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241
Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y.
Published 2013-01-01“…Functional analyses do not fully explain the selective pressure causing ERG rearrangement during the development of prostate cancer. …”
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242
Integrated analysis of hub genes and intrinsically disordered regions in triple-negative breast cancer
Published 2024-12-01“…Two microarray datasets were used to identify possible targets for TNBC, GSE38959 and GSE45827, retrieved from the Gene Expression Omnibus (GEO) database. …”
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243
Regulation of neutrophil senescence by microRNAs.
Published 2011-01-01“…Total RNA from highly purified neutrophils was prepared and subjected to microarray analysis using the Agilent human miRNA microarray V3. …”
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244
Differentially expressed circular RNAs and their diagnostic value in children with allergic rhinitis
Published 2025-08-01“…Methods Blood samples were collected from allergic rhinitis patients and healthy controls, and circular RNA microarray was performed. The expression of differentially expressed circular RNAs was verified via real-time quantitative reverse transcription polymerase chain reaction, and these RNAs were selected for Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses. …”
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245
Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms
Published 2025-08-01“…ObjectiveTo construct a diagnostic model of osteoarthritis related to methylation genes using machine learning algorithms, and analyze its prognostic value and biological functions.MethodsThe GSE 63695 and GSE162484 datasets including human osteoarthritis (OA) and normal samples were downloaded from the GEO datasets. The microarray chip data of chondrocytes were analyzed using R software to obtain differentially methylated genes. …”
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246
Identification of G1-regulated genes in normally cycling human cells.
Published 2008-01-01“…<h4>Methodology and findings</h4>We used a robotic mitotic shake-off apparatus to select cells in late mitosis for genome-wide gene expression studies. …”
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247
Exploring Flexible Penalization of Bayesian Survival Analysis Using Beta Process Prior for Baseline Hazard
Published 2025-01-01“…Moreover, in microarray research, it is common to identify groupings of genes involved in the same biological pathways. …”
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248
Exploration of autophagy-related molecular mechanisms underlying epilepsy using multiple datasets
Published 2025-08-01“…Methods We analyzed GSE143272 and GSE4290 microarray datasets from the NCBI Gene Expression Omnibus database, which is established based on evaluations of peripheral blood samples. …”
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249
Integrated analysis of genomic and transcriptomic profiles identified a prognostic immunohistochemistry panel for esophageal squamous cell cancer
Published 2020-01-01“…Methods An integrated analysis was performed to screen and establish a prognostic panel using exome sequencing profile from 81 pairs of ESCC samples and RNA expression microarray data from 119 ESCC subjects. Two independent ESCC cohorts were recruited as training and validation groups to test the prognostic value. …”
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250
Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression
Published 2025-05-01“…Methods TNBC-related datasets were retrieved from The Cancer Genome Atlas and selected by Prediction Analysis of Microarray 50 analysis to assess the expression of PMAIP1 in the samples. …”
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251
Expression of Genes Related to Germ Cell Lineage and Pluripotency in Single Cells and Colonies of Human Adult Germ Stem Cells
Published 2016-01-01“…Genome-wide comparisons with microarray analysis confirmed that different haGSC colonies exhibited gene expression heterogeneity with more or less pluripotency. …”
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252
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.
Published 2011-01-01“…In order to obtain a global view of the impact of Snail and Slug expression, we performed a microarray experiment using the MCF-7 breast cancer cell line, which does not express detectable levels of Snail or Slug. …”
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253
Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.
Published 2008-02-01“…Pre-treatment of rats with a selective inhibitor of Stat3, T40214, reduced the IL-6-mediated increase in cardiac Stat3 activity, blocked successful resuscitation by IL-6 and reversed IL-6-mediated protection from cardiac apoptosis. …”
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254
Transcriptional Profile of Kidney from Type 2 Diabetic db/db Mice
Published 2017-01-01“…We explored changes in the transcriptional profile in spontaneous type 2 diabetic db/db mice by using the cDNA microarray. Compared with control db/m mice, the db/db mice exhibited marked increases in body weight, kidney weight, and urinary albumin excretion. …”
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255
Identification of Differentially Expressed Genes and Long Noncoding RNAs Associated with Parkinson’s Disease
Published 2019-01-01“…This study aims to determine differentially expressed genes (DEGs) and long noncoding RNAs (lncRNAs) associated with Parkinson’s disease (PD) using a microarray. Methods. We downloaded the microarray data GSE6613 from the Gene Expression Omnibus, which included 105 samples. …”
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256
Transcriptional profiling of nitrogen fixation and the role of NifA in the diazotrophic endophyte Azoarcus sp. strain BH72.
Published 2014-01-01“…<h4>Methodology/principal findings</h4>A DNA microarray, comprising 70-mer oligonucleotides representing 3989 open reading frames of the genome of strain BH72, was used for transcriptome studies. …”
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257
Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.
Published 2012-06-01“…Single-nucleotide polymorphisms (SNPs) selected from a recent meta-analysis of PD genome-wide association studies (GWAS) were successfully genotyped in 50 out of the 53 microarray brains, allowing a targeted expression-SNP (eSNP) analysis for 52 SNPs associated with PD affection at genome-wide significance and the 189 probes from FoxO1 regulated genes. …”
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258
Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
Published 2018-01-01“…Methods. lncRNA and mRNA profiling of PBMCs from 17 smokers and 14 COPD subjects was detected by high-throughput microarray. The expression of dysregulated lncRNAs was validated by qPCR. …”
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259
Multiple colonization with S. pneumoniae before and after introduction of the seven-valent conjugated pneumococcal polysaccharide vaccine.
Published 2010-07-01“…Serotypes were identified by agglutination, multiplex PCR and microarray.<h4>Principal findings</h4>Rate of multiple colonization remained stable up to three years after PCV7 introduction. …”
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260
Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation
Published 2025-05-01“…The levels of anti-CRP and SLE-associated antibodies were assessed, and a microarray-based linear epitope mapping was performed to detect binding sites on the full CRP monomer. …”
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