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421
c-Triadem: A constrained, explainable deep learning model to identify novel biomarkers in Alzheimer's disease.
Published 2025-01-01“…We trained the model with blood genotyping data, microarray, and clinical features from the Alzheimer's Neuroimaging Disease Initiative (ADNI). …”
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422
Identification of Gene Modules Associated with Low Temperatures Response in Bambara Groundnut by Network-Based Analysis.
Published 2016-01-01“…Therefore, in this study we developed a computational pipeline to identify and analyze the genes and gene modules associated with low temperature stress responses in bambara groundnut using the cross-species microarray technique (as bambara groundnut has no microarray chip) coupled with network-based analysis. …”
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423
Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion.
Published 2015-01-01“…CSTA is deregulated in several skin cancers, including squamous cell carcinomas (SCC) and loss of function mutations lead to recessive skin fragility disorders. The microarray results were confirmed by qPCR, immunoblotting, and immunohistochemistry. …”
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424
Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay
Published 2018-01-01“…After treatment with pioglitazone for 11 weeks, the effects on fasting blood glucose, body weight, and blood biochemistry parameters were evaluated. …”
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425
Molecular characterization of adipose tissue in the African elephant (Loxodonta africana).
Published 2014-01-01“…RNA was extracted and histological sections created and analyzed by microarray, PCR and immunohistochemistry respectively. …”
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426
miRNA-REGULATED PATHWAYS OF CD8+ T CELLS IN TNBC MOUSE MODEL
Published 2022-08-01“…Following RNA isolation, miRNA microarray analysis was performed. Differentially expressed miRNAs between the groups were detected. …”
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427
Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia
Published 2025-04-01“…To verify this differentiation-switching technique, we obtained microarray data comparing each differentiation state. …”
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428
Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health
Published 2025-04-01“…We critically evaluate previous DNA methylation biomarker studies, particularly those using microarray platforms, and advocate for a shift towards sequencing-based approaches to improve genome-wide coverage. …”
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429
Transcriptional changes during hepatic ischemia-reperfusion in the rat.
Published 2019-01-01“…There are few effective targeted strategies to reduce hepatic ischemia-reperfusion (IR) injury, a contributor to poor outcomes in liver transplantation recipients. …”
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430
Expression and Promoter Analysis of Six Heat Stress-Inducible Genes in Rice
Published 2013-01-01“…Six highly heat responsive genes were identified in rice by microarray data analysis. The qRT-PCR analysis confirmed that the expression of these six genes were highly heat inducible and moderately responded to salt stress, polyethylene glycol, and abscisic acid treatment, but little affected by cold treatment. …”
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431
Comprehensive analysis of intervention and control studies for the computational identification of dengue biomarker genes.
Published 2025-03-01“…Despite significant progress in understanding Dengue fever, effective prognosis and treatment remain elusive due to the complex clinical presentations and limitations in current diagnostic methods. …”
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432
Upregulated interleukin‐6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma
Published 2015-08-01“…Mechanisms of acquired resistance to the EGFR TKI erlotinib was investigated by developing erlotinib‐resistant HNSCC cell lines and comparing their gene expression profiles with their parental erlotinib‐sensitive HNSCC cell lines using microarray analyses and subsequent pathway and network analyses. …”
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433
Potential application of the bulk RNA sequencing in routine MPN clinics
Published 2025-04-01“…Additionally, data from the microarray datasets [GSE26049, GSE2191] were included in this study. …”
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434
Transcriptomic profile induced by calcitriol in CaSki human cervical cancer cell line.
Published 2025-01-01“…We examined the transcriptional changes induced by calcitriol in CaSki cells, a cervical cell line harboring multiple copies of HPV16, the primary causal agent of cervical cancer. Our microarray findings, revealed that calcitriol regulated over 1000 protein-coding genes, exhibiting a predominantly repressive effect on the CaSki cell transcriptome by suppressing twice as many genes as it induced. …”
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435
The novel long noncoding RNA linc00467 promotes cell survival but is down-regulated by N-Myc.
Published 2014-01-01“…Moreover, Affymetrix microarray analysis revealed that one of genes significantly up-regulated by linc00467 siRNA was the tumour suppressor gene DKK1. …”
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436
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Published 2013-01-01“…We used live-cell imaging and high content image analysis tools and identified JNJ-10198409 (J101) as an agent that induces mitotic arrest at prometaphase in GNS cells but not NS cells. Antibody microarrays and kinase profiling suggested that J101 responses are triggered by suppression of the active phosphorylated form of polo-like kinase 1 (Plk1) (phospho T210), with resultant spindle defects and arrest at prometaphase. …”
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437
A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data.
Published 2020-01-01“…We utilised available microarray gene-expression data for two phenotypes (starvation-sensitive and sterile) in Drosophila. …”
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438
Decrease in pneumococcal co-colonization following vaccination with the seven-valent pneumococcal conjugate vaccine.
Published 2012-01-01“…Microarray analysis confirmed the plyNCR-RFLP results. …”
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439
Amogel: a multi-omics classification framework using associative graph neural networks with prior knowledge for biomarker identification
Published 2025-03-01“…Abstract The advent of high-throughput sequencing technologies, such as DNA microarray and DNA sequencing, has enabled effective analysis of cancer subtypes and targeted treatment. …”
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440
A retrospective analysis of 6942 amniocentesis cases
Published 2025-08-01“…Among the single-method cases, Chromosomal Microarray Analysis (CMA) was the most frequently selected technique (14.18%). …”
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