ZNF37A downregulation promotes TNFRSF6B expression and leads to therapeutic resistance to concurrent chemoradiotherapy in rectal cancer patients by Ying Huang, Jing Jin, Ningxin Ren, Hongxia Chen, Yan Qiao, Shuangmei Zou, Xin Wang, Linlin Zheng, Ye-Xiong Li, Wen Tan, Dongxin Lin

“…The identification a signature comprising a group of genes as markers of cancer response to chemoradiotherapy would be more appropriate and effective for predicting chemoradiotherapy efficacy. …”
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Mechanisms of ag85a/b DNA vaccine conferred immunotherapy and recovery from Mycobacterium tuberculosis‐induced injury by Nan Wang, Yan Liang, Qianqian Ma, Jie Mi, Yong Xue, Yourong Yang, Lan Wang, Xueqiong Wu

“…The gene expression profiles were analyzed using gene microarray technology to obtain differentially expressed (DE) genes. …”
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USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma by Jiabing Li, Xiaorong Feng, Zhaohui Liu, Yunfang Deng, Zhiming Sun, Bei Chen, Lihui Wu, Xiaolong Wang, Lin Miao, Liyuan Zeng, Lei Hu, Yuming He, Ying Sheng, Yue Liu, Yu Zhao

“…Inhibition or knockdown of USP7 reduces MGMT levels, as well as those of XPC, ALKBH2, and ALKBH3, impairs DNA repair capacity, and sensitizes GBM cells to TMZ, enabling effective treatment with reduced TMZ dosages. Clinically, tissue microarray analyses reveal that USP7 and MGMT co-overexpression in GBM correlates with poor patient survival. …”
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Characterization of Human Knee and Chin Adipose-Derived Stromal Cells by Magali Kouidhi, Phi Villageois, Carine M. Mounier, Corinne Ménigot, Yves Rival, David Piwnica, Jérôme Aubert, Bérengère Chignon-Sicard, Christian Dani

“…Paired chin and knee fat depots were harvested from 11 subjects and gene expression profiles were determined by DNA microarray analyses. Adipose-derived stromal cells (ASCs) from both sites were isolated and analyzed for their capacity to proliferate, form clones, and differentiate. …”
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Genome-wide and rna-seq highlight genetic characteristics of rumpless signals in piao chicken by Wang Mei QI, Xing Fu ZHANG, Li Wen SONG, Zai Xia LIU, Yuan CHAI, Yan Yong SUN

“…Understanding the genetic relationship between rumpless chicken and other specific selection target breeds in the process of differentiation of the rumpless signal genes is helpful to reveal the genetic basis of rumplessnesss. …”
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Interaction of Wnt Signaling with BMP/Smad Signaling during the Transition from Cell Proliferation to Myogenic Differentiation in Mouse Myoblast-Derived Cells by Kumiko Terada, Satomi Misao, Naoki Katase, Shin-ichiro Nishimatsu, Tsutomu Nohno

“…The BMP antagonist noggin effectively stimulated muscle differentiation through binding to endogenous BMPs, and the effect of noggin was enhanced by the presence of Wnt3a and Wnt4. …”
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Integrating single-cell RNA sequencing, WGCNA, and machine learning to identify key biomarkers in hepatocellular carcinoma by Gang Wang, Jiaxing Zhang, Yirong Li, Yuyu Zhang, Weiwei Dong, Hengquan Wu, Jinglan Wang, Peiqing Liao, Ziqiang Yuan, Tao Liu, Wenting He

“…Abstract The microarray and single-cell RNA-sequencing (scRNA-seq) datasets of hepatocellular carcinoma (HCC) were downloaded from the Gene Expression Omnibus (GEO) database. …”
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Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway. by Qian Chen, Sanjay Swaminathan, De Yang, Lue Dai, Hongyan Sui, Jun Yang, Ronald L Hornung, Yanmei Wang, Da Wei Huang, Xiaojun Hu, Richard A Lempicki, Tomozumi Imamichi

“…Of note, other IL-12 family members (IL-12, IL-23 and IL-35) had no effect on HIV-1 replication. Microarray studies of IL-27 treated DCs showed no up-regulation of Type I (IFN) gene expression. …”
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An Immune-Related Prognostic Classifier Is Associated with Diffuse Large B Cell Lymphoma Microenvironment by Xiao-Jie Liang, Rui-ying Fu, He-nan Wang, Jing Yang, Na Yao, Xin-di Liu, Liang Wang

“…Results. Eighteen IRGs were selected to construct the classifier. The multi-IRG classifier showed powerful predictive ability. …”
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MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis by Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro Okamoto

“…Abstract The detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA) profiles of serum from pediatric patients (0–6 years of age) with G-PAVMs and after the Fontan procedure without G-PAVMs. …”
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Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer. by Alexander Henke, O Cathal Grace, George R Ashley, Grant D Stewart, Antony C P Riddick, Henry Yeun, Marie O'Donnell, Richard A Anderson, Axel A Thomson

