Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation. by Lisa Y Pang, Emma L Gatenby, Ayako Kamida, Bruce A Whitelaw, Ted R Hupp, David J Argyle

“…We found that COX-2 inhibition had no effect on CSC growth, or resistance to chemotherapy. …”
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Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant. by Rhea N Coler, Sylvie Bertholet, Magdalini Moutaftsi, Jeff A Guderian, Hillarie Plessner Windish, Susan L Baldwin, Elsa M Laughlin, Malcolm S Duthie, Christopher B Fox, Darrick Carter, Martin Friede, Thomas S Vedvick, Steven G Reed

“…We report here on the characterization of a synthetic hexaacylated lipid A derivative, denoted as glucopyranosyl lipid adjuvant (GLA). We assessed the effects of GLA on murine and human dendritic cells (DC) by combining microarray, mRNA and protein multiplex assays and flow cytometry analyses. …”
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A plant diterpene counteracts juvenile hormone-mediated gene regulation during Drosophila melanogaster larval development. by Sang Woon Shin, Jun Hyoung Jeon, Seon Ah Jeong, Ji-Ae Kim, Doo-Sang Park, Yunhee Shin, Hyun-Woo Oh

“…Gene ontology analysis also suggested that some of the genes activated-by-JHA/repressed-by-JHD play roles in spermatogenesis. Affymetrix microarray-based analysis indicated that the expression of genes activated-by-JHA/repressed-by-JHD was testis-specific. …”
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Diagnosis of Coronary Heart Diseases Using Gene Expression Profiling; Stable Coronary Artery Disease, Cardiac Ischemia with and without Myocardial Necrosis. by Nabila Kazmi, Tom R Gaunt

“…Interestingly it also showed efficacy in discriminating myocardial infarction patients from patients with clinical symptoms of cardiac ischemia but no myocardial necrosis or stable coronary artery disease, despite the influence of batch effects and different microarray gene chips and platforms.…”
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Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks by James N. Warnock, Bindu Nanduri, Carol A. Pregonero Gamez, Juliet Tang, Daniel Koback, William M. Muir, Shane C. Burgess

“…Linear, two-cycle amplification of total RNA, followed by microarray was performed for transcriptome analysis (with qRT-PCR validation). …”
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Cytogenomic characterization of mosaic X-ring chromosomes in seventeen patients with Turner syndrome (TS)-42 years of experience at a single-site institution by Anita Madison, Carolyn Applegate, Victoria Stinnett, Diego Marrero Miranda, Chantal Cross, Kamaria Cayton Vaught, Ying S. Zou, Jaclyn B. Murry

“…Current guidelines recommend karyotype as the first-line test rather than SNP microarray analysis when aneuploidy is suspected. Conventional cytogenetics is still necessary to understand structural abnormalities, provide genomic context, and detect low-level mosaicism. …”
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Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology by Brian Cox, Max Kotlyar, Andreas I Evangelou, Vladimir Ignatchenko, Alex Ignatchenko, Kathie Whiteley, Igor Jurisica, S Lee Adamson, Janet Rossant, Thomas Kislinger

“…We collected protein and mRNA expression data through shot‐gun proteomics and microarray expression analysis of the highly vascular exchange region, microdissected from the human and mouse near‐term placenta. …”
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A very rare case of a newborn with tetrasomy 9p and literature review by Merve Süleyman, Sümeyra Oğuz, Gözdem Kaykı, Hasan Tolga Çelik, Pelin Özlem Şimsek-Kiper, Gülen Eda Utine, Şule Yiğit

“…Microarray analysis revealed 38,584 kb tetrasomic region at 9p24.3p13.1. …”
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Informative value of rapid microbiological diagnostic tests and experience in studying a procalcitonin assay in the evaluation of the activity of a mycobacterial population in chil... by L. V. Panova, E. S. Ovsyankina, M. M. Averbakh, F. A. Poluektova, O. A. Piskunova

“…Drug resistance in MBT was determined by a microarray test in only 16 (23.5%) out of 68 patients for lack or paucity of DNA in the diagnostic material. …”
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Association between a specific monocyte subset and heart failure with preserved ejection fraction in patients with uremia by Xinrui Wang, Minghui Song, Lu Ma, Yang Yang

