-
721
Thyroid hormone signalling genes are regulated by photoperiod in the hypothalamus of F344 rats.
Published 2011-01-01“…Surprisingly, large changes in hypothalamic thyroid hormone levels or TRH expression were not detected. Expression of NPY and GALP, two genes known to regulate GHRH, were also changed by photoperiod. …”
Get full text
Article -
722
The Construction of ceRNA Regulatory Network Unraveled Prognostic Biomarkers and Repositioned Drug Candidates for the Management of Pancreatic Ductal Adenocarcinoma
Published 2025-06-01“…The mRNA, miRNA, and circRNA expression profiles of PDAC were obtained from nine microarray datasets. Differentially expressed genes (DEGs), microRNAs (DEmiRNAs), and circular RNAs (DEcircRNAs) were identified. …”
Get full text
Article -
723
Screening of key genes related to angiogenesis in rosacea based on bioinformatics analysis
Published 2025-04-01“…Methods The gene microarray dataset GSE65914 was retrieved from the Gene Expression Omnibus (GEO) repository. …”
Get full text
Article -
724
Quantitative Expression of SFN, lncRNA CCDC18-AS1, and lncRNA LINC01343 in Human Breast Cancer as the Regulator Biomarkers in a Novel ceRNA Network: Based on Bioinformatics and Exp...
Published 2022-01-01“…In this study, after performing GSEA and microarray analysis on the GSE71053 dataset, a new ceRNA network of CCDC18-AS1, LINC01343, hsa-miR4462, and SFN in BC was detected by bioinformatics analysis. …”
Get full text
Article -
725
Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke
Published 2025-04-01“…Three machine learning algorithms were employed to detect biomarkers from the core shared genes, and the diagnostic value of the hub genes was evaluated by establishing a predictive nomogram. …”
Get full text
Article -
726
Cyr61 Mediates Angiotensin II-Induced Podocyte Apoptosis via the Upregulation of TXNIP
Published 2023-01-01“…Gene microarray was used to analyze the expression of mRNAs after treatment with Ang II. …”
Get full text
Article -
727
DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals
Published 2017-03-01“…Here, we performed microarray-based DNA methylation and gene expression profiling of peripheral white blood cells obtained from six young, obese individuals and six healthy controls. …”
Get full text
Article -
728
Metastatic melanoma: An integrated analysis to identify critical regulators associated with prognosis, pathogenesis and targeted therapies.
Published 2025-01-01“…Subsequently, the hub genes were selected using GEPIA. Survival analysis was performed using the TCGA. …”
Get full text
Article -
729
Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis.
Published 2010-12-01“…Confirmation of the expression patterns of select genes was obtained by qRT-PCR. Using significance analysis of microarrays with a 5% false discovery rate, 71 and 60 non-redundant transcripts were identified to be ≥2-fold up-regulated and ≤0.6-fold down-regulated, respectively, in sheared chondrocytes. …”
Get full text
Article -
730
Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi.
Published 2016-01-01“…The transcriptome microarray data, validated by quantitative Real-Time PCR, was also confirmed by immunoblotting and customized Enzyme Linked Immunosorbent Assays (ELISA) array showing significant increases in the protein expression levels of fibrogenic EGR1, SNAI1 and IL 6. …”
Get full text
Article -
731
Stroma regulates increased epithelial lateral cell adhesion in 3D culture: a role for actin/cadherin dynamics.
Published 2011-04-01“…The upregulated growth factors TGFβ2, CXCL12 and FGF10 were selected for further analysis because of previous associations with morphology. …”
Get full text
Article -
732
Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome.
Published 2011-01-01“…Androgens drive the onset and progression of prostate cancer (PCa) by modulating androgen receptor (AR) transcriptional activity. Although several microarray-based studies have identified androgen-regulated genes, here we identify in-parallel global androgen-dependent changes in both gene and alternative mRNA isoform expression by exon-level analyses of the LNCaP transcriptome. …”
Get full text
Article -
733
Fetal medicine and current practice of prenatal screening
Published 2023-01-01“…The fetal sample is used for various genetic tests, such as chromosome microarray analysis (CMA), targeted clinical exome sequencing (CES), or whole exome sequencing (WES) depending upon the abnormality noted or the suspected genetic condition. …”
Get full text
Article -
734
Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis
Published 2024-10-01“…Methods Five DCM-related microarray datasets were downloaded from the Gene Expression Omnibus (GEO). …”
Get full text
Article -
735
Antibiotic resistance in agroecosystem: Progress and challenges
Published 2017-11-01“…Both culture-dependent and culture-independent technologies, including metagenomic, microarray and high-throughput quantitative polymerase chain reaction have been utilized in the characterization of ARGs in agroecosystem, and each has its strength and weakness. …”
Get full text
Article -
736
Interaction of Wnt Signaling with BMP/Smad Signaling during the Transition from Cell Proliferation to Myogenic Differentiation in Mouse Myoblast-Derived Cells
Published 2013-01-01“…The BMP antagonist noggin effectively stimulated muscle differentiation through binding to endogenous BMPs, and the effect of noggin was enhanced by the presence of Wnt3a and Wnt4. …”
Get full text
Article -
737
Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.
Published 2013-01-01“…Of note, other IL-12 family members (IL-12, IL-23 and IL-35) had no effect on HIV-1 replication. Microarray studies of IL-27 treated DCs showed no up-regulation of Type I (IFN) gene expression. …”
Get full text
Article -
738
Anti-Obesity Properties of <i>Boesenbergia rotunda</i> Rhizome Extract: Regulation of Inflammation, Lipid Metabolism, and Insulin Signaling in <i>ob/ob</i> Mice
Published 2025-01-01“…Next, we investigated the anti-obesity effects of BR extract in <i>ob/ob</i> mice, a type 2 diabetes mellitus model. …”
Get full text
Article -
739
γ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway.
Published 2014-01-01“…We found a protective effect of γ-synuclein antibody resulting in an increased viability (up to 15%) and decreased reactive oxygen species levels (up to -12%) of glutamate and oxidative stressed RGC-5. …”
Get full text
Article -
740
16S Ribosomal Ribonucleic Acid Gene Polymerase Chain Reaction in the Diagnosis of Bloodstream Infections: A Systematic Review and Meta-Analysis.
Published 2015-01-01“…Further prospective studies are needed to assess the diagnostic value of PCR amplification and DNA microarray hybridization of 16S rRNA gene in the future.…”
Get full text
Article