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1021
Genetic Dissection of Learning and Memory in Mice
Published 2004-01-01“…Next, we briefly review more recently developed techniques, such as microarrays and RNA interference. In addition, we focus on gene-environment interactions and endophenotypes. …”
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1022
Comprehensive analysis of microRNA expression profile in malignant glioma tissues
Published 2015-08-01“…We investigated the global miRNA profile of malignant glioma tissues with miRNA microarrays, deep sequencing and meta‐analysis. We selected miRNAs that were most frequently deregulated in glioblastoma tissues, as well as in peritumoral areas, in comparison with normal human brain. …”
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1023
Gene Expression Analysis and Validation of a Novel Biomarker Signature for Early-Stage Lung Adenocarcinoma
Published 2025-05-01“…Using 22 pairs of LUAD and matched normal lung microarrays, 229 differentially expressed genes were identified. …”
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1024
Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes.
Published 2007-12-01“…Embryonic stem (ES) cells derived from the ICM of female mice have two active X chromosomes, one of which is inactivated as the cells differentiate in culture, providing a powerful model system to study the dynamics of X inactivation. Using microarrays to assay expression of X-linked genes in undifferentiated female and male mouse ES cells, we detect global up-regulation of expression (1.4- to 1.6-fold) from the active X chromosomes, relative to autosomes. …”
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1025
Accurate distinction of pathogenic from benign CNVs in mental retardation.
Published 2010-04-01“…Hundreds of CNVs can be detected in any individual genome using genomic microarrays or whole genome sequencing technology, but their phenotypic consequences are still poorly understood. …”
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1026
Re-evaluation of the relationship between PrPc expression and patient prognosis in primary esophageal squamous cell carcinoma and primary hepatocellular carcinoma
Published 2024-12-01“…We used flow cytometry to detect PrPc expression in ESCC and HCC cell lines. …”
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1027
Revealing new mouse epicardial cell markers through transcriptomics.
Published 2010-06-01“…<h4>Methodology</h4>Using laser capture microscopy, we isolated the epicardial layer from the adult murine heart before or after cardiac infarction in wildtype mice and mice expressing a transgenic IGF-1 propeptide (mIGF-1) that enhances cardiac repair, and analyzed the transcription profile using DNA microarrays.<h4>Principal findings</h4>Expression of epithelial genes such as basonuclin, dermokine, and glycoprotein M6A are highly enriched in the epicardial layer, which maintains expression of selected embryonic genes involved in epicardial development in mIGF-1 transgenic hearts. …”
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1028
Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Published 2015-01-01“…Selecting colorectal cancer (CRC) patients likely to respond to therapy remains a clinical challenge. …”
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1029
Nonlinear Quantitative Radiation Sensitivity Prediction Model Based on NCI-60 Cancer Cell Lines
Published 2014-01-01“…Important radiation therapy (RT) related genes were selected by significance analysis of microarrays (SAM). …”
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1030
Classification of gliomas based on genome-wide DNA methylation profiles and immunohistochemical analysis: a short study
Published 2024-12-01“…The formalin-fixed paraffin-embedded (FFPE) and freshly frozen (FF) samples were analyzed using Infinium Methylation-EPIC microarrays. The diagnosis was changed in two cases, and two other cases were classified as control tissue due to the low content of neoplastic cells in examined frozen samples. …”
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1031
Extended receptor repertoire of an adenovirus associated with human obesity.
Published 2025-01-01“…To date, this sialic acid variant has not been detected in humans, although it can be synthesized by various animal species, including a range of domestic and livestock animals. …”
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1032
Biomarker-Based Nomogram to Predict Neoadjuvant Chemotherapy Response in Muscle-Invasive Bladder Cancer
Published 2025-03-01“…Gene expression patterns were analysed in 34 samples from transurethral resection of the bladder (TURB) using Illumina microarrays. The expression levels of 45 selected differentially expressed genes between responders and non-responders to NAC were validated by quantitative PCR in an independent cohort of 157 patients. …”
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1033
Identification of components associated with thermal acclimation of photosystem II in Synechocystis sp. PCC6803.
Published 2010-05-01“…<h4>Methodology/findings</h4>We have analysed gene expression using whole-genome microarrays and monitored alterations in physiology during acclimation of PSII to elevated growth temperature in Synechocystis sp. …”
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1034
Proteomic and transcriptomic study of brain microvessels in neonatal and adult mice.
Published 2017-01-01“…In parallel, comparative transcript levels were obtained using RNA hybridization microarrays and enriched biological pathways were extracted from genes exhibiting at least a two-fold change in expression. …”
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1035
Distinct roles of non-canonical poly(A) polymerases in RNA metabolism.
Published 2009-07-01“…In conclusion, our results suggest that paralogous TRAMP complexes have distinct RNA selectivities with functional implications in RNA surveillance as well as other RNA-related processes. …”
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1036
Interleukin-13 receptor alpha 2 expression in tumor cells is associated with reduced disease-free survival in patients with luminal subtype invasive breast cancer
Published 2018-06-01“…Interleukin-13 receptor alpha 2 expressions were assessed by immunohistochemistry in tissue microarrays of 1283 invasive breast cancer samples, and associations between these expressions and clinicopathological variables and clinical outcomes were investigated. …”
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1037
Immunohistochemical TTF-1 and Napsin a Expression in Gastrointestinal Adenocarcinomas—Low Frequency but an Important Pitfall
Published 2025-06-01“…<b>Methods</b>: Buffered formalin-fixed paraffin-embedded tumor tissues from 854 patients with primary resected gastrointestinal and esophageal carcinomas were placed in tissue microarrays (TMAs) for investigation. Between two and six tumor cores were analyzed for each case. …”
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1038
The Response of Enterococcus faecalis V583 to Chloramphenicol Treatment
Published 2010-01-01“…Efflux of drug out of the cells may be one mechanism used by V583 to overcome the effect of chloramphenicol.…”
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1039
Comprehensive analysis of single-cell and bulk RNA sequencing data unveils antigen-presenting and processing fibroblasts and establishes a predictive model in gastric cancer
Published 2025-06-01“…The predictive model based on APPFRGs effectively predicts the prognosis and tumor immune status of GC.…”
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1040
Membranous Overexpression of Fibronectin Predicts Microvascular Invasion and Poor Survival Outcomes in Patients with Hepatocellular Carcinoma
Published 2025-03-01“…Methods: Immunohistochemical analysis of FN was conducted using tissue microarrays from 258 surgically resected HCCs and matched nontumorous liver tissues. …”
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