The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A by Iwona Adwent, Beniamin Oskar Grabarek, Marta Kojs-Mrożkiewicz, Ryszard Brus, Rafał Staszkiewicz, Andrzej Plewka, Michał Stasiowski, Anita Lyssek-Boroń

“…The expression profile of mRNA related to TGFβ paths was indicated by microarray and RTqPCR analyses. The ELISA test was used to analyze changes on the proteome level. …”
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HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways by Hongliang Wang, Wei Xing, Shijie Tang, Zhenglin Wang, Tiantian Lv, Yan Wu, Shuzhen Guo, Chun Li, Jing Han, Ruixin Zhu, Wei Wang

“…HuoXueJieDu (HXJD) formula exerts protective effects against diabetic retinopathy (DR) in rats, but its underlying mechanism remains unknown. …”
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Fecal carriage of vanB antibiotic resistance gene affects adipose tissue function under vancomycin use by Lars M. M. Vliex, Giang N. Le, Marina Fassarella, Dorien Reijnders, Gijs H. Goossens, Erwin G. Zoetendal, John Penders, Ellen E. Blaak

“…Abdominal subcutaneous adipose tissue (AT) gene expression was assessed using Affymetrix microarray. Gut microbial composition was determined using the Human Intestinal Tract Chip (HITChip) microarray. …”
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Spheroid Culture of Mesenchymal Stem Cells by Zoe Cesarz, Kenichi Tamama

“…Mesenchymal stem cells (MSCs) cultured in spheroids have enhanced anti-inflammatory, angiogenic, and tissue reparative/regenerative effects with improved cell survival after transplantation. …”
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Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression by Cheng Dai, Bin Shen, Shenyan Liu, Cong Li, Shuqun Yang, Jie Wang, Jie Zhang, Manqi Liu, Zhixuan Zhu, Wan Shi, Qi Zhang, Zhui Chen, Nannan Zhang

“…Immunohistochemistry (IHC) was utilized to analyze human tissue microarray samples of osteosarcoma. We then investigated the anti-tumor effect and the mechanisms of action of pharmacologic inhibition of CSF-1R activity by pimicotinib (ABSK021), a highly potent and selective small molecule inhibitor of CSF-1R, in osteosarcoma models both in vitro and in vivo. …”
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RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis by S. M. Nuruzzaman Nobel, S M Masfequier Rahman Swapno, Md. Ashraful Hossain, Mejdl Safran, Sultan Alfarhood, Md. Mohsin Kabir, M. F. Mridha

“…The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. …”
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Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients by Yilun Tao, Yilun Tao, Hongzhi Guo, Dong Han, Miao Yang, Ting Lun, Lihong Wang, Wenxia Song, Haiwei Wang, Xiaoze Li

“…BackgroundDevelopmental delay (DD) and intellectual disability (ID) are prevalent in children and often have genetic causes, particularly copy number variations (CNVs). Chromosomal microarray analysis (CMA) and whole-exome sequencing (WES) are key diagnostic tools for identifying genetic contributions to these disorders. …”
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Identification of genes and pathways related to lymphovascular invasion in breast cancer patients: A bioinformatics analysis of gene expression profiles by Sukhontip Klahan, Henry Sung-Ching Wong, Shih-Hsin Tu, Wan-Hsuan Chou, Yan-Feng Zhang, Thien-Fiew Ho, Chih-Yi Liu, Shih-Ying Yih, Hsing Fang Lu, Sean Chun-Chang Chen, Chi-Cheng Huang, Wei-Chiao Chang

“…Surgery is the most effective treatment for breast cancer patients. However, some patients developed recurrence and distant metastasis after surgery. …”
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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. by Simon R Stockwell, Georgina Platt, S Elaine Barrie, Georgia Zoumpoulidou, Robert H Te Poele, G Wynne Aherne, Stuart C Wilson, Peter Sheldrake, Edward McDonald, Mathilde Venet, Christelle Soudy, Frédéric Elustondo, Laurent Rigoreau, Julian Blagg, Paul Workman, Michelle D Garrett, Sibylle Mittnacht

“…Transcriptional profiling by cDNA microarray combined with reverse genetics revealed phosphorylation of the eukaryotic initiation factor 2-alpha (EIF2A) through the eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3/PERK) as the mechanism of action of this compound. …”
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Genomic copy number variants: evidence for association with antibody response to anthrax vaccine adsorbed. by Michael I Falola, Howard W Wiener, Nathan E Wineinger, Gary R Cutter, Robert P Kimberly, Jeffrey C Edberg, Donna K Arnett, Richard A Kaslow, Jianming Tang, Sadeep Shrestha

