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401
Amogel: a multi-omics classification framework using associative graph neural networks with prior knowledge for biomarker identification
Published 2025-03-01“…Abstract The advent of high-throughput sequencing technologies, such as DNA microarray and DNA sequencing, has enabled effective analysis of cancer subtypes and targeted treatment. …”
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402
Global gene expression profiling reveals SPINK1 as a potential hepatocellular carcinoma marker.
Published 2013-01-01“…Six genes identified by microarray as highly expressed in HH-HCC were confirmed by RT qPCR. …”
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403
FGFR3-TACC3 fusion gene promotes glioblastoma malignant progression through the activation of STAT3 signaling pathway
Published 2025-04-01“…A series of phenotypic experiments, including CCK-8, EdU, colony-formation assay, wound healing assay, and transwell assay were conducted to detect the effects of F3-T3 on proliferation, invasion, and migration of glioma cells. …”
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404
TRIM22 promotes glioblastoma development by ubiquitinating Bcl-2
Published 2025-12-01“…A TRIM22-overexpressing ubiquitination microarray identified TRIM22 as a potential activator of Bcl-2. …”
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405
Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer
Published 2022-11-01“…Material and methods. a total of 130 breast cancer patients were included in the study. microarray analysis was performed on Affymetrix Cytoscantm HD Array high-density DNA chips to assess LOH status. …”
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406
Enhanced leukemia prediction using hybrid ant colony and ant lion optimization for gene selection and classification
Published 2025-06-01“…The proposed model, which identifies the optimal feature set for classification using Support Vector Machine (SVM), has achieved an impressive prediction accuracy of 93.94 %. Results on microarray datasets for leukemia prediction show that the hybrid approach outperforms other methods in terms of both effectiveness and efficiency. …”
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407
FAM111B knockdown attenuates tumorigenesis of ovarian cancer via the downregulation of MYC
Published 2025-08-01“…Immunohistochemical analyses conducted on tissue-microarray samples obtained from patients with serous ovarian cancer indicated that elevated levels of FAM111B expression were associated with unfavorable prognostic outcomes. …”
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408
Bioinformatics and network pharmacology-based study to elucidate the multi-target pharmacological mechanism of the indigenous plants of Medina valley in treating HCV-related hepato...
Published 2023-06-01“…Following that, this study combines network pharmacology with bioinformatics approaches to potentially revolutionize HCV-related HCC treatment by identifying effective phytochemicals of indigenous plants of Medina valley. …”
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409
Global challenges and solutions to achieving and sustaining measles and rubella elimination
Published 2024-12-01“…Progress will be supported through technological innovations such as microarray patch vaccines. Whether this holistic approach will be more effective than vertical initiatives at achieving measles and rubella elimination remains to be seen. …”
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410
Investigation on the Electron Emission Regularity of Sputtered Boron Nitride Thin Films and Microstructured Array Surfaces
Published 2025-03-01“…The results of laser etching on the BN bulk surface to form microarray structures show that the EEC of BN bulk decreases significantly with the increase of the average aspect ratio of the microstructures. …”
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411
Poly-β-D-(1,6)-N-acetyl-glucosamine (PNAG) glycan vaccines with broad spectrum neutralizing activities
Published 2025-07-01“…Glycan microarray analysis shows that dPNAG glycans with DP8 and DP12 are optimal, with corresponding protein conjugates eliciting the highest IgG titers. …”
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412
Genetic testing for oral clefts: reflections based on a single Brazilian public genetics service
Published 2025-08-01“…They also show the need to improve public health policies for genetic evaluation, diagnostic tests, and genetic counseling for an effective NPCCPRD.…”
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413
Identification of Novel Molecular Panel as Potential Biomarkers of PAN-Gastrointestinal Cancer Screening: Bioinformatics and Experimental Analysis
Published 2025-07-01“…In the present study, using integrated transcriptomics, RNA-Seq and microarray data, from the TCGA and GEO databases, respectively, were combined to discover and validate a global biomarker panel for PAN-gastrointestinal cancers. …”
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414
Metformin inhibits high glucose‐induced apoptosis of renal podocyte through regulating miR‐34a/SIRT1 axis
Published 2024-01-01“…A conditionally immortalized human podocyte cell line was cultivated in d‐glucose (30 mM). Results Microarray and RT‐qPCR revealed that miR‐34a was downregulated in HG‐treated podocytes. …”
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415
Prenatal Diagnosis of Fetal Visceral Situs Abnormalities: A Retrospective Study
Published 2025-07-01“…Moreover, for fetuses diagnosed with visceral situs abnormalities and pregnant women with normal chromosomal results, WES remains essential to improve the detection rates of PCD or other genetic abnormalities.…”
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416
Potential role of SLC6A3 in neurodevelopmental impairments associated with corpus callosum abnormalities: insights from CNV analysis and clinical phenotyping
Published 2025-08-01“…Methods From January 2021 to July 2023, 13 children with MRI-confirmed CCAs underwent chromosomal microarray analysis (CMA) for CNV detection. We performed bioinformatic analyses (Gene Ontology, STRING network) to identify neurodevelopmental genes within pathogenic CNVs, and clinical follow up assessed neurobehavioral outcomes. …”
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417
Identification of PECAM1 as a Prognostic Biomarker for Lung Adenocarcinoma
Published 2025-04-01“…<b>Methods</b>: We examined three microarray datasets from the Gene Expression Omnibus (GSE10072, GSE33356, and GSE18842) to detect DEGs between tumor and normal lung tissues. …”
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418
Study on hsa_circ_101209 in Plasma of Pregnant Women with Deep Venous Thrombosis
Published 2025-01-01“…Yuhong Zhang, Jun Li Center for Obstetrics and Reproductive Medicine, The Affiliated Hospital of Yunnan University, Kunming City, Yunnan Province, 650032, People’s Republic of ChinaCorrespondence: Jun Li, Center for Obstetrics and Reproductive Medicine, The Affiliated Hospital of Yunnan University, No. 176, Qingnian Road, Kunming, Yunnan, 650032, People’s Republic of China, Email lijun1152061295@hotmail.comBackground: This study analyzed the expression and diagnostic value of hsa_circ_101209 in plasma of pregnant women with in deep vein thrombosis (DVT).Methods: By circRNA microarray detection and GO/KEGG analysis, hsa_circ_14797 targeting miRNA-mRNA network was predicted. …”
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419
Long-read genome sequencing resolves complex genomic rearrangements in rare genetic syndromes
Published 2024-12-01“…Abstract Long-read sequencing can often overcome the deficiencies in routine microarray or short-read technologies in detecting complex genomic rearrangements. …”
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420
VEGF Contributes to Mesenchymal Stem Cell-Mediated Reversion of Nor1-Dependent Hypertrophy in iPS Cell-Derived Cardiomyocytes
Published 2021-01-01“…Phenylephrine (PE) was used to induce hypertrophy in murine iPS-CM, and markers of hypertrophy were identified by microarray analysis. Murine MSCs were treated with IFN-γ and IL-1β to enhance their paracrine activity, and transcriptional profiling was performed by microarray analysis. …”
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