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QCanvas: An Advanced Tool for Data Clustering and Visualization of Genomics Data
Published 2012-12-01Get full text
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Tissue‐based quantitative proteomics to screen and identify the potential biomarkers for early recurrence/metastasis of esophageal squamous cell carcinoma
Published 2018-06-01“…Thirteen proteins were selected by cutoff value of 0.67 fold for underexpression and 1.5‐fold for overexpression. …”
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Differential gene expression analysis in patients with primary hyperhidrosis
Published 2025-02-01“…Based on the highest expression of ITPR2 in hyperhidrosis, it was selected for PCR amplification as well as sequencing. …”
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Mapping quantitative trait loci regions associated with Marek’s disease on chicken autosomes by means of selective DNA pooling
Published 2024-12-01“…Distribution of P and LD values were used to assess the QTLR causative elements. Allele substitution effects were calculated based on both pooled SNP microarray genotypes, and individual genotypes of QTLRs markers. …”
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Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella
Published 2025-05-01“…An ideal vaccine would provide protection against the most prevalent species, Shigella flexneri and Shigella sonnei; therefore, it could be relevant to identify common antigens. We developed a microarray containing 3,150 full-length or fragmented proteins selected across Shigella species. …”
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Genetic feature selection algorithm as an efficient glioma grade classifier
Published 2025-05-01“…Genetic testing is a rapidly evolving modality for cancer management. The advent of DNA microarrays enabled the utility of computational analyses in such management on a molecular basis. …”
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Effects of oxidized phospholipids on gene expression in RAW 264.7 macrophages: a microarray study.
Published 2014-01-01“…In this study we present the effects of 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine (PGPC) and 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) on gene expression in RAW 264.7 macrophages using cDNA microarrays. …”
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CFS-MOES Ensemble Model on Metaheuristic Search-Based Feature Selection
Published 2024-01-01“…The application of several classification and feature selection methods on microarray gene expression datasets helps learn models that are able to predict a given disease. …”
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Expression of long non-coding RNA in patients with non-IgA mesangial proliferative glomerulonephritis
Published 2015-01-01“…Objective To study differential expression profile of mRNA and long non-coding RNA(IncRNA) through microarray analysis between non-IgA mesangial proliferative glomerulonephritis(MsPGN) patients and the controls,and then explore the potential role of IncRNA in the pathogenesis of non-IgA MsPGN.Methods Through simple random sampling,4 patients with non-IgA MsPGN and 2 controls were selected as disease group and control group,respectively.Renal cortical tissues from two groups were collected.Total RNA was extracted,quantified and prepared to ds-cDNA through reverse transcription ds-cDNA was labeled with NimbleGen one-color DNA labeling kit and used for array hybridization.All experimental data were processed through GO analysis,Pathway analysis and the gene loci correlation analysis of mRNA and IncRNA.Some IncRNAs that were closely related to non-IgA MsPGN were screened out.Finally,part of the array results was detected by PCR to verify the reliability of array test Results By fold change filtering,4317 differentially expressed mRNAs and 3502 differentially expressed IncRNAs were screened out.Five IncRNAs were found to play potential roles in the pathogenesis of non-IgA MsPGN:AF1180924(close to coding gene FGG),AK092233(close to coding gene COL18A1),AK130579(close to coding gene CREBBP),AK023598(close to coding gene LEPR),and AK055915(close to coding gene CDC42EP3).These results provided an important basis for revealing the pathogenesis of non-IgA MsPGN.Conclusions Some IncRNAs can potentially regulate related genes and plays an important role in the pathogenesis and development of non-IgA MsPGN.…”
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A Highly Discriminative Hybrid Feature Selection Algorithm for Cancer Diagnosis
Published 2022-01-01“…To examine the proposed algorithm, many tests have been carried out on four cancerous microarray datasets, employing in the process 10-fold cross-validation and hyperparameter tuning. …”
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Microarray analysis of the effects of Acthar Gel versus methylprednisolone in a model of focal segmental glomerulosclerosis in female rats
Published 2025-04-01“…On Day 56, animals were sacrificed, and RNA samples of kidney cortex tissue were analyzed using microarrays. Compared with control, Acthar significantly decreased the expression of more genes related to inflammation, immune function, and fibrosis than MP. …”
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A Comparative Analysis of Swarm Intelligence Techniques for Feature Selection in Cancer Classification
Published 2014-01-01“…Feature selection in cancer classification is a central area of research in the field of bioinformatics and used to select the informative genes from thousands of genes of the microarray. …”
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RETRACTED ARTICLE: Multi-stage biomedical feature selection extraction algorithm for cancer detection
Published 2023-04-01“…Early cancer detection is greatly aided by machine learning and artificial intelligence (AI) to gene microarray data sets (microarray data). Despite this, there is a significant discrepancy between the number of gene features in the microarray data set and the number of samples. …”
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Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes
Published 2001-02-01“…Our method provides a cost-effective alternative to conventional attachment strategies that is particularly suitable for genotyping PCR products with nucleic acid microarrays.…”
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Fast Spot Locating for Low-Density DNA Microarray
Published 2025-03-01“…Low-density DNA microarrays are crucial in molecular diagnostics due to their cost-effectiveness and high sensitivity. …”
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An efficient leukemia prediction method using machine learning and deep learning with selected features.
Published 2025-01-01“…The suggested work predicts and classifies leukemia subtypes in gene data CuMiDa (GSE9476) using feature selection and ML techniques. The Curated Microarray Database (CuMiDa) collected 64 samples representing five classes of leukemia genes out of 22283 genes. …”
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Drug and cell type-specific regulation of genes with different classes of estrogen receptor beta-selective agonists.
Published 2009-07-01“…U2OS cells stably transfected with ERalpha or ERbeta were treated with E(2) or the ERbeta-selective compounds for 6 h. Microarray data demonstrated that ERB-041, MF101 and liquiritigenin were the most ERbeta-selective agonists compared to estradiol, followed by nyasol and then diarylpropionitrile. …”
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