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Phenotype microarray-based assessment of metabolic variability in plant protoplasts
Published 2025-05-01“…Conclusions The standardized high-throughput system developed was effective for the metabolic characterization of plant protoplasts. …”
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82
Inflammatory Pathways in Parkinson’s Disease; A BNE Microarray Study
Published 2012-01-01“…The main focus of PD research is to better understand substantia nigra homeostasis disruption, particularly in relation to the wide-spread deposition of the aberrant protein α-synuclein. Microarray technology contributed towards PD research with several studies to date and one gene, ALDH1A1 (Aldehyde dehydrogenase 1 family, member A1), consistently reappeared across studies including the present study, highlighting dopamine (DA) metabolism dysfunction resulting in oxidative stress and most probably leading to neuronal cell death. …”
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83
A Novel Feature Selection Method for Classification of Medical Data Using Filters, Wrappers, and Embedded Approaches
Published 2022-01-01“…For this purpose, the proposed research focused on analyzing and identifying effective feature selection algorithms. A novel framework is proposed which utilizes different feature selection methods from filters, wrappers, and embedded algorithms. …”
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84
Enhanced leukemia prediction using hybrid ant colony and ant lion optimization for gene selection and classification
Published 2025-06-01“…Gene selection plays a crucial role in the pre-processing of microarray data, aiming to identify a small set of genes that enhances classification accuracy and reduces costs. …”
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85
Implementation of NGS and SNP microarrays in routine forensic practice: opportunities and barriers
Published 2025-05-01“…NGS enables STR sequencing and SNP typing with enhanced discriminatory power, better performance with degraded DNA, and improved mixture deconvolution. Conversely, SNP microarrays offer a cost-effective solution for extended kinship testing, Forensic Investigative Genetic Genealogy (FIGG), and phenotypic prediction, though they are less effective with low-quality samples and DNA mixtures. …”
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Microarray integrated spatial transcriptomics (MIST) for affordable and robust digital pathology
Published 2024-11-01“…To address these issues, we propose Microarray Integrated Spatial Transcriptomics (MIST), combining conventional tissue microarray (TMA) with Visium, using laser-cutting and 3D printing to enhance slide throughput. …”
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88
Gene expression analysis of ABC transporter family in breast tumors: relationship with chemotherapy effect and disease prognosis
Published 2020-09-01“…RNA was isolated from paired samples of tumor tissue before and after NAC. A microarray study of all tumor samples was performed on ClariomТМ S Assay, human microarrays. …”
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A Meta‐Analysis of the Effects of Early Life Stress on the Prefrontal Cortex Transcriptome Reveals Long‐Term Downregulation of Myelin‐Related Gene Expression
Published 2025-06-01“…For each gene, a random‐effects meta‐analysis model was then fit to the ELS versus control effect sizes (Log2 Fold Changes) from each study. …”
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91
A review of independent component analysis application to microarray gene expression data
Published 2008-11-01“…Independent component analysis (ICA) methods have received growing attention as effective data-mining tools for microarray gene expression data. …”
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92
Identification of the feline humoral immune response to Bartonella henselae infection by protein microarray.
Published 2010-07-01“…Understanding the complex interactions between the host's immune system and bacterial pathogens is central to the field of infectious diseases and to the development of effective diagnostics and vaccines.<h4>Methodology</h4>We report the development of a microarray comprised of proteins expressed from 96% (1433/1493) of the predicted ORFs encoded by the genome of the zoonotic pathogen Bartonella henselae. …”
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93
Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications
Published 2011-01-01“…The microarray evidences of molecular basis of obesity and insulin resistance are presented here. …”
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94
Enucleation-Induced Rat Adrenal Gland Regeneration: Expression Profile of Selected Genes Involved in Control of Adrenocortical Cell Proliferation
Published 2014-01-01“…Factors encoded by these genes obscure possible priming effects of various cytokines on initiation of regeneration. …”
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Improving machine learning detection of Alzheimer disease using enhanced manta ray gene selection of Alzheimer gene expression datasets
Published 2025-08-01“…To alleviate such an effect, this study proposes a gene selection approach based on the parameter-free and large-scale manta ray foraging optimization algorithm. …”
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96
Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing
Published 2025-07-01“…Abstract Background Chromosomal microarray analysis (CMA) is being increasingly used to reveal the genetic causes of miscarriage. …”
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97
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
Published 2012-01-01“…Transcriptional profiling by cDNA microarray combined with reverse genetics revealed phosphorylation of the eukaryotic initiation factor 2-alpha (EIF2A) through the eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3/PERK) as the mechanism of action of this compound. …”
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Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.
Published 2010-07-01“…<h4>Background</h4>Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. …”
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Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray
Published 2015-01-01“…With the recent development of biotechnologies, cDNA microarray chips are increasingly applied in cancer research. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer
Published 2025-02-01“…Transfection efficiency was confirmed via qRT-PCR in HCT116 and SW480 colon cells, and the effects of circDOCK1 on cell proliferation, migration, and invasion were assessed.ResultsMicroarray data revealed 149 significantly differentially expressed circRNAs, including 71 upregulated and 78 downregulated circRNAs, in CRC tissues. …”
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