliovirus as the target genotype, but can be easily adapted to assay populations derived from any organism. …”
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HIF-1 inhibition reverses opacity in a rat model of galactose-induced cataract. by Masaru Takashima, Masaya Nagaya, Yoshihiro Takamura, Masaru Inatani, Masaya Oki

“…The detailed mechanism of cataract development has not been characterized, and effective drug therapies remain unavailable. Here, we investigated the effects of Hypoxia-inducible factor 1 (HIF-1) inhibitors using an ex vivo model, in which rat lenses were cultured in galactose-containing medium to induce opacity formation. …”
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Determination of Viral Nucleic Acid in the Human Blood by M. A. Abdurashitov, N. A. Netesova

“…Methods such as in situ hybridization, reverse transcription reaction (RT-PCR), nested PCR, multiplex PCR, as well as DNA microarray technology, and the method of massive parallel sequencing are considered in detail. …”
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Discovering structural cis‐regulatory elements by modeling the behaviors of mRNAs by Barrett C Foat, Gary D Stormo

“…We applied our structural cis‐regulatory element detector (StructRED) to microarray and mRNA sequence data from Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens. …”
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Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis by Gaoyan Tang, Xuelei Cao, Jiaqi Chen, Fu Hui, Na Xu, Yiqing Jiang, Hongmin Lu, Haifeng Xiao, Xiuming Liang, Mingzhe Ma, Yu Qian, Dongli Liu, Zhenlu Wang, Shuzhen Liu, Guohua Yu, Lei Sun

“…Furthermore, immunohistochemical (IHC) analysis of an NSCLC tissue microarray confirmed a strong positive correlation between p-p38 and NOXA expression. …”
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Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells. by Swojani Shrestha, Sandeep Singhal, Donald A Sens, Seema Somji, Bethany A Davis, Rachel Guyer, Spencer Breen, Matthew Kalonick, Scott H Garrett

“…The results validated the microarray analysis, which showed a significant decrease in the mRNA as well as protein expression of the selected genes as the concentration of glucose increased. …”
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Prediction of gene expression in embryonic structures of Drosophila melanogaster. by Anastasia A Samsonova, Mahesan Niranjan, Steven Russell, Alvis Brazma

“…The use of high-throughput approaches, such as large-scale in situ hybridisation and genome-wide expression profiling via DNA microarrays, is beginning to provide insights into the complexities of development. …”
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Synchrotron Radiation-Induced X-Ray Emission to Identify Metal Ions in Preparations of Purified Protein by Thomas Pfister, Huan Feng, Eckard Wimmer, Keith W. Jones

“…Thus, SRIXE may have wide use as a particularly effective method for rapidly determining trace metals in microarray samples.…”
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Development of HuMiChip for functional profiling of human microbiomes. by Qichao Tu, Zhili He, Yan Li, Yanfei Chen, Ye Deng, Lu Lin, Christopher L Hemme, Tong Yuan, Joy D Van Nostrand, Liyou Wu, Xuedong Zhou, Wenyuan Shi, Lanjuan Li, Jian Xu, Jizhong Zhou

“…Here we have developed a functional gene-based microarray for profiling human microbiomes (HuMiChip) with 36,802 probes targeting 50,007 protein coding sequences for 139 key functional gene families. …”
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Comparison of eleven methods for genomic DNA extraction suitable for large-scale whole-genome genotyping and long-term DNA banking using blood samples. by Androniki Psifidi, Chrysostomos I Dovas, Georgios Bramis, Thomai Lazou, Claire L Russel, Georgios Arsenos, Georgios Banos

“…Over the recent years, next generation sequencing and microarray technologies have revolutionized scientific research with their applications to high-throughput analysis of biological systems. …”
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