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Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment
Published 2010-09-01“…The objective of this study is to demonstrate the use of a robust and inexpensive microarray platform to assay the virulence gene profiles in Salmonella from food and/or the food animal environment, and then use ArrayTrackTM for data analysis. …”
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Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray
Published 2015-01-01“…With the recent development of biotechnologies, cDNA microarray chips are increasingly applied in cancer research. …”
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Machine learning identification of molecular targets for medulloblastoma subgroups using microarray gene fingerprint analysis
Published 2025-01-01“…An artificial neural network (ANN) model trained on microarray gene expression data determined minimal gene combinations for each subgroup. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer
Published 2025-02-01“…Transfection efficiency was confirmed via qRT-PCR in HCT116 and SW480 colon cells, and the effects of circDOCK1 on cell proliferation, migration, and invasion were assessed.ResultsMicroarray data revealed 149 significantly differentially expressed circRNAs, including 71 upregulated and 78 downregulated circRNAs, in CRC tissues. …”
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Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Current research is focused on identifying effective treatments for PTSD. Advances in bioinformatics provide opportunities to elucidate the underlying mechanisms of PTSD. …”
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A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis.
Published 2016-01-01“…In the present study, we performed DNA microarray analysis to investigate the effects of a HP diet on the liver, which plays a pivotal role in energy metabolism. …”
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Development of a microarray based telomerase binding assay reveals unusual binding of a cytochalasin derivative
Published 2025-06-01“…In this study, we present a highly miniaturized, microarray-based assay designed to identify compounds that target telomerase. …”
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In Vitro Investigation of Statin Effects on Genes Associated with Severe COVID-19 in Cancerous and Non-Cancerous Cells
Published 2025-07-01“…However, statins exhibit additional pleiotropic effects. The present study aims to investigate the effects of all eight currently existing statins on the expression of genes whose products have been reported to be directly associated with complicated COVID-19 disease. …”
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Systematic spatial bias in DNA microarray hybridization is caused by probe spot position-dependent variability in lateral diffusion.
Published 2011-01-01“…Numerical simulations reveal a strong influence of microarray well geometry on the spatial bias.<h4>Conclusions</h4>Reciprocal adjustment of the size of the microarray hybridization chamber to the area of surface-bound probes is a simple and effective measure to minimize or eliminate the diffusion-based bias, resulting in increased uniformity and accuracy of quantitative DNA microarray hybridization.…”
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Gene Expression Profile of Dendritic Cell-Tumor Cell Hybrids Determined by Microarrays and Its Implications for Cancer Immunotherapy
Published 2015-01-01“…Dendritic cell- (DC-) tumor fusion cells stimulate effective in vivo antitumor responses. However, therapeutic approaches are dependent upon the coadministration of exogenous 3rd signals. …”
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Portable Fluorescence Microarray Reader-Enabled Biomarker Panel Detection System for Point-of-Care Diagnosis of Lupus Nephritis
Published 2025-01-01“…This study introduces an LED-based fluorescence reader designed for POC applications, enabling multiplex detection of lupus nephritis (LN) biomarkers using a biomarker microarray (BMA) slide. The reader integrates an LED excitation source, neutral density (ND) filters for precise intensity control, and onboard image processing with Gaussian smoothing and centroid thresholding to enhance signal detection and localization. …”
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Consistency and Stability in Feature Selection for High-Dimensional Microarray Survival Data in Diffuse Large B-Cell Lymphoma Cancer
Published 2025-02-01“…High-dimensional survival data, such as microarray datasets, present significant challenges in variable selection and model performance due to their complexity and dimensionality. …”
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Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses
Published 2025-04-01“…PD diagnosis depends on clinical manifestation of symptoms but is lack of effective biomarker.MethodsAvailable human microarray-based transcriptomic datasets of the substantia nigra and blood were acquired for PD cases and controls. …”
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CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray.
Published 2015-01-01“…Combined inhibition of a key complement component (C3 and C5) and TLR-co-receptor CD14 has been shown to attenuate certain systemic inflammatory responses. Using DNA microarray and gene annotation analyses, we aimed to decipher the effect of combined inhibition of C3 and CD14 on the transcriptional response to bacterial challenge in human whole blood. …”
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A microarray assessment of the modulation of human oxidative stress gene expression by rooibos and honeybush tea extracts in UVB-irradiated keratinocytes
Published 2025-06-01“…Microarray was used to investigate the expression of 84 oxidative stress response genes in response to rooibos and honeybush tea extracts and the effect of pre-exposure to extracts prior to UVB exposure was assessed. …”
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Silver coated porous silicon microarray SERS platform for detecting aflatoxin B1 fumonisin B1 and ochratoxin A
Published 2025-08-01“…Herein, we present a newly developed nanostructured microarray based on silver-coated porous silicon (Ag-pSi) used as a surface-enhanced Raman scattering (SERS) transducer. …”
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A Comparative Analysis of the Roles of von Willebrand Factor and ADAMTS13 in Hepatocellular Carcinoma: A Bioinformatics and Microarray-Based Study
Published 2025-04-01“…In this study, we aimed to investigate the effects of von Willebrand factor (VWF) and <i>ADAMTS13</i> on HCC prognosis, using bioinformatics tools. …”
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Robust molecular subgrouping and reference-free aneuploidy detection in medulloblastoma using low-depth whole genome bisulfite sequencing
Published 2025-06-01“…Specifically, whole-genome bisulfite sequencing (WGBS) enables assessment of genome-wide methylation status at single-base resolution, however its routine application has been limited by high DNA input requirements, cost, and a lack of pipelines tailored to more rapidly-acquired and cost-effective low-depth (< 10x) sequencing data. We utilised WGBS data for 69 medulloblastomas, comprising 35 in-house low-depth (~ 10x) and 34 publicly available high-depth (~ 30x) samples, alongside cerebellar controls (n = 8), all with matched DNA methylation microarray data. …”
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