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Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression
Published 2009-10-01“…This confirms previous predictions from mathematical modeling of a global causal coordination between DNA replication origin activity and mRNA expression, and shows that mathematical modeling of DNA microarray data can be used to correctly predict previously unknown biological modes of regulation.…”
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Using effective subnetworks to predict selected properties of gene networks.
Published 2010-10-01“…Steady state measurements of these influence networks can be obtained from DNA microarray experiments. However, since they contain a large number of nodes, the computation of influence networks requires a prohibitively large set of microarray experiments. …”
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Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report
Published 2025-02-01“…High-resolution SNP microarray studies detected whole genome uniparental isodisomy. …”
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Identification of potential biomarkers and pathways related to major depressive disorder by integrated bioinformatic analysis and experimental validation
Published 2025-05-01“…Objective: To identify promising biomarkers for the pathogenesis of major depressive disorder (MDD). Methods: Microarray chips of MDD patients, including the GSE98793, GSE52790, and GSE39653 datasets, were obtained from the Gene Expression Omnibus database. …”
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Expression of long non-coding RNA in patients with non-IgA mesangial proliferative glomerulonephritis
Published 2015-01-01“…Objective To study differential expression profile of mRNA and long non-coding RNA(IncRNA) through microarray analysis between non-IgA mesangial proliferative glomerulonephritis(MsPGN) patients and the controls,and then explore the potential role of IncRNA in the pathogenesis of non-IgA MsPGN.Methods Through simple random sampling,4 patients with non-IgA MsPGN and 2 controls were selected as disease group and control group,respectively.Renal cortical tissues from two groups were collected.Total RNA was extracted,quantified and prepared to ds-cDNA through reverse transcription ds-cDNA was labeled with NimbleGen one-color DNA labeling kit and used for array hybridization.All experimental data were processed through GO analysis,Pathway analysis and the gene loci correlation analysis of mRNA and IncRNA.Some IncRNAs that were closely related to non-IgA MsPGN were screened out.Finally,part of the array results was detected by PCR to verify the reliability of array test Results By fold change filtering,4317 differentially expressed mRNAs and 3502 differentially expressed IncRNAs were screened out.Five IncRNAs were found to play potential roles in the pathogenesis of non-IgA MsPGN:AF1180924(close to coding gene FGG),AK092233(close to coding gene COL18A1),AK130579(close to coding gene CREBBP),AK023598(close to coding gene LEPR),and AK055915(close to coding gene CDC42EP3).These results provided an important basis for revealing the pathogenesis of non-IgA MsPGN.Conclusions Some IncRNAs can potentially regulate related genes and plays an important role in the pathogenesis and development of non-IgA MsPGN.…”
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Gene selection based on adaptive neighborhood-preserving multi-objective particle swarm optimization
Published 2025-05-01Subjects: “…Microarray gene selection…”
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Optimized T7 Amplification System for Microarray Analysis
Published 2001-10-01“…Glass cDNA microarray technologies offer a highly parallel approach for profiling expressed gene sequences in disease-relevant tissues. …”
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A two stage grading approach for feature selection and classification of microarray data using Pareto based feature ranking techniques: A case study
Published 2020-02-01“…High dimensional search space in microarray data with large number of genes and few dozen of samples increases the complexity of analysis of such databases. …”
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Microarray analysis of the effects of Acthar Gel versus methylprednisolone in a model of focal segmental glomerulosclerosis in female rats
Published 2025-04-01“…On Day 56, animals were sacrificed, and RNA samples of kidney cortex tissue were analyzed using microarrays. Compared with control, Acthar significantly decreased the expression of more genes related to inflammation, immune function, and fibrosis than MP. …”
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Genetic etiology and pregnancy outcomes of fetal hyperechoic kidneys: a retrospective analysis
Published 2025-08-01“…Chromosome karyotyping and chromosomal microarray analysis (CMA) were performed on fetuses displaying this phenotype on prenatal ultrasound. …”
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Analysis of a Series of 26 Cases With Prenatal Skeletal Dysplasia via Multiplatform Genetic Detection
Published 2025-01-01“…Materials and Methods In this study, we recruited 26 cases of SD and analyzed them with a designed sequential genetic detection. Chromosome karyotyping, microarray analysis (CMA), and whole exome sequencing (WES) techniques are performed as needed. …”
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Microarray-Based Cancer Diagnosis with Artificial Neural Networks
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Listen to genes: dealing with microarray data in the frequency domain.
Published 2009-01-01“…<h4>Background</h4>We present a novel and systematic approach to analyze temporal microarray data. The approach includes normalization, clustering and network analysis of genes.…”
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A Sensitive and Fast microRNA Detection Platform Based on CRlSPR-Cas12a Coupled with Hybridization Chain Reaction and Photonic Crystal Microarray
Published 2025-04-01“…The sensitive and fast detection of miRNAs is critical for diagnosis and prognosis. …”
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Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities
Published 2025-06-01“…Chromosome microarray analysis detected abnormalities in 6.58% (5/76) of the isolated cardiac abnormalities group and 27.27% (6/22) in the group with combined abnormalities, showing a significant statistical difference (P < 0.05). …”
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A universal DNA microarray for rapid fish species authentication
Published 2025-06-01“…DNA microarrays are now used in fields such as gene expression analysis, pathogen/virus detection and identification of biomarkers. …”
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