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Consistency and Stability in Feature Selection for High-Dimensional Microarray Survival Data in Diffuse Large B-Cell Lymphoma Cancer
Published 2025-02-01“…High-dimensional survival data, such as microarray datasets, present significant challenges in variable selection and model performance due to their complexity and dimensionality. …”
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Optimization based tumor classification from microarray gene expression data.
Published 2011-02-01“…<h4>Background</h4>An important use of data obtained from microarray measurements is the classification of tumor types with respect to genes that are either up or down regulated in specific cancer types. …”
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Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium
Published 2025-01-01“…All strains demonstrated effective straw biomass degradation compared to the negative control, with significant differences detected only in oil seed rape straw biodegradation estimations. …”
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CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Published 2024-11-01“…We used CRISPR screens to uncover the expanded network of genes controlling high mannose levels, followed by lectin microarrays to fully measure the complex effect of select regulators on glycosylation globally. …”
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Machine learning identification of molecular targets for medulloblastoma subgroups using microarray gene fingerprint analysis
Published 2025-01-01“…The classification achieved an average accuracy of 96%, demonstrating the effectiveness of the proposed approach. Feature selection using the Kruskal–Wallis and χ2 tests revealed statistically relevant genes contributing to subgroup discrimination. …”
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Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment
Published 2010-09-01“…Conclusions: This hybridization array presents an accurate and cost-effective method for evaluating the disease-causing potential of Salmonella in outbreak investigations by targeting a selective set of Salmonella-associated virulence genes. …”
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Ensemble Algorithm Based on Gene Selection, Data Augmentation, and Boosting Approaches for Ovarian Cancer Classification
Published 2024-12-01“…<b>Background:</b> Ovarian cancer is a difficult and lethal illness that requires early detection and precise classification for effective therapy. Microarray technology has permitted the simultaneous assessment of hundreds of genes’ expression levels, yielding important insights into the molecular pathways driving ovarian cancer. …”
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BIMSSA: enhancing cancer prediction with salp swarm optimization and ensemble machine learning approaches
Published 2025-01-01“…The BIMSSA model implements a pipelined feature selection method to effectively handle high-dimensional microarray data. …”
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Evaluating the Nuclear Reaction Optimization (NRO) Algorithm for Gene Selection in Cancer Classification
Published 2025-04-01“…This complexity necessitates advanced optimization methods for effective gene selection. <b>Methods</b>: This study introduces and evaluates the Nuclear Reaction Optimization (NRO)—drawing inspiration from nuclear fission and fusion—for identifying informative gene subsets in six benchmark cancer microarray datasets. …”
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A hybrid of an automated multi-filter with a spatial bound particle swarm optimization for gene selection and cancer classification
Published 2025-03-01“…Therefore, early detection of cancer is critical for effective treatments. However, the main challenge in disease identification and classification, such as cancer microarray dataset, is the large number of genes. …”
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Silver coated porous silicon microarray SERS platform for detecting aflatoxin B1 fumonisin B1 and ochratoxin A
Published 2025-08-01“…Herein, we present a newly developed nanostructured microarray based on silver-coated porous silicon (Ag-pSi) used as a surface-enhanced Raman scattering (SERS) transducer. …”
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A Network Analysis Approach to Detect and Differentiate Usher Syndrome Types Using miRNA Expression Profiles: A Pilot Study
Published 2024-11-01“…<b>Methods:</b> We collected microarray miRNA-expression data from 17 samples, representing four patient-derived USH cell lines and a non-USH control. …”
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Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma
Published 2025-01-01“…Specifically, we quantified the serological AAb profiles of 94 PDAC, chronic pancreatitis (CP), other pancreatic- (PC) and prostate cancers (PRC), non-ulcer dyspepsia patients (DYS), and healthy controls (HC).ResultsCombinatorial ROC curve analysis on the training cohort data from the cancer antigen microarrays identified the most effective biomarker combination as CEACAM1-DPPA2-DPPA3-MAGEA4-SRC-TPBG-XAGE3 with an AUC = 85·0% (SE = 0·828, SP = 0·684). …”
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Generalizability of machine learning models for diabetes detection a study with nordic islet transplant and PIMA datasets
Published 2025-02-01“…Abstract Diabetes Mellitus (DM) is a global health challenge, and accurate early detection is critical for effective management. The study explores the potential of machine learning for improved diabetes prediction using microarray gene expression data and PIMA data set. …”
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LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancer
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Identification of three small nucleolar RNAs (snoRNAs) as potential prognostic markers in diffuse large B‐cell lymphoma
Published 2023-02-01“…Results Twelve prognosis‐correlated snoRNAs were selected from the DLBCL patient cohort of microarray profiles, and a three‐snoRNA signature consisting of SNORD1A, SNORA60, and SNORA66 was constructed. …”
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Using effective subnetworks to predict selected properties of gene networks.
Published 2010-10-01“…Steady state measurements of these influence networks can be obtained from DNA microarray experiments. However, since they contain a large number of nodes, the computation of influence networks requires a prohibitively large set of microarray experiments. …”
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