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Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Current research is focused on identifying effective treatments for PTSD. Advances in bioinformatics provide opportunities to elucidate the underlying mechanisms of PTSD. …”
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122
Possibility of the Use of Public Microarray Database for Identifying Significant Genes Associated with Oral Squamous Cell Carcinoma
Published 2012-03-01“…Most studies include insufficient samples to apply statistical methods for detecting significant gene sets. This study combined two small microarray datasets from a public database and identified significant genes associated with the progress of oral squamous cell carcinoma. …”
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123
Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer
Published 2015-01-01“…Using carbohydrate microarrays, we explored potential natural ligands of antitumor monoclonal antibody HAE3. …”
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A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis.
Published 2016-01-01“…In the present study, we performed DNA microarray analysis to investigate the effects of a HP diet on the liver, which plays a pivotal role in energy metabolism. …”
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127
Development of a microarray based telomerase binding assay reveals unusual binding of a cytochalasin derivative
Published 2025-06-01“…In this study, we present a highly miniaturized, microarray-based assay designed to identify compounds that target telomerase. …”
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128
Improving machine learning detection of Alzheimer disease using enhanced manta ray gene selection of Alzheimer gene expression datasets
Published 2025-08-01“…To alleviate such an effect, this study proposes a gene selection approach based on the parameter-free and large-scale manta ray foraging optimization algorithm. …”
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129
In Vitro Investigation of Statin Effects on Genes Associated with Severe COVID-19 in Cancerous and Non-Cancerous Cells
Published 2025-07-01“…However, statins exhibit additional pleiotropic effects. The present study aims to investigate the effects of all eight currently existing statins on the expression of genes whose products have been reported to be directly associated with complicated COVID-19 disease. …”
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130
Utilizing Machine Learning Techniques for Cancer Prediction and Classification based on Gene Expression Data
Published 2025-06-01“…Lately, several studies have delved into cancer classification by leveraging data mining techniques, machine learning algorithms, and statistical methods to thoroughly analyze high-dimensional datasets. Detecting cancer early by examining gene expression data is vital for providing effective patient care. …”
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Genetic findings of children with congenital heart diseases using chromosomal microarray and trio-based whole exome sequencing
Published 2025-07-01“…In individuals with extracardiac features, the overall detection rate was significantly higher (61.5%) than in individuals with isolated CHD (17.3%) (P = 4.6 × 10− 3). …”
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132
Gene Expression Profile of Dendritic Cell-Tumor Cell Hybrids Determined by Microarrays and Its Implications for Cancer Immunotherapy
Published 2015-01-01“…Dendritic cell- (DC-) tumor fusion cells stimulate effective in vivo antitumor responses. However, therapeutic approaches are dependent upon the coadministration of exogenous 3rd signals. …”
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133
Deciphering the prokaryotic community and metabolisms in South African deep-mine biofilms through antibody microarrays and graph theory.
Published 2014-01-01“…Both culture-independent techniques coincided in detecting features related to aerobic sulfur-oxidizers, aerobic chemoorganotrophic Alphaproteobacteria and metanotrophic Gammaproteobacteria. 16S rRNA gene sequencing detected phylotypes related to nitrate-reducers and anaerobic sulfur-oxidizers, whereas the EMChip66 detected immunological features from methanogens and sulfate-reducers. …”
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A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases
Published 2025-01-01“…The diagnostic tests currently available for tick-borne diseases are severely limited in their ability to provide accurate results and cannot detect multiple pathogens in a single run. The multiplex protein microarray developed at Vibrant was designed to detect multiple serological antibodies thereby detecting exposure to multiple pathogens simultaneously. …”
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IDENTIFYING IMPORTANT GENES IN OVARIAN CANCER FROM HIGH-DIMENSIONAL MICROARRAY DATA USING SIFS-CART METHOD
Published 2024-07-01“…Ovarian cancer can be identified from microarray data using machine learning. Many studies only focus on improving the machine learning classification algorithms to achieve higher performance. …”
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No Amplifications of Hypoxia-Inducible Factor-1α Gene in Invasive Breast Cancer: A Tissue Microarray Study
Published 2004-01-01“…Methods: Protein and gene expression of HIF‐1α were analyzed on a tissue microarray of 94 breast cancers by immunohistochemistry and fluorescent in situ hybridization (FISH), respectively. …”
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137
Mapping quantitative trait loci regions associated with Marek’s disease on chicken autosomes by means of selective DNA pooling
Published 2024-12-01“…Distribution of P and LD values were used to assess the QTLR causative elements. Allele substitution effects were calculated based on both pooled SNP microarray genotypes, and individual genotypes of QTLRs markers. …”
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PD-L1 quantification across tumor types using the reverse phase protein microarray: implications for precision medicine
Published 2021-10-01“…Using a high throughput immunoassay, the reverse phase protein microarray (RPPA), coupled with a fluorescence-based detection system, this study compared the performance of six anti-PD-L1 antibody clones on 666 tumor samples.Methods PD-L1 expression was measured using five antibody clones (22C3, 28–8, CAL10, E1L3N and SP142) and the therapeutic antibody atezolizumab on 222 lung, 71 ovarian, 52 prostate and 267 breast cancers, and 54 metastatic lesions. …”
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Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses
Published 2025-04-01“…PD diagnosis depends on clinical manifestation of symptoms but is lack of effective biomarker.MethodsAvailable human microarray-based transcriptomic datasets of the substantia nigra and blood were acquired for PD cases and controls. …”
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