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321
Integrative analysis of co-expression networks and codon usage bias in maize under biotic stress.
Published 2025-01-01“…Understanding the complex networks underlying the biotic stress response in maize is crucial for developing effective approaches to improve tolerance. We identified 1449 differentially expressed genes (DEGs) by meta-analysis of the public microarray gene expression profile. …”
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322
c-Triadem: A constrained, explainable deep learning model to identify novel biomarkers in Alzheimer's disease.
Published 2025-01-01“…We trained the model with blood genotyping data, microarray, and clinical features from the Alzheimer's Neuroimaging Disease Initiative (ADNI). …”
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323
Molecular profiles of tumor contrast enhancement: A radiogenomic analysis in anaplastic gliomas
Published 2018-09-01“…Gene set enrichment analysis (GSEA), significant analysis of microarray, generalized linear models, and Least absolute shrinkage and selection operator algorithm were used to explore radiogenomic and prognostic signatures of AG patients. …”
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324
Identifying a unique chromosomal pattern to predict the gemcitabine response in patients with cholangiocarcinoma
Published 2025-04-01“…This signature pattern could provide the knowledge to improve a predictive biomarker for GEM response, benefitting for individual CCA patient management and chemotherapeutic selection.…”
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325
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome.
Published 2015-01-01“…Finally, gene set enrichment analysis (GSEA) was used as a feature selection technique for input into a support vector machine (SVM) classifier. …”
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326
Identification of Gene Modules Associated with Low Temperatures Response in Bambara Groundnut by Network-Based Analysis.
Published 2016-01-01“…Therefore, in this study we developed a computational pipeline to identify and analyze the genes and gene modules associated with low temperature stress responses in bambara groundnut using the cross-species microarray technique (as bambara groundnut has no microarray chip) coupled with network-based analysis. …”
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327
Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion.
Published 2015-01-01“…CSTA is deregulated in several skin cancers, including squamous cell carcinomas (SCC) and loss of function mutations lead to recessive skin fragility disorders. The microarray results were confirmed by qPCR, immunoblotting, and immunohistochemistry. …”
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328
Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay
Published 2018-01-01“…After treatment with pioglitazone for 11 weeks, the effects on fasting blood glucose, body weight, and blood biochemistry parameters were evaluated. …”
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329
Molecular characterization of adipose tissue in the African elephant (Loxodonta africana).
Published 2014-01-01“…RNA was extracted and histological sections created and analyzed by microarray, PCR and immunohistochemistry respectively. …”
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330
miRNA-REGULATED PATHWAYS OF CD8+ T CELLS IN TNBC MOUSE MODEL
Published 2022-08-01“…Following RNA isolation, miRNA microarray analysis was performed. Differentially expressed miRNAs between the groups were detected. …”
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331
Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia
Published 2025-04-01“…To verify this differentiation-switching technique, we obtained microarray data comparing each differentiation state. …”
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332
Immune-related gene characterization and biological mechanisms in major depressive disorder revealed based on transcriptomics and network pharmacology
Published 2024-12-01“…Subsequently, gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Cytoscape plugin CluGO, and Gene Set Enrichment Analysis (GSEA) were utilized to identify immune-related genes. The final selection of immune-related hub genes was determined through the least absolute shrinkage and selection operator (Lasso) regression analysis and PPI analysis. …”
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333
Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health
Published 2025-04-01“…We critically evaluate previous DNA methylation biomarker studies, particularly those using microarray platforms, and advocate for a shift towards sequencing-based approaches to improve genome-wide coverage. …”
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334
Transcriptional changes during hepatic ischemia-reperfusion in the rat.
Published 2019-01-01“…There are few effective targeted strategies to reduce hepatic ischemia-reperfusion (IR) injury, a contributor to poor outcomes in liver transplantation recipients. …”
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335
Expression and Promoter Analysis of Six Heat Stress-Inducible Genes in Rice
Published 2013-01-01“…Six highly heat responsive genes were identified in rice by microarray data analysis. The qRT-PCR analysis confirmed that the expression of these six genes were highly heat inducible and moderately responded to salt stress, polyethylene glycol, and abscisic acid treatment, but little affected by cold treatment. …”
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336
Comprehensive analysis of intervention and control studies for the computational identification of dengue biomarker genes.
Published 2025-03-01“…Despite significant progress in understanding Dengue fever, effective prognosis and treatment remain elusive due to the complex clinical presentations and limitations in current diagnostic methods. …”
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337
Upregulated interleukin‐6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma
Published 2015-08-01“…Mechanisms of acquired resistance to the EGFR TKI erlotinib was investigated by developing erlotinib‐resistant HNSCC cell lines and comparing their gene expression profiles with their parental erlotinib‐sensitive HNSCC cell lines using microarray analyses and subsequent pathway and network analyses. …”
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338
Potential application of the bulk RNA sequencing in routine MPN clinics
Published 2025-04-01“…Additionally, data from the microarray datasets [GSE26049, GSE2191] were included in this study. …”
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339
Mutation Spectrum of the ABCA4 Gene in a Greek Cohort with Stargardt Disease: Identification of Novel Mutations and Evidence of Three Prevalent Mutated Alleles
Published 2018-01-01“…A total of 59 patients were analyzed for ABCA4 mutations using the ABCR400 microarray and PCR-based sequencing of all coding exons and flanking intronic regions. …”
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340
Transcriptomic profile induced by calcitriol in CaSki human cervical cancer cell line.
Published 2025-01-01“…We examined the transcriptional changes induced by calcitriol in CaSki cells, a cervical cell line harboring multiple copies of HPV16, the primary causal agent of cervical cancer. Our microarray findings, revealed that calcitriol regulated over 1000 protein-coding genes, exhibiting a predominantly repressive effect on the CaSki cell transcriptome by suppressing twice as many genes as it induced. …”
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