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Utilizing Machine Learning Techniques for Cancer Prediction and Classification based on Gene Expression Data
Published 2025-06-01“…Lately, several studies have delved into cancer classification by leveraging data mining techniques, machine learning algorithms, and statistical methods to thoroughly analyze high-dimensional datasets. Detecting cancer early by examining gene expression data is vital for providing effective patient care. …”
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Genetic findings of children with congenital heart diseases using chromosomal microarray and trio-based whole exome sequencing
Published 2025-07-01“…In individuals with extracardiac features, the overall detection rate was significantly higher (61.5%) than in individuals with isolated CHD (17.3%) (P = 4.6 × 10− 3). …”
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103
Gene Expression Profile of Dendritic Cell-Tumor Cell Hybrids Determined by Microarrays and Its Implications for Cancer Immunotherapy
Published 2015-01-01“…Dendritic cell- (DC-) tumor fusion cells stimulate effective in vivo antitumor responses. However, therapeutic approaches are dependent upon the coadministration of exogenous 3rd signals. …”
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104
Deciphering the prokaryotic community and metabolisms in South African deep-mine biofilms through antibody microarrays and graph theory.
Published 2014-01-01“…Both culture-independent techniques coincided in detecting features related to aerobic sulfur-oxidizers, aerobic chemoorganotrophic Alphaproteobacteria and metanotrophic Gammaproteobacteria. 16S rRNA gene sequencing detected phylotypes related to nitrate-reducers and anaerobic sulfur-oxidizers, whereas the EMChip66 detected immunological features from methanogens and sulfate-reducers. …”
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105
A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases
Published 2025-01-01“…The diagnostic tests currently available for tick-borne diseases are severely limited in their ability to provide accurate results and cannot detect multiple pathogens in a single run. The multiplex protein microarray developed at Vibrant was designed to detect multiple serological antibodies thereby detecting exposure to multiple pathogens simultaneously. …”
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106
No Amplifications of Hypoxia-Inducible Factor-1α Gene in Invasive Breast Cancer: A Tissue Microarray Study
Published 2004-01-01“…Methods: Protein and gene expression of HIF‐1α were analyzed on a tissue microarray of 94 breast cancers by immunohistochemistry and fluorescent in situ hybridization (FISH), respectively. …”
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107
Consistency and Stability in Feature Selection for High-Dimensional Microarray Survival Data in Diffuse Large B-Cell Lymphoma Cancer
Published 2025-02-01“…High-dimensional survival data, such as microarray datasets, present significant challenges in variable selection and model performance due to their complexity and dimensionality. …”
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108
PD-L1 quantification across tumor types using the reverse phase protein microarray: implications for precision medicine
Published 2021-10-01“…Using a high throughput immunoassay, the reverse phase protein microarray (RPPA), coupled with a fluorescence-based detection system, this study compared the performance of six anti-PD-L1 antibody clones on 666 tumor samples.Methods PD-L1 expression was measured using five antibody clones (22C3, 28–8, CAL10, E1L3N and SP142) and the therapeutic antibody atezolizumab on 222 lung, 71 ovarian, 52 prostate and 267 breast cancers, and 54 metastatic lesions. …”
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109
Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses
Published 2025-04-01“…PD diagnosis depends on clinical manifestation of symptoms but is lack of effective biomarker.MethodsAvailable human microarray-based transcriptomic datasets of the substantia nigra and blood were acquired for PD cases and controls. …”
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Local Mean Normalization of Microarray Element Signal Intensities across an Array Surface: Quality Control and Correction of Spatially Systematic Artifacts
Published 2002-06-01“…Here we present a methodology for the normalization of element signal intensities to a mean intensity calculated locally across the surface of a DNA microarray. These methods allow the detection and/or correction of spatially systematic artifacts in microarray data. …”
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112
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray.
Published 2015-01-01“…Combined inhibition of a key complement component (C3 and C5) and TLR-co-receptor CD14 has been shown to attenuate certain systemic inflammatory responses. Using DNA microarray and gene annotation analyses, we aimed to decipher the effect of combined inhibition of C3 and CD14 on the transcriptional response to bacterial challenge in human whole blood. …”
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113
Prenatal diagnosis and molecular cytogenetic analysis of pure chromosome 10p15.3 microdeletion using chromosomal microarray analysis
Published 2024-12-01“…Karyotyping and chromosomal microarray analysis (CMA) was conducted to assess chromosomal abnormalities and detect copy number variations (CNVs) within the families, respectively. …”
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114
A microarray assessment of the modulation of human oxidative stress gene expression by rooibos and honeybush tea extracts in UVB-irradiated keratinocytes
Published 2025-06-01“…Microarray was used to investigate the expression of 84 oxidative stress response genes in response to rooibos and honeybush tea extracts and the effect of pre-exposure to extracts prior to UVB exposure was assessed. …”
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A Comparative Analysis of the Roles of von Willebrand Factor and ADAMTS13 in Hepatocellular Carcinoma: A Bioinformatics and Microarray-Based Study
Published 2025-04-01“…In this study, we aimed to investigate the effects of von Willebrand factor (VWF) and <i>ADAMTS13</i> on HCC prognosis, using bioinformatics tools. …”
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Mechanism and relevance of necroptosis to immune microenvironment of periodontitis: A pilot study
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Genome Array on Differentially Expressed Genes of Skin Tissue in Cashmere Goat at Early Anagen of Cashmere Growth Cycle Using DNA Microarray
Published 2014-10-01“…Approximately 10 200 probe sets were detected in skin tissue of 2-yr-old cashmere goat. …”
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Interdigitated Microarray Electrodes Based on Boron-doped Amorphous Carbon for Highly Sensitive Electroanalysis of Redox Analytes Having a Higher Standard Potential
Published 2025-02-01“…Interdigitated microarray electrodes were developed based on boron-doped amorphous carbon (B-a-C-IDA) that shows extremely higher overpotential for H2 and O2 evolution. …”
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