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301
Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression
Published 2025-05-01“…Methods TNBC-related datasets were retrieved from The Cancer Genome Atlas and selected by Prediction Analysis of Microarray 50 analysis to assess the expression of PMAIP1 in the samples. …”
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302
Deep learning-based spatial analysis on tumor and immune cells of pathology images predicts MIBC prognosis.
Published 2025-01-01“…Lymph_inside % can be an effective biomarker for predicting MIBC prognosis. …”
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303
Pan-cancer analysis identifies CD155 as a promising target for CAR-T cell therapy
Published 2025-06-01“…Methods The expression of CD155 was analyzed across various cancer types using data from The Cancer Genome Atlas (TCGA) and validated by tissue microarray analysis. The impact of CD155 on T cell mediated cytotoxicity was analyzed using CD155 over-expression or knockout tumor cells. …”
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304
On-Chip DNA Assembly via Dielectrophoresis
Published 2025-01-01“…While there exist several microarray-based oligo synthesis technologies, on-chip gene assembly has yet to be demonstrated. …”
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305
A Novel Feature Selection Method for Classification of Medical Data Using Filters, Wrappers, and Embedded Approaches
Published 2022-01-01“…Feature selection is the process of identifying the most relevant features from the given data having a large feature space. Microarray datasets are comprised of high-quality features and very few samples of data. …”
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306
A first large study of whole-exome sequencing (WES) in 489 patients with suspected rare genetic disorders at a tertiary centre in Malaysia
Published 2025-01-01“…Whole exome sequencing (WES) is a comprehensive test that can detect not only many of the same large deletions and duplications as CMA, but also detect other genetic variants that are detected by gene panels. …”
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307
Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
Published 2019-03-01“…Methods We downloaded the microarray data from the Gene Expression Omnibus (GEO) database. …”
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308
A retrospective analysis of prenatal genetic results in fetal hydronephrosis.
Published 2025-01-01“…<h4>Objective</h4>To discuss the application value of technologies such as chromosome microarray analysis (CMA) in fetuses with hydronephrosis and pyelectasis.…”
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309
Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma
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310
Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
Published 2018-01-01“…Methods. lncRNA and mRNA profiling of PBMCs from 17 smokers and 14 COPD subjects was detected by high-throughput microarray. The expression of dysregulated lncRNAs was validated by qPCR. …”
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311
MicroRNA let-7f protects against H2O2-induced oxidative damage in neuroblastoma cells by targeting AKT-2
Published 2020-04-01“…Material and methods miRNA microarray analysis was performed to detect the miRNAs’ differential expression in AD patients and normal elderly volunteers. …”
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312
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis
Published 2025-02-01“…CCK-8, colony formation, EdU staining, wound-healing, Transwell, western blotting and RT-qPCR were used to detect the effects of CLIP4 on the proliferation, migration and epithelial-mesenchymal transition (EMT) of HCC cells. …”
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313
Machine learning-based single-sample molecular classifier for cancer grading
Published 2025-07-01“…Next, we showed that mGrades were effective in assessing risk levels for G2 samples. …”
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314
Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation
Published 2025-05-01“…The levels of anti-CRP and SLE-associated antibodies were assessed, and a microarray-based linear epitope mapping was performed to detect binding sites on the full CRP monomer. …”
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315
Gene Expression Profiles for Predicting Metastasis in Breast Cancer: A Cross-Study Comparison of Classification Methods
Published 2012-01-01“…This study compares the performance of seven classification methods and the effect of voting for predicting metastasis outcome in breast cancer patients, in three situations: within the same dataset or across datasets on similar or dissimilar microarray platforms. …”
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316
Identification of CD36 as a contributor in inflammatory response of rheumatoid arthritis and screening of feasible bioactive drugs targeting it
Published 2025-06-01“…Receiver operating characteristic (ROC) curve was used to evaluate the diagnostic effect of the predicted hub genes. In addition, drug prediction was performed through virtual screening. mRNA and protein expression of cluster of differentiation 36 (CD36) were detected by RT-qPCR and Western blot. …”
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317
Identification of sero-reactive antigens for the early diagnosis of Johne's disease in cattle.
Published 2017-01-01“…JD has a high herd prevalence and causes serious animal health problems and significant economic loss in domesticated ruminants throughout the world. Since serological detection of MAP infected animals during the early stages of infection remains challenging due to the low sensitivity of extant assays, we screened 180 well-characterized serum samples using a whole proteome microarray from Mycobacterium tuberculosis (MTB), a close relative of MAP. …”
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318
ARHGAP42 promotes cell migration and invasion involving PI3K/Akt signaling pathway in nasopharyngeal carcinoma
Published 2018-08-01“…Microarray and real‐time quantitative PCR were used for a mRNA profiling of ARHGAP42 in nasopharyngeal primary and metastatic carcinoma tissues. …”
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319
The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella.
Published 2011-10-01“…The microarray analyses also reveal a lack of recognition of glycan sequences terminating in the N-glycolyl form of sialic acid by EtMIC3. …”
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320
Mutation Spectrum of the ABCA4 Gene in a Greek Cohort with Stargardt Disease: Identification of Novel Mutations and Evidence of Three Prevalent Mutated Alleles
Published 2018-01-01“…Direct sequencing improved significantly the complete characterization rate, that is, identification of two mutations compared to the microarray analysis (93.1% versus 50%). In total, 40 distinct potentially disease-causing variants of the ABCA4 gene were detected, including six previously unreported potentially pathogenic variants. …”
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