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241
Penaeus vannamei Genetic Evaluation for Growth and Survival Traits During White Spot Syndrome Virus Infection Based on 55K SNP Chip
Published 2025-06-01“…The genetic correlation between the survival time of individuals against WSSV and SS50 was 0.95±0.03, which was not significantly different from 1 (P > 0.05).The study showed that the genetic assessment of the growth of P. vannamei by microarray can effectively improve the accuracy of the assessment, the evaluation of WSSV survival time traits may be affected by the selection of individuals and other factors, and the prediction accuracy was not significantly improved. …”
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242
Evaluation of gene expression classification studies: factors associated with classification performance.
Published 2014-01-01“…The MAQC II study on cancer classification problems has found that performance was affected by factors such as the classification algorithm, cross validation method, number of genes, and gene selection method. In this paper, we study the hypothesis that the disease under study significantly determines which method is optimal, and that additionally sample size, class imbalance, type of medical question (diagnostic, prognostic or treatment response), and microarray platform are potentially influential. …”
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243
Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
Published 2018-01-01“…Methods. lncRNA and mRNA profiling of PBMCs from 17 smokers and 14 COPD subjects was detected by high-throughput microarray. The expression of dysregulated lncRNAs was validated by qPCR. …”
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244
Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation
Published 2025-05-01“…The levels of anti-CRP and SLE-associated antibodies were assessed, and a microarray-based linear epitope mapping was performed to detect binding sites on the full CRP monomer. …”
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245
Identification of Hub Biomarkers and Immune and Inflammation Pathways Contributing to Kawasaki Disease Progression with RT-qPCR Verification
Published 2023-01-01“…Patients and Methods. Gene microarray data were collected from the Gene Expression Omnibus database. …”
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246
HDAC1 Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer
Published 2025-03-01“…However, there are no studies on the immunological aspects of HDAC1 in non-small cell lung cancer (NSCLC).Methods: In this research, we used the Cancer Genome Atlas (TCGA) public database combined with tissue microarray (TMA) to investigate HDAC1 expression and prognosis in NSCLC. …”
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247
Bioinformatics meets machine learning: identifying circulating biomarkers for vitiligo across blood and tissues
Published 2025-05-01“…The merged microarray data were then used for WGCNA to identify modules of features genes. …”
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248
Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma
Published 2018-05-01Get full text
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249
Machine learning-based single-sample molecular classifier for cancer grading
Published 2025-07-01“…Next, we showed that mGrades were effective in assessing risk levels for G2 samples. …”
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250
Inhibition of SOD1 trimerization is a novel drug target for ALS disease
Published 2025-05-01“…To check the in vivo therapeutic effect of PRG-A-04, SOD1G93A−Tg mice were injected with PRG-A-04; then behavioral test, histological analysis and microarray were performed. …”
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251
Gene Expression Profiles for Predicting Metastasis in Breast Cancer: A Cross-Study Comparison of Classification Methods
Published 2012-01-01“…This study compares the performance of seven classification methods and the effect of voting for predicting metastasis outcome in breast cancer patients, in three situations: within the same dataset or across datasets on similar or dissimilar microarray platforms. …”
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252
Machine learning reveals CAT gene as a novel potential diagnostic and prognostic biomarker in non-small cell lung cancer
Published 2024-12-01“…Furthermore, immunohistochemical staining was performed in an independent cohort from a tissue microarray. Additionally, cell culture and RT-qPCR were employed for external validation. …”
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253
KRT6A, KRT6B, PKP1, and PKP3 as key hub genes in esophageal cancer: A combined bioinformatics and experimental study
Published 2025-09-01“…In this study, we downloaded the microarray datasets GSE157808 and GSE92396 from the Gene Expression Omnibus (GEO). …”
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254
Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells
Published 2025-05-01“…Methods The surgical specimens of six patients with GCY were included to construct a tissue microarray containing the tumor core region (TCR), cancer-adjacent tissue (CAT), and normal gastric tissue (NGT). …”
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255
The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella.
Published 2011-10-01“…The microarray analyses also reveal a lack of recognition of glycan sequences terminating in the N-glycolyl form of sialic acid by EtMIC3. …”
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256
Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array.
Published 2014-01-01“…These results led us to perform a case-control study using human protein microarrays to identify the antibody profiles of serum samples from 20 ALS patients and 20 healthy controls. …”
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257
Identification of Differentially Expressed Genes and Elucidation of Pathophysiological Relevance of ABCA1 in HaCaT Cells Induced by PM2.5
Published 2021-01-01“…Cell cycle distribution and apoptosis were detected by flow cytometry. Microarray analyses were used to find out the microarray gene expression profiling; data processing included gene enrichment and pathway analysis. …”
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258
Knockdown of A-kinase anchor protein 4 inhibits proliferation of triple-negative breast cancer cells and
Published 2020-04-01Get full text
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259
A systems biological approach reveals multiple crosstalk mechanism between gram-positive and negative bacterial infections: an insight into core mechanism and unique molecular sign...
Published 2014-01-01“…Further, to identify candidate molecules, the TLRs specific nodes were prioritized using microarray differential expressed genes. Of the top prioritized TLR 2 molecules, 70% were co-expressed. …”
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260
Cystatin B Promotes the Proliferation, Migration, and Invasion of Intrahepatic Cholangiocarcinoma
Published 2025-01-01“…The clinical significance of CSTB was analyzed through immunohistochemical staining of a tissue microarray. Subsequently, the biological effects of CSTB overexpression or knockdown on iCCA cells were evaluated in vitro and in vivo. …”
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