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581
Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome
Published 2016-01-01“…To assess the expression of autoantibodies in the blood plasma, we used a protein microarray, which allows for simultaneous determination of 9000 proteins per sample. …”
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582
Inhibition of SOD1 trimerization is a novel drug target for ALS disease
Published 2025-05-01“…To check the in vivo therapeutic effect of PRG-A-04, SOD1G93A−Tg mice were injected with PRG-A-04; then behavioral test, histological analysis and microarray were performed. …”
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583
Mechanisms of ag85a/b DNA vaccine conferred immunotherapy and recovery from Mycobacterium tuberculosis‐induced injury
Published 2023-05-01“…The gene expression profiles were analyzed using gene microarray technology to obtain differentially expressed (DE) genes. …”
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584
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma
Published 2025-08-01“…Inhibition or knockdown of USP7 reduces MGMT levels, as well as those of XPC, ALKBH2, and ALKBH3, impairs DNA repair capacity, and sensitizes GBM cells to TMZ, enabling effective treatment with reduced TMZ dosages. Clinically, tissue microarray analyses reveal that USP7 and MGMT co-overexpression in GBM correlates with poor patient survival. …”
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585
Human umbilical vein endothelial cell miRNA secretome highlights endothelial origin of serum miRNAs
Published 2025-07-01“…Our results also demonstrate that the microarray technology has great use in precision microRNA biomarker discovery using simple models, which should be utilised for further mapping of cell-type specific healthy signatures to further refine blood-based diagnostics.…”
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586
Identification and Characterization of Cyprinid Herpesvirus-3 (CyHV-3) Encoded MicroRNAs.
Published 2015-01-01“…MiRNAs from the two confirmed pre-miRNAs were also detected in gill tissue from CyHV-3-infected carp. …”
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587
R-locus for roaned coat is associated with a tandem duplication in an intronic region of USH2A in dogs and also contributes to Dalmatian spotting.
Published 2021-01-01“…We identified a putative causal variant in this region, an 11-kb tandem duplication (11,131,835-11,143,237) characterized by sequence read coverage and discordant reads of whole-genome sequence data, microarray probe intensity data, and a duplication-specific PCR assay. …”
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588
The impact of MITF expression on tumor-infiltrating lymphocytes in melanoma: Insights into immune microenvironment dynamics
Published 2025-02-01“…Archival formalin-fixed, paraffin-embedded tissue samples from 81 primary melanoma patients were analyzed via tissue microarray immunohistochemistry to assess MITF protein levels. …”
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589
Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules.
Published 2014-01-01“…We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based) and humans (mRNA-sequencing-based) and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. …”
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590
Cuproptosis-related signature and immune infiltration in age-related macular degeneration
Published 2025-09-01“…METHODS: The expression profiles of cuproptosis-related genes and immune signature in AMD based on the microarray dataset GSE29801 were analyzed. A total of 142 AMD samples were used to identify the cuproptosis-related differentially expressed genes (Cu-DEGs), together with the immune cell infiltration. …”
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591
Chlamydiaceae in wild, feral and domestic pigeons in Switzerland and insight into population dynamics by Chlamydia psittaci multilocus sequence typing.
Published 2019-01-01“…The highest infection rates were detected in feral (64/323) and domestic pigeons (5/34). …”
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592
The Novel Action of miR-193b-3p/CDK1 Signaling in HCC Proliferation and Migration: A Study Based on Bioinformatic Analysis and Experimental Investigation
Published 2022-01-01“…A growing number of novel targets underlying HCC pathophysiology have been detected using microarray high throughput screening platforms. …”
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593
Thyroid hormone signalling genes are regulated by photoperiod in the hypothalamus of F344 rats.
Published 2011-01-01“…Surprisingly, large changes in hypothalamic thyroid hormone levels or TRH expression were not detected. Expression of NPY and GALP, two genes known to regulate GHRH, were also changed by photoperiod. …”
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594
The Construction of ceRNA Regulatory Network Unraveled Prognostic Biomarkers and Repositioned Drug Candidates for the Management of Pancreatic Ductal Adenocarcinoma
Published 2025-06-01“…The mRNA, miRNA, and circRNA expression profiles of PDAC were obtained from nine microarray datasets. Differentially expressed genes (DEGs), microRNAs (DEmiRNAs), and circular RNAs (DEcircRNAs) were identified. …”
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595
Screening of key genes related to angiogenesis in rosacea based on bioinformatics analysis
Published 2025-04-01“…Methods The gene microarray dataset GSE65914 was retrieved from the Gene Expression Omnibus (GEO) repository. …”
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596
Quantitative Expression of SFN, lncRNA CCDC18-AS1, and lncRNA LINC01343 in Human Breast Cancer as the Regulator Biomarkers in a Novel ceRNA Network: Based on Bioinformatics and Exp...
Published 2022-01-01“…In this study, after performing GSEA and microarray analysis on the GSE71053 dataset, a new ceRNA network of CCDC18-AS1, LINC01343, hsa-miR4462, and SFN in BC was detected by bioinformatics analysis. …”
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597
Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke
Published 2025-04-01“…Three machine learning algorithms were employed to detect biomarkers from the core shared genes, and the diagnostic value of the hub genes was evaluated by establishing a predictive nomogram. …”
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598
An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas.
Published 2014-03-01“…We selected mostly surface-derived proteins, produced them using an in vitro rapid translation system and then printed them to generate the first protein microarray for a multi-cellular pathogen. Using well-established Brazilian cohorts of putatively resistant (PR) and chronically infected (CI) individuals stratified by the intensity of their S. mansoni infection, we probed arrays for IgG subclass and IgE responses to these antigens to detect antibody signatures that were reflective of protective vs. non-protective immune responses. …”
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599
Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.
Published 2013-01-01“…Here we present an approach how exome sequencing in combination with SNP microarray data may identify targets of chromosomal aberrations in myeloid malignancies. …”
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600
Cyr61 Mediates Angiotensin II-Induced Podocyte Apoptosis via the Upregulation of TXNIP
Published 2023-01-01“…Gene microarray was used to analyze the expression of mRNAs after treatment with Ang II. …”
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