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481
Stroma regulates increased epithelial lateral cell adhesion in 3D culture: a role for actin/cadherin dynamics.
Published 2011-04-01“…The upregulated growth factors TGFβ2, CXCL12 and FGF10 were selected for further analysis because of previous associations with morphology. …”
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482
Cuproptosis-related signature and immune infiltration in age-related macular degeneration
Published 2025-09-01“…Next, SLC31A1 and VEGFA was selected as hub genes by performance evaluation in an external dataset GSE160011, further analysis showed that SLC31A1 and VEGFA were associated with pathways related to immune signaling and immune function, which were then observed in relation to infiltrating immune cells. …”
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483
Chlamydiaceae in wild, feral and domestic pigeons in Switzerland and insight into population dynamics by Chlamydia psittaci multilocus sequence typing.
Published 2019-01-01“…Additionally, multilocus sequence typing of twelve selected C. psittaci-positive samples revealed closely related sequence types (ST) between and within different Swiss cities. …”
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484
Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome.
Published 2011-01-01“…We also identified 1279 putative androgen-regulated alternative events, of which 325 (∼25%) mapped to known alternative splicing events or alternative first/last exons. We selected 30 androgen-dependent alternative events for RT-PCR validation, including mRNAs derived from genes encoding tumour suppressors and cell cycle regulators. …”
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485
Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis
Published 2024-10-01“…Methods Five DCM-related microarray datasets were downloaded from the Gene Expression Omnibus (GEO). …”
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486
An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas.
Published 2014-03-01“…Herein, we take advantage of recent advances in systems biology and longitudinal studies in schistosomiasis endemic areas in Brazil to pilot an immunomics approach to the discovery of schistosomiasis vaccine antigens. We selected mostly surface-derived proteins, produced them using an in vitro rapid translation system and then printed them to generate the first protein microarray for a multi-cellular pathogen. …”
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487
Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.
Published 2013-01-01“…Therefore, we studied chromosome 11 in a total of 813 samples from 773 individual patients with different myeloid malignancies by SNP microarrays and complemented the data with exome sequencing in selected cases exhibiting chromosome 11 defects. …”
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488
FANCI is involved in the malignant progression of glioma cells by regulating the Akt/Bcl-2 signaling pathway
Published 2025-05-01“…Methods The expression of FANCI in glioma cells was analyzed by bioinformatics and microarray. Lentivirus transfection was used to regulate the expression of FANCI in glioma cells. …”
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489
Transcriptomics, Proteomics and Bioinformatics in Atrial Fibrillation: A Descriptive Review
Published 2025-02-01“…Different devices for processing RNA and proteomic samples vary from RNA sequencing and microarray to a wide range of mass spectrometry techniques such as Orbitrap, Quadrupole, LC-MS, and hybrid systems. …”
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490
Cell cycle regulation and cytoskeletal remodelling are critical processes in the nutritional programming of embryonic development.
Published 2011-01-01“…While these describe processes leading from nutritional insult to development of the actual pathology, the initial underlying cause of the programming effect remains elusive. To establish the primary drivers of programming, this study aimed to capture embryonic gene and protein changes in the whole embryo at the time of nutritional insult rather than downstream phenotypic effects. …”
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491
Stability indicators in network reconstruction.
Published 2014-01-01“…Finally, we demonstrate a strong combined effect of different reconstruction methods and phenotype subgroups on a hepatocellular carcinoma miRNA microarray dataset (240 subjects), and we validate the analysis on a second dataset (166 subjects) with good reproducibility.…”
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492
Regulation of Myogenesis by MechanomiR-200c/FoxO3 Axis
Published 2025-06-01“…Overexpression of mechanomiR-200c revoked the effect of stretch on myoblast differentiation, and the introduction of the mechanomiR-200c antagomir restored the stretch effect. …”
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493
Osteopontin is induced by TGF-β2 and regulates metabolic cell activity in cultured human optic nerve head astrocytes.
Published 2014-01-01“…Activation was initially demonstrated by Oligo GEArray microarray and confirmed by semiquantitative (sq) RT-PCR, realtime RT-PCR and western blot. …”
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494
Exosome-like nanovesicles derived from kale juice enhance collagen production by downregulating Smad7 in human skin fibroblasts
Published 2025-02-01“…In this study, we investigated the effects of glucoraphanin-enriched kale (GEK)-derived ELNs (GELNs) on collagen production in normal human dermal fibroblasts NB1RGB. …”
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495
Molecular correlates of social dominance: a novel role for ependymin in aggression.
Published 2011-04-01“…We used a custom cDNA microarray to profile brain transcript expression in a model species, the rainbow trout, which forms tractable linear hierarchies. …”
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496
From the environment to the host: re-wiring of the transcriptome of Pseudomonas aeruginosa from 22°C to 37°C.
Published 2014-01-01“…Microarray analysis of PAO1 grown in Lysogeny broth at mid-exponential phase at 22°C and 37°C revealed that temperature changes are responsible for the differential transcriptional regulation of 6.4% of the genome. …”
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497
Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Bra...
Published 2016-01-01“…Changes in gene expression (microarray and qPCR) were assessed in the cingulate cortex. …”
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498
Improvement in Wrinkles by a Fairy Chemical, 2-Aza-8-oxohypoxanthine
Published 2025-06-01“…2-aza-8-oxohypoxanthine (AOH) has been shown to improve skin barrier function according to DNA microarray studies of normal human epidermal keratinocytes. …”
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499
Androgen Modulates Functions of Endothelial Progenitor Cells through Activated Egr1 Signaling
Published 2016-01-01“…Researches show that androgens have important effects on migration of endothelial cells and endothelial protection in coronary heart disease. …”
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500
Identification and analysis of neutrophil extracellular trap-related genes in periodontitis via bioinformatics and experimental verification
Published 2025-08-01“…Methods The microarray datasets were obtained from the Gene Expression Omnibus (GEO) database. …”
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