Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogen-activated protein kinase pathway. by Yuan-Ching Chang, Yi-Chiung Hsu, Chien-Liang Liu, Shih-Yuan Huang, Meng-Chun Hu, Shih-Ping Cheng

“…Recent evidence suggests that local anesthetics have a broad spectrum of effects including inhibition of cell proliferation and induction of apoptosis in neuronal and other types of cells. …”
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Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling. by Deborah C Mash, Jarlath ffrench-Mullen, Nikhil Adi, Yujing Qin, Andrew Buck, John Pablo

“…The chronic effects of cocaine abuse on brain structure and function are blamed for the inability of most addicts to remain abstinent. …”
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M2-like macrophage-derived exosomes inhibit osteoclastogenesis via releasing miR-1227-5p by Shan Chen, Jian Liu, Lilei Zhu

“…The molecular mechanism was evaluated using microarray analysis, RT-qPCR, dual-luciferase reporter analysis, and RNA pull-down assay. …”
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Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systems. by Takuto Nosaka, Tatsushi Naito, Yu Akazawa, Kazuto Takahashi, Hidetaka Matsuda, Masahiro Ohtani, Tsutomu Nishizawa, Hiroaki Okamoto, Yasunari Nakamoto

“…RNA microarray was performed using HBV-infected PXB cells with STAT1 knockdown. …”
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Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study by Li Gao, Shi-Bai Yan, Fang-Cheng Jiang, Zhi-Guang Huang, Dong-Ming Li, Yu-Lu Tang, Jia-Yuan Luo, Gang Chen, Dan-Ming Wei

“…We explored the expression pattern and clinicopathological significance of ZIC2 in oral cancer through performing in-house tissue microarray and integrated analysis global RNA-seq and microarrays containing large samples. …”
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Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation. by Lisa Y Pang, Emma L Gatenby, Ayako Kamida, Bruce A Whitelaw, Ted R Hupp, David J Argyle

“…We found that COX-2 inhibition had no effect on CSC growth, or resistance to chemotherapy. …”
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Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant. by Rhea N Coler, Sylvie Bertholet, Magdalini Moutaftsi, Jeff A Guderian, Hillarie Plessner Windish, Susan L Baldwin, Elsa M Laughlin, Malcolm S Duthie, Christopher B Fox, Darrick Carter, Martin Friede, Thomas S Vedvick, Steven G Reed

“…We report here on the characterization of a synthetic hexaacylated lipid A derivative, denoted as glucopyranosyl lipid adjuvant (GLA). We assessed the effects of GLA on murine and human dendritic cells (DC) by combining microarray, mRNA and protein multiplex assays and flow cytometry analyses. …”
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A plant diterpene counteracts juvenile hormone-mediated gene regulation during Drosophila melanogaster larval development. by Sang Woon Shin, Jun Hyoung Jeon, Seon Ah Jeong, Ji-Ae Kim, Doo-Sang Park, Yunhee Shin, Hyun-Woo Oh

“…Gene ontology analysis also suggested that some of the genes activated-by-JHA/repressed-by-JHD play roles in spermatogenesis. Affymetrix microarray-based analysis indicated that the expression of genes activated-by-JHA/repressed-by-JHD was testis-specific. …”
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Bioinformatic identification of Single Nucleotide Polymorphisms (SNPs) in keratin-associated protein genes in alpacas (Vicugna pacos) by Deyanira Figueroa, Manuel More, Gustavo Gutiérrez, F. Abel Ponce de León

“…Of these, 35 SNPs were included in the 76K alpaca SNP microarray and 32 SNPs were confirmed in a population of 936 alpacas.…”
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Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks by James N. Warnock, Bindu Nanduri, Carol A. Pregonero Gamez, Juliet Tang, Daniel Koback, William M. Muir, Shane C. Burgess

“…Linear, two-cycle amplification of total RNA, followed by microarray was performed for transcriptome analysis (with qRT-PCR validation). …”
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Cytogenomic characterization of mosaic X-ring chromosomes in seventeen patients with Turner syndrome (TS)-42 years of experience at a single-site institution by Anita Madison, Carolyn Applegate, Victoria Stinnett, Diego Marrero Miranda, Chantal Cross, Kamaria Cayton Vaught, Ying S. Zou, Jaclyn B. Murry

“…Current guidelines recommend karyotype as the first-line test rather than SNP microarray analysis when aneuploidy is suspected. Conventional cytogenetics is still necessary to understand structural abnormalities, provide genomic context, and detect low-level mosaicism. …”
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Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression by Itai Yanai, L Ryan Baugh, Jessica J Smith, Casey Roehrig, Shai S Shen‐Orr, Julia M Claggett, Andrew A Hill, Donna K Slonim, Craig P Hunter

“…We used RNAi and time series, whole‐genome microarray analyses to systematically perturb and characterize components of a Caenorhabditis elegans lineage‐specific transcriptional regulatory network. …”
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Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology by Brian Cox, Max Kotlyar, Andreas I Evangelou, Vladimir Ignatchenko, Alex Ignatchenko, Kathie Whiteley, Igor Jurisica, S Lee Adamson, Janet Rossant, Thomas Kislinger

“…We collected protein and mRNA expression data through shot‐gun proteomics and microarray expression analysis of the highly vascular exchange region, microdissected from the human and mouse near‐term placenta. …”
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A very rare case of a newborn with tetrasomy 9p and literature review by Merve Süleyman, Sümeyra Oğuz, Gözdem Kaykı, Hasan Tolga Çelik, Pelin Özlem Şimsek-Kiper, Gülen Eda Utine, Şule Yiğit

“…Microarray analysis revealed 38,584 kb tetrasomic region at 9p24.3p13.1. …”
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Informative value of rapid microbiological diagnostic tests and experience in studying a procalcitonin assay in the evaluation of the activity of a mycobacterial population in chil... by L. V. Panova, E. S. Ovsyankina, M. M. Averbakh, F. A. Poluektova, O. A. Piskunova

“…Drug resistance in MBT was determined by a microarray test in only 16 (23.5%) out of 68 patients for lack or paucity of DNA in the diagnostic material. …”
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Association between a specific monocyte subset and heart failure with preserved ejection fraction in patients with uremia by Xinrui Wang, Minghui Song, Lu Ma, Yang Yang

“…Conclusions: Specific gene detections can be an important early warning indicator and guide physicians in evaluating the risk of HFpEF in ESRD.…”
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TLR3 Plays Significant Roles against HBV-Associated HCC by Xiao-lan Chen, Yu-yin Xu, Li Chen, Gui-lan Wang, Yin Shen

“…The apoptosis of tumor cells was also detected by TUNEL stain. Correlations between TLR3 expression and HBV infection, interstitial immunoreactive cells, and cells apoptosis in HCC were investigated. …”
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A long non-coding RNA lncRNA-PE promotes invasion and epithelial–mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway by Yuan Shen