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Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression
Published 2009-10-01Get full text
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A standardized fold change method for microarray differential expression analysis used to reveal genes involved in acute rejection in murine allograft models
Published 2018-03-01“…We suggest that SFC can be utilized to stably and effectively detect differential gene expression and to explore microarray data in further studies.…”
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A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma.
Published 2013-01-01“…This shows superior survival separation for assigned Activated B-cell (ABC) and Germinal Center B-cell (GCB) DLBCL classes relative to a range of other classifiers. DAC is effective on data derived from multiple microarray platforms and formalin fixed paraffin embedded samples and is parsimonious, using 20 classifier genes. …”
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Using machine learning to discover DNA metabolism biomarkers that direct prostate cancer treatment
Published 2025-07-01Get full text
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Copula-Based Bayesian Model for Detecting Differential Gene Expression
Published 2025-04-01“…Finally, we apply our model to <i>Escherichia coli</i> microarray data, illustrating its practical utility in gene expression analysis.…”
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127
Higher expression of mir‐31‐5p is associated with reduced risk of head and neck keloid recurrence following surgical resection
Published 2024-12-01“…Methods Using a tissue microarray, mir‐31‐5p expression was measured with miRNAscope, and mir‐31‐5p cell positivity was determined with QuPath. …”
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Evaluating methods for identifying and quantifying Streptococcus pneumoniae co-colonization using next-generation sequencing data
Published 2024-12-01“…Across the 24 individuals, the microarray detected 77 non-unique serotypes, of which 42 occurred at high relative abundance (>10%) (per individual, median, 3; range, 1–6 serotypes). …”
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129
Dissection of a complex transcriptional response using genome‐wide transcriptional modelling
Published 2009-11-01“…We examined the transcriptional response to DNA damage in a human T cell line (MOLT4) using microarrays. By measuring both mRNA accumulation and degradation over a short time course, we were able to construct a mechanistic model of the transcriptional response. …”
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Genome-wide profiling of micro-RNA expression in gefitinib-resistant human lung adenocarcinoma using microarray for the identification of miR-149-5p modulation
Published 2017-03-01“…We compared the micro-RNA expression profiles of the HCC827 cells HCC827/GR-8-1 using Agilent micro-RNA microarrays. The micro-RNAs, such as the miR-149-5p, were up- or downregulated and associated with acquired gefitinib resistance. …”
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Investigation of local corrosion behavior and mechanism for TA2/HAl77-2/316L SS coupling systems under seawater liquid film
Published 2025-02-01“…Local corrosion parameters, such as the maximum potential difference (ΔEmax), the maximum anode current density (Ia,max), the local corrosion intensity factor (LCII), and the cathode to anode area ratio (Sc/Sa) were obtained to quantitatively characterize the local corrosion degree of microarray electrodes. The results showed that HAl77-2 and most of the 316L SS electrode wires in the microarray electrodes served as anodes, while TA2 and the remainder of the 316L SS electrode wires performed as cathodes. …”
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Exposing Optimal Feature Sets for Enhancing Machine Learning Performance
Published 2025-01-01“…The opposition based learning (OBL) technique is used to mitigate the risk of CSA converging towards local optima. To evaluate the effectiveness of our approach, we conduct experiments on benchmark microarray datasets from the ADNI database. …”
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SINGLE NUCLEOTIDE POLYMORPHISMS IN BREAST TUMOR AND EXPRESSION OF ABC-TRANSPORTERS AFTER NEOADJUVANT CHEMOTHERAPY
Published 2016-02-01“…Using a quantitative Real-time PCR, the expression of 4 multidrug resistence (MDR) genes (ABCB1, ABCC1, ABCC2, ABCG2) was studied in surgical samples after NAC. Microarray analysis was performed using high density DNA microarrays, which contain more than 750.000 SNPs. …”
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Search for polymorphic variants of candidate genes contributing to individual radiosensitivity
Published 2023-01-01“…DNA was genotyped using 257 SNPs of cyclin genes and neighboring intergenic regions using DNA microarrays from the high-density CytoScan HD Array (Affymetrix, USA).Results. …”
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Role of transcriptomics in the study of oral cancer
Published 2025-07-01“…We delve into RNA sequencing (RNA-seq), single-cell RNA sequencing (scRNA-seq), long non-coding RNA sequencing (lncRNA-seq), microarray analysis, and small RNA profiling, showcasing their unique contributions to unraveling the complexities of oral cancer. …”
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Genetic testing for diagnosing neurodevelopmental disorders and epilepsy: a systematic review and meta-analysis
Published 2025-07-01“…Abstract Background Identifying the genetic causes of neurodevelopmental disorders (NDDs) and epilepsy is crucial for effective treatment and genetic counseling. Our objective was to determine the diagnostic yield of chromosomal microarray (CMA) and next-generation sequencing (NGS) methods—including targeted sequencing (TS), whole-exome sequencing (WES), and whole-genome sequencing (WGS)—in individuals with NDDs or epilepsy. …”
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