“…Conclusions: Specific gene detections can be an important early warning indicator and guide physicians in evaluating the risk of HFpEF in ESRD.…”
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TLR3 Plays Significant Roles against HBV-Associated HCC by Xiao-lan Chen, Yu-yin Xu, Li Chen, Gui-lan Wang, Yin Shen

“…The apoptosis of tumor cells was also detected by TUNEL stain. Correlations between TLR3 expression and HBV infection, interstitial immunoreactive cells, and cells apoptosis in HCC were investigated. …”
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A long non-coding RNA lncRNA-PE promotes invasion and epithelial–mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway by Yuan Shen, Shanshan Liu, Hanyu Yuan, Xiaomin Ying, Hanjiang Fu, Xiaofei Zheng

“…However, the detailed mechanisms underlying their activities are not fully understood. Using microarray technology, a number of long non-coding RNAs were previously identified to be aberrantly expressed in hepatocellular carcinoma. …”
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iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models. by Bahadir Ozdemir, Wael Abd-Almageed, Stephanie Roessler, Xin Wei Wang

“…We defined a method to transform microarray data into graph representation that encodes miRNA and gene expression levels and the interactions between them as well. …”
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Immortalized Human Schwann Cell Lines Derived From Tumors of Schwannomatosis Patients. by Kimberly Laskie Ostrow, Katelyn Donaldson, Jaishri Blakeley, Allan Belzberg, Ahmet Hoke

“…Cell morphology was retained following multiple passaging and freeze/ thaw cycles. Gene expression microarray analysis was used to compare the cell lines with their respective parent tumors. …”
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Ubiquitin Specific Protease 26 (USP26) expression analysis in human testicular and extragonadal tissues indicates diverse action of USP26 in cell differentiation and tumorigenesis. by Matthew S Wosnitzer, Anna Mielnik, Ali Dabaja, Brian Robinson, Peter N Schlegel, Darius A Paduch

“…Immunofluorescence colocalization studies were performed with formalin-fixed/paraffin-embedded and frozen tissues using primary and secondary antibodies to detect USP26 and AR protein expression. Human microarray dot blots were used to identify protein expression in extra-gonadal tissues. …”
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Molecular diagnosis of Usher syndrome: application of two different next generation sequencing-based procedures. by Danilo Licastro, Margherita Mutarelli, Ivana Peluso, Kornelia Neveling, Nienke Wieskamp, Rossella Rispoli, Diego Vozzi, Emmanouil Athanasakis, Angela D'Eustacchio, Mariateresa Pizzo, Francesca D'Amico, Carmela Ziviello, Francesca Simonelli, Antonella Fabretto, Hans Scheffer, Paolo Gasparini, Sandro Banfi, Vincenzo Nigro

“…We analyzed a total of 12 patients, most of which were negative for previously described mutations in known USH genes upon primer extension-based microarray genotyping. We enriched the NGS template either by whole exome capture or by Long-PCR of the known USH genes. …”
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Neutrophil Extracellular Traps Drive Kidney Stone Formation by Zhiming Yang, Xiong Chen, Guannan Qi, Jie Gu, Zheng Liu, Xiaobo Zhang

“… Introduction: This study aims to explore the contribution of neutrophil extracellular traps (NETs) to kidney stones. Methods: The microarray data from GSE73680 and bioinformatic analysis were applied to identify differentially expressed genes in patients with kidney stones. …”
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Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant ho... by Laura Miozzi, Chiara Napoli, Luca Sardo, Gian Paolo Accotto

“…Here we present the first microarray study of transcriptional changes induced by the phloem-limited geminivirus TYLCSV infecting tomato, its natural host. …”
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Alternative splicing of NURF301 generates distinct NURF chromatin remodeling complexes with altered modified histone binding specificities. by So Yeon Kwon, Hua Xiao, Carl Wu, Paul Badenhorst

“…By comparing microarray expression profiles and phenotypes of null Nurf301 mutants with mutants that remove the C-terminal PHD fingers and bromodomain, we show that full-length NURF301 is not essential for correct expression of the majority of NURF gene targets in larvae. …”
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Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with porcine circovirus 2b. by Bettina Mavrommatis, Victoria Offord, Robert Patterson, Mick Watson, Theo Kanellos, Falko Steinbach, Sylvia Grierson, Dirk Werling

“…Furthermore, PCV2 has been detected in bone-marrow samples, potentially enabling an easy spread and reservoir for the virus. …”
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