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701
Extracellular vesicle-packaged miR-4253 secreted by cancer-associated fibroblasts facilitates cell proliferation in gastric cancer by inducing macrophage M2 polarization
Published 2024-12-01“…Here, we investigated the effect of CAF-EVs on macrophage polarization in GC and the underlying mechanisms. …”
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702
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction.
Published 2009-12-01“…We investigated the transcriptional changes that occur during endothelial differentiation of hESCs using whole genome microarray, and compared to human umbilical vein endothelial cells (HUVECs). …”
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703
Investigational Management for a Positive NIPT Result - Case Report
Published 2024-06-01“…Following genetic consultation, further investigations were conducted to stratify the fetal risk of inheriting the microdeletion syndrome. As a result, microarray CGH cytoarray from amniotic fluid was performed, and no 22q11.2 deletion was detected. …”
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704
Polymorphisms in the mitochondrial DNA control region and frailty in older adults.
Published 2010-06-01“…At baseline, frailty was identified as the presence of three or more of five indicators (weakness, slowness, shrinking, low physical activity, and exhaustion). mtDNA variation was assessed in a pilot study, including 315 individuals selected as extremes of the frailty phenotype, using an oligonucleotide sequencing microarray based on the Revised Cambridge Reference Sequence. …”
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705
Exploring Flexible Penalization of Bayesian Survival Analysis Using Beta Process Prior for Baseline Hazard
Published 2025-01-01“…Moreover, in microarray research, it is common to identify groupings of genes involved in the same biological pathways. …”
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706
A comprehensive review of diagnostic approaches for hepatitis D
Published 2025-05-01“…Established techniques like chemiluminescence immunoassay, quantitative microarray antibody capture, and lateral flow assays are being improved. …”
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707
Prenatal diagnosis of imprinted associated chromosome abnormalities identified by noninvasive prenatal testing (NIPT)
Published 2025-04-01“…Abstract To explore the clinical value of noninvasive prenatal testing (NIPT) combined with chromosomal microarray analysis (CMA)/copy number variation sequencing (CNV-seq), methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA), and fluorescence in situ hybridization (FISH) in the early screening of imprinted chromosome abnormalities. …”
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708
Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor.
Published 2017-01-01“…A number of single nucleotide variations (SNVs)/mutations were detected in OVDM1 and the metastatic tumor samples. …”
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709
The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription
Published 2016-01-01“…MFISH and CGH revealed distinct instability of chromosome structure in RKO. Gene expression microarray of RKO versus 7 colon cancer lines (with active Wnt signaling) and 3 normal specimens revealed 611 differentially expressed genes. …”
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710
ZNF37A downregulation promotes TNFRSF6B expression and leads to therapeutic resistance to concurrent chemoradiotherapy in rectal cancer patients
Published 2025-01-01“…The identification a signature comprising a group of genes as markers of cancer response to chemoradiotherapy would be more appropriate and effective for predicting chemoradiotherapy efficacy. …”
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711
Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome
Published 2016-01-01“…To assess the expression of autoantibodies in the blood plasma, we used a protein microarray, which allows for simultaneous determination of 9000 proteins per sample. …”
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712
Copy Number Variation of Immune-Related Genes and Their Association with Iodine in Adults with Autoimmune Thyroid Diseases
Published 2018-01-01“…Blood samples from 15 patients with AITD and 15 controls were assessed by chromosome microarray to identify candidate genes. The copy number of candidate genes and urinary iodine level was determined in adults from areas of different iodine statuses including 158 patients and 181 controls. …”
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713
Mechanisms of ag85a/b DNA vaccine conferred immunotherapy and recovery from Mycobacterium tuberculosis‐induced injury
Published 2023-05-01“…The gene expression profiles were analyzed using gene microarray technology to obtain differentially expressed (DE) genes. …”
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714
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma
Published 2025-08-01“…Inhibition or knockdown of USP7 reduces MGMT levels, as well as those of XPC, ALKBH2, and ALKBH3, impairs DNA repair capacity, and sensitizes GBM cells to TMZ, enabling effective treatment with reduced TMZ dosages. Clinically, tissue microarray analyses reveal that USP7 and MGMT co-overexpression in GBM correlates with poor patient survival. …”
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715
Human umbilical vein endothelial cell miRNA secretome highlights endothelial origin of serum miRNAs
Published 2025-07-01“…Our results also demonstrate that the microarray technology has great use in precision microRNA biomarker discovery using simple models, which should be utilised for further mapping of cell-type specific healthy signatures to further refine blood-based diagnostics.…”
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716
Molecular Signatures of Recurrent Hepatocellular Carcinoma Secondary to Hepatitis C Virus following Liver Transplantation
Published 2013-01-01“…Microarray analysis containing more than 29,000 known genes was performed on formalin-fixed-paraffin-embedded (FFPE) liver tissue from explanted livers. …”
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717
Identification and Characterization of Cyprinid Herpesvirus-3 (CyHV-3) Encoded MicroRNAs.
Published 2015-01-01“…MiRNAs from the two confirmed pre-miRNAs were also detected in gill tissue from CyHV-3-infected carp. …”
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718
The impact of MITF expression on tumor-infiltrating lymphocytes in melanoma: Insights into immune microenvironment dynamics
Published 2025-02-01“…Archival formalin-fixed, paraffin-embedded tissue samples from 81 primary melanoma patients were analyzed via tissue microarray immunohistochemistry to assess MITF protein levels. …”
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719
Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules.
Published 2014-01-01“…We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based) and humans (mRNA-sequencing-based) and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. …”
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720
The Novel Action of miR-193b-3p/CDK1 Signaling in HCC Proliferation and Migration: A Study Based on Bioinformatic Analysis and Experimental Investigation
Published 2022-01-01“…A growing number of novel targets underlying HCC pathophysiology have been detected using microarray high throughput screening platforms. …”
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