“…Four candidates (Decorin, SPARC, Spry-1, Tsukushi) were immunolocalised in human foetal prostate (weeks 14, 16, 19) and expression of Decorin was evaluated on a human prostate cancer tissue microarray. In embryonic and perinatal rats Decorin, Semaphorin6D, SPARC, Spry-1 and Tsukushi were expressed with varying distribution patterns throughout the mesenchyme at E17.5, E19.5, P0.5 and P6.5. …”
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Integrative Bioinformatics Analysis Unravel the Association between Intracerebral Hemorrhage and Cellular Apoptosis through Immune Infiltration by Pandi Chen, Gengfan Ye, Jia Li, Kuan Feng, Guangyao Zhu, Maosong Chen, Wei Chen

“…Key genes were identified through least absolute shrinkage and selection operator regression after model validation. …”
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Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/N... by Sajid Javed, Leanne Marsay, Alice Wareham, Kuiama S Lewandowski, Ann Williams, Michael J Dennis, Sally Sharpe, Richard Vipond, Nigel Silman, Graham Ball, Karen E Kempsell

“…Further data refinements identified groups of key markers showing group-specific expression patterns, with a substantial reprogramming event evident at the four to six week interval. Selected statistically-significant gene entities from this study and other immune and apoptotic markers were validated using qPCR, which confirmed many of the results obtained using microarray hybridisation. …”
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Identification of potential biomarkers for 2022 Mpox virus infection: a transcriptomic network analysis and machine learning approach by Joy Prokash Debnath, Kabir Hossen, Sabrina Bintay Sayed, Md. Sayeam Khandaker, Preonath Chondrow Dev, Saifuddin Sarker, Tanvir Hossain

“…This study aimed to identify the differentially expressed genes (DEGs) induced by the 2022 MPXV infection through comprehensive bioinformatics analyses of microarray and RNA-Seq datasets from post-infected cell types with different MPXV clades. …”
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RTP4, a Biomarker Associated with Diagnosing Pulmonary Tuberculosis and Pan-Cancer Analysis by Hao Li, Qin Zhou, ZhiXiang Ding, QingHai Wang

“…Pulmonary tuberculosis (PTB) is a global epidemic of infectious disease; the purpose of our study was to explore new potential biomarkers for the diagnosis of pulmonary tuberculosis and to use the biomarkers for further pan-cancer analysis. Methods. Four microarray gene expression sets were downloaded from the GEO public databases and conducted for further analysis. …”
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Citrus flavonoids for overcoming breast cancer resistance to methotrexate: identification of potential targets of nobiletin and sinensetin by Adam Hermawan, Naufa Hanif, Dyaningtyas Dewi Pamungkas Putri, Nurul Fatimah, Heri Himawan Prasetio

“…Protein targets of citrus flavonoids were identified from multiple databases and were collected using Venny 2.1. Microarray data of MCF-7 and MCF-7/MTX cells were acquired from the Gene Expression Omnibus. …”
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Anti-Obesity Properties of <i>Boesenbergia rotunda</i> Rhizome Extract: Regulation of Inflammation, Lipid Metabolism, and Insulin Signaling in <i>ob/ob</i> Mice by Muhammad Hermawan Widyananda, Dinia Rizqi Dwijayanti, Airi Fujii, Keita Minamisaka, Yuto Nishidono, Mikio Nishizawa, Nashi Widodo

“…Next, we investigated the anti-obesity effects of BR extract in <i>ob/ob</i> mice, a type 2 diabetes mellitus model. …”
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γ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway. by Corina Wilding, Katharina Bell, Sabine Beck, Sebastian Funke, Norbert Pfeiffer, Franz H Grus

“…We found a protective effect of γ-synuclein antibody resulting in an increased viability (up to 15%) and decreased reactive oxygen species levels (up to -12%) of glutamate and oxidative stressed RGC-5. …”
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16S Ribosomal Ribonucleic Acid Gene Polymerase Chain Reaction in the Diagnosis of Bloodstream Infections: A Systematic Review and Meta-Analysis. by Guoming Su, Zhuqing Fu, Liren Hu, Yueying Wang, Zuguo Zhao, Weiqing Yang

“…Further prospective studies are needed to assess the diagnostic value of PCR amplification and DNA microarray hybridization of 16S rRNA gene in the future.…”
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Differential roles of ERα and ERβ in normal and neoplastic development in the mouse mammary gland. by Rajendra G Mehta, Michael Hawthorne, Rajeshwari R Mehta, Karen E O Torres, Xinjian Peng, David L McCormick, Levy Kopelovich

“…The data demonstrate distinct roles for ERα and ERβ in normal and neoplastic development in the mouse mammary gland, and suggest that EGF can mimic the ERα-mediated effects of E in this organ.…”
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