“…Anthrax vaccine is highly effective, but vaccine-induced IgG antibody responses vary widely following required doses of vaccinations. …”
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Homeobox protein B6 and homeobox protein B8 control immune-cancer cell interactions in pancreatic cancer by Ludivine Bertonnier-Brouty, Sara Bsharat, Kavya Achanta, Jonas Andersson, Thanya Pranomphon, Tania Singh, Tuomas Kaprio, Jaana Hagström, Caj Haglund, Hanna Seppänen, Rashmi B. Prasad, Isabella Artner

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer lacking effective drugs and therefore new treatment targets are needed. …”
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Upregulation of RIG‐I is Critical for Responsiveness to IFN‐α Plus Anti‐PD‐1 in Colorectal Cancer by Haihang Nie, Shilin Fang, Rui Zhou, Yifan Jia, Jingkai Zhou, Yumei Ning, Yali Yu, Yuntian Hong, Fei Xu, Qiu Zhao, Jiayan Nie, Fan Wang

“…ABSTRACT Backgrounds Immunotherapy is a promising and effective approach that has achieved significant curative effects in colorectal cancer (CRC). …”
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Altered expression of miRNA profile in peripheral blood mononuclear cells following the third dose of inactivated COVID-19 vaccine by Guanguan Qiu, Ruoyang Zhang, Huifeng Qian, Ruoqiong Huang, Jie Xia, Ruoxi Zang, Zhenkai Le, Qiang Shu, Jianguo Xu, Guoping Zheng, Jiangmei Wang

“…COVID-19 vaccination is the most effective strategy for preventing severe disease and death. …”
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Mutation spectrum in epilepsy and seizure disorders in a group of Emirati patients: a retrospective cohort study and literature review by Aisha AlShamsi, Sema Koruturk

“…The genetic tests were performed based on the patient's clinical phenotypes and family history, and included chromosome microarray, targeted variant testing, next-generation sequencing, or whole-exome sequencing (solo or trio). …”
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USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway by Ni Xiong, Yue Wang, Junhong Jiang

“…Validation was conducted using tissue microarray (TMA) analysis and immunohistochemistry (IHC) to compare USP5 expression levels in HNSCC tissues versus adjacent normal tissues. …”
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Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury by Shijie Yang, Beibei Yu, Qing Zhang, Yongfeng Zhang, Longhui Fu, Bisheng Zhou, Haining Wu, Jianzhong Li, Shouping Gong

“…Methods We employed microarray and single-cell RNA sequencing (scRNA-seq) to investigate gene expression changes and immune cell dynamics in mice following crush injury at 3 and 7 days post-injury (dpi). …”
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Hypoxia alters the response of ovarian cancer cells to the mitomycin C drug by Aleksandra Gawrylak, Aleksandra Gawrylak, Klaudia Brodaczewska, Roksana Iwanicka-Nowicka, Roksana Iwanicka-Nowicka, Marta Koblowska, Marta Koblowska, Agnieszka Synowiec, Lubomir Bodnar, Lubomir Bodnar, Cezary Szczylik, Bogdan Lesyng, Rafał Stec, Claudine Kieda, Claudine Kieda

“…In this study, we show that mitomycin C (MMC), an antineoplastic antibiotic, is rarely used in ovarian cancer (OC) treatment despite its potential efficacy; we use MMC as an example of a treatment that warrants reevaluation under microenvironmental conditions, particularly during in vitro testing.MethodsTo evaluate the effects of MMC and oxygen tension (pO2) on OC cells (SKOV3), HTA 2.0 microarrays were used, which demonstrated that hypoxia and MMC induced transcriptomic changes in OC cells. …”
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Efficacy and tolerability of rufinamide in the treatment of epilepsy (experience of the Svt. Luka’s Institute of Child Neurology and Epilepsy) by K. Yu. Mukhin, O. A. Pylaeva, M. Yu. Bobylova, N. V. Freydkova, L. Yu. Glukhova, M. O. Abramov

“…Side effects were observed in 6 (19 %) participants. Side effects (forced normalization) caused withdrawal of rufinamide in 1 (3.2 %) patient. …”
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Transcriptional response to deletion of the phosphatidylserine decarboxylase Psd1p in the yeast Saccharomyces cerevisiae. by Martina Gsell, Gerald Mascher, Irmgard Schuiki, Birgit Ploier, Claudia Hrastnik, Günther Daum

“…To study the genome wide effect of an unbalanced cellular and mitochondrial PE level and in particular the contribution of Psd1p to this depletion we performed a DNA microarray analysis with a ∆psd1 deletion mutant. …”
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Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers. by Timothy Fee, Swetha Surianarayanan, Crawford Downs, Yong Zhou, Joel Berry

“…A microarray of cyotoskeleton regulators was probed to examine differences in gene expression between cells grown on an aligned and randomly oriented substrates. …”
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