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801
Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas
Published 2012-01-01“…A cytoplasmic β-catenin pool was detectable in 13/15 cultures leading to some transcriptional activity assessed by luciferase reporter gene assay in 8/13. …”
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802
Over Time Changes in the Transcriptomic Profiles of Tomato Plants with or Without <i>Mi-1</i> Gene During Their Incompatible or Compatible Interactions with the Whitefly <i>Bemisia...
Published 2025-03-01“…Motelle, incompatible interaction) was studied using the oligonucleotide microarray technique. Both interactions were studied 2 and 12 days post infestation (dpi) of plants with adult insects. …”
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803
Genetic and functional characterization of inherited complex chromosomal rearrangements in a family with multisystem anomalies
Published 2025-01-01“…They often require karyotyping, fluorescence in situ hybridization, and chromosomal microarray analysis (CMA) for clinical diagnosis because of the limitations of each method. …”
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804
Molecular profiles of tumor contrast enhancement: A radiogenomic analysis in anaplastic gliomas
Published 2018-09-01“…Gene set enrichment analysis (GSEA), significant analysis of microarray, generalized linear models, and Least absolute shrinkage and selection operator algorithm were used to explore radiogenomic and prognostic signatures of AG patients. …”
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805
Bioinformatic analyses reveal lysosomal-associated protein transmembrane 5 as a potential therapeutic target in lipotoxicity-induced injury in diabetic kidney disease
Published 2024-12-01“…Here, we analyzed the GSE 30529 microarray datasets of human tubulointerstitial tissue samples from the Gene Expression Omnibus database (GEO). …”
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806
Identification and validation of hub genes associated with biotic and abiotic stresses by modular gene co-expression analysis in Oryza sativa L.
Published 2025-03-01“…A total of 11, 12, 46, and 14 modules containing 85, 106, 253, and 143 hub genes were detected in drought, salinity, tungro virus, and blast. …”
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807
Expression and clinical significance of FGL1 and YAP1 in colorectal cancer
Published 2025-07-01“…<b>Methods</b> Tissue microarray technique was used to detect FGL1 and YAP1 expression in 101 colorectal cancer tissues and 79 adjacent tissues from June 2007 to April 2008. …”
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808
Identifying a unique chromosomal pattern to predict the gemcitabine response in patients with cholangiocarcinoma
Published 2025-04-01“…To predict the response to GEM, we evaluated chromosomal aberrations using a chromosome microarray, and their association with GEM response by histoculture drug response assay. …”
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809
Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma
Published 2025-04-01“…Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers. …”
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810
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome.
Published 2015-01-01“…Finally, gene set enrichment analysis (GSEA) was used as a feature selection technique for input into a support vector machine (SVM) classifier. …”
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811
Screening and identification of potential target of 1′-acetoxychavicol acetate (ACA) in acquired lapatinib-resistant breast cancer
Published 2024-12-01“…Genomic mutations, expression levels, prognostic significance, and ROC analysis were examined in selected genes. We used AutoDock Vina to conduct ACA molecular docking with potential target genes. …”
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812
Bayesian inference towards the resolution of molecular evolution: application to the “Trichoderma harzianum sensu lato” clade
Published 2004-07-01“…The clade containing the ex-neotype strain of T. harzianum included exclusively clonally propagating isolates from temperate climates, and was clearly distinguished from all other “H. lixii/T. harzianum” lineages by multivariate analysis of phenotype microarray data. We propose that only this lineage should be regarded as T. harzianum sensu stricto, and that the other lineages be regarded as T. harzianum sensu lato until phenetic characters have been defined which allow their description as separate taxa.…”
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813
New Frontiers for the Early Diagnosis of Cancer: Screening miRNAs Through the Lateral Flow Assay Method
Published 2025-04-01“…This review focuses on LFA-based methods for detecting and quantifying miRNAs associated with the diagnosis of various cancers, with particular emphasis on sensitivity enhancements achieved through the application of different labels and detection systems. …”
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814
Differentiating Branch Duct and Mixed IPMN in Endoscopically Collected Pancreatic Cyst Fluid via Cytokine Analysis
Published 2012-01-01“…Eighty-six of 89 IMPs were detected in at least one of the 10 samples. Fourteen IMPs were detected only in mixed IPMN, while none were only in BD-IPMN. …”
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815
Myogenic IGFBP5 levels in rhabdomyosarcoma are nourished by mesenchymal stromal cells and regulate growth arrest and apoptosis
Published 2025-04-01“…High resolution microarray-based Clariom D gene expression analysis identified insulin-like growth factor binding protein 5 (IGFBP5) as the top upregulated gene in RMS cells exposed to naïve stromal cells, and effects on growth arrest, caspase 3/7 activation, and myogenic cell identity were demonstrated in functional assays. …”
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816
Coexpression within Integrated Mitochondrial Pathways Reveals Different Networks in Normal and Chemically Treated Transcriptomes
Published 2014-01-01“…In this study, we construct coexpression networks based on microarray datasets from different tissues and chemical treatments to explore the role of integrated MRCs in the coexpression network and the effects of different chemicals on the mitochondrial network. …”
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817
Brachyury promotes proliferation and migration of colorectal cancer cells by targeting MMP14
Published 2025-04-01“…Although the transcription factor, Brachyury is intricately linked with various clinical malignancies, the mechanisms by which it influences CRC cell proliferation and migration are inadequately understood. Methods Tissue microarray was used to evaluate Brachyury expression in CRC and adjacent normal tissues. …”
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818
HVEM as a tumor-intrinsic regulator in non-small cell lung cancer: Suppression of metastasis via glycolysis inhibition and modulation of macrophage polarization
Published 2025-03-01“…In this study, We demonstrated that CK+HVEM+ tumor correlates with better survival using Multiplex immuno histochemistry (mIHC) in Human Lung Adenocarcinoma Tissue microarray. Next, we showed that HVEM knockdown promoted NSCLC cell invasion and metastasis in vitro whereas exhibited no effect on proliferation. …”
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819
Bidirectional Transcriptome Analysis of Rat Bone Marrow-Derived Mesenchymal Stem Cells and Activated Microglia in an In Vitro Coculture System
Published 2018-01-01“…Bone marrow-derived mesenchymal stem cells (BM-MSCs) have been shown to have therapeutic effects, resulting from the regulation of inflammatory conditions in the brain. …”
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820
The potential radiosensitization target PFKFB3 is related to response to radiotherapy in SweBCG91RT: a randomized clinical trial with long-term follow-up
Published 2025-02-01“…Methods Nuclear protein levels of PFKFB3 were assessed with immunohistochemistry in primary breast tumors (n = 970) and whole-cell RNA levels with microarray gene expression (n = 765). Multivariable competing risks regression analysis was employed for the effect of radiotherapy on incidence of ipsilateral breast tumor recurrence (IBTR), depending on PFKFB3 levels. …”
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