Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing. by Amy Longtin, Marina M Watowich, Baptiste Sadoughi, Rachel M Petersen, Sarah F Brosnan, Kenneth Buetow, Qiuyin Cai, Cayo Biobank Research Unit, Michael D Gurven, James P Higham, Heather M Highland, Yi-Ting Huang, Hillard Kaplan, Thomas S Kraft, Yvonne A L Lim, Jirong Long, Amanda D Melin, Michael J Montague, Jamie Roberson, Kee Seong Ng, Michael L Platt, India A Schneider-Crease, Jonathan Stieglitz, Benjamin C Trumble, Vivek V Venkataraman, Ian J Wallace, Jie Wu, Noah Snyder-Mackler, Angela Jones, Alexander G Bick, Amanda J Lea

“…While costs are decreasing, whole-genome DNA methylation profiling remains prohibitively expensive for most population-scale studies, creating a need for cost-effective, reduced representation approaches (i.e., assays that rely on microarrays, enzyme digests, or sequence capture to target a subset of the genome). …”
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Generalizability of machine learning models for diabetes detection a study with nordic islet transplant and PIMA datasets by Dinesh Chellappan, Harikumar Rajaguru

“…Abstract Diabetes Mellitus (DM) is a global health challenge, and accurate early detection is critical for effective management. The study explores the potential of machine learning for improved diabetes prediction using microarray gene expression data and PIMA data set. …”
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Genetic Comparison and Selection of Reproductive and Growth-Related Traits in Qinchuan Cattle and Two Belgian Cattle Breeds by Xiaopeng Li, Peng Niu, Xueyan Wang, Fei Huang, Jieru Wang, Huimin Qu, Chunmei Han, Qinghua Gao

“…A total of 270 Belgian cattle (91 BR and 179 BWR) and 286 Qinchuan cattle were genotyped using the Illumina Bovine SNP 50K microarray. Data analysis was conducted using PLINK and Beagle 5.1 to estimate linkage disequilibrium (LD) and effective population size (Ne). …”
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HEREDITARY DISEASES AND SYNDROMES ACCOMPANIED BY FEBRILE CONVULSIONS: CLINICAL AND GENETIC CHARACTERISTICS AND DIAGNOSTIC PROCEDURES by E. L. Dadali, A. A. Sharkov, I. V. Sharkova, I. V. Kanivets, F. A. Konovalov, I. A. Akimova

“…It also determines the significance of using a chromosomal microarray analysis to diagnose both chromosomal and monogenic diseases accompanied by convulsions.…”
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Utilizing Machine Learning Techniques for Cancer Prediction and Classification based on Gene Expression Data by Mariwan Mahmood Hama Aziz, Sozan Abdullah Mahmood

“…Detecting cancer early by examining gene expression data is vital for providing effective patient care. Each sample in the Gene dataset usually includes a range of features, each representing a specific gene. …”
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The antioxidant stress effect of granulin precursor in vitiligo by Haoran Guo, Jing Chen, Ling Jiang

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Effects of tumour-associated macrophages on cardia carcinoma progression by Zhixiong Zhang, Zihong Xu, Yaowu Cai, Xintong Chen, Chaoqing Huang, Xuefeng Xu

“…The THP-1 monocyte cell line was used to induce differentiation into M2-type TAMs, co-cultured with gastric cancer cell lines AGS and MKN-45, and the effect of TAMs on the invasive ability of gastric cancer cells was detected by Transwell assay. …”
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Prognostic effect of immunohistochemically determined molecular subtypes in gastric cancer by Jefim Brodkin, Tuomas Kaprio, Jaana Hagström, Alli Leppä, Arto Kokkola, Caj Haglund, Camilla Böckelman

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Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni. by Enyara R Morais, Katia C Oliveira, Renato G de Paula, Alice M M Ornelas, Érika B C Moreira, Fernanda Rafacho Badoco, Lizandra G Magalhães, Sergio Verjovski-Almeida, Vanderlei Rodrigues

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Effects of matrix metalloproteinase inhibition in cultured human Tenon’s capsule fibroblasts by Na Hyun Kim, Kyung Eun Han, Roo Min Jun, Seongsoo Sohn, Changwon Kee, Wool Suh

“…Abstract Background This study aimed to compare the characteristics of anterior and posterior human Tenon’s capsule fibroblasts and determine the effect of matrix metalloproteinase (MMP) inhibition on cultured human Tenon’s capsule fibroblasts. …”
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Effects of long-term pioglitazone treatment on peripheral and central markers of aging. by Eric M Blalock, Jeremiah T Phelps, Tristano Pancani, James L Searcy, Katie L Anderson, John C Gant, Jelena Popovic, Margarita G Avdiushko, Don A Cohen, Kuey-Chu Chen, Nada M Porter, Olivier Thibault

“…Finally, a combination of microarray analyses on hippocampal tissue and serum-based multiplex cytokine assays revealed that age-dependent inflammatory increases were not reversed by PIO.…”
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Effect of Huangqin Tang on Colonic Gene Expression in Rats with Ulcerative Colitis by Dunfang Wang, KaiFeng Shi, Yanli Wang, Dixin Zou, Shanshan Guo, Tao Li, Hangyu Xu, Xuran Ma, JiaXing Liu, HongXin Song, Weipeng Yang, Yu Li

“…After a ten-day treatment, microarray analysis was performed from the colon segment of the rats. …”
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Effects of pregnancy on breast cancer immunology: immune biomarker and TIL quantification by Kristin Galas, Moritz Gleitsmann, Julia Rey, Christine Solbach, Isabell Witzel, Thomas Karn, Sabine Schmatloch, Christian Schem, Andreas Schneeweis, Bruno Sinn, Tanja Fehm, Carsten Denkert, Peter Fasching, Anne-Sophie Litmeyer, Frederik Marmé, Paul Jank, Volkmar Müller, Sabine Seiler, Elmar Stickeler, Olaf Ortmann, Marion van Mackelenbergh, Valentina Nekljudova, Johannes Holtschmidt, Sibylle Loibl

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iCLIP predicts the dual splicing effects of TIA-RNA interactions. by Zhen Wang, Melis Kayikci, Michael Briese, Kathi Zarnack, Nicholas M Luscombe, Gregor Rot, Blaž Zupan, Tomaž Curk, Jernej Ule

“…Binding downstream of 5' splice sites was used to predict the effects of TIA proteins in enhancing inclusion of proximal exons and silencing inclusion of distal exons. …”
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Lack of effect of the Salmonella deubiquitinase SseL on the NF-κB pathway. by Francisco S Mesquita, David W Holden, Nathalie Rolhion

“…To attempt to clarify these discrepancies, we compared mRNA levels in mouse primary bone marrow-derived macrophages infected with wild-type or sseL mutant strains using a genome-wide microarray. There was no detectable effect of loss of SseL on mRNA levels corresponding to any known NF-κB-regulated gene. …”
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Identification of the Exercise and Time Effects on Human Skeletal Muscle through Bioinformatics Methods by Mufang Feng, Jie Ji, Xiaoliu Li, Xinming Ye

“…Methods. To determine the effects of exercise and time on human skeletal muscle, we downloaded the microarray expression profile of GSE1832 and analyzed it to select differentially expressed genes (DEGs). …”
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Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells by Lara Pasovic, Jon Roger Eidet, Berit S. Brusletto, Torstein Lyberg, Tor P. Utheim

“…Total RNA was isolated and the gene expression profile was determined using DNA microarrays. Comparison of the microarray expression values with qRT-PCR analysis of selected genes validated the results. …”
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Treatment with Rhizoma Dioscoreae Extract Has Protective Effect on Osteopenia in Ovariectomized Rats by Zhiguo Zhang, Lihua Xiang, Dong Bai, Xiaowei Fu, Wenlai Wang, Yan Li, Hong Liu, Jinghua Pan, Ya’nan Li, Gary Guishan Xiao, Dahong Ju

“…The aims of this study were to evaluate the osteoprotective effect of aqueous extract from Rhizoma Dioscoreae (RDE) on rats with ovariectomy- (OVX-) induced osteopenia. …”
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Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells by Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu

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Silencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma by Dai J, Zhu T, Wan J, Liu R, Song Y, Zhang D, Wang X, Zhang H, Li W, Lin J, Zhu X, Liu Y

“…Furthermore, silencing NEDD4L could effectively inhibit the malignant behaviors of HCC. …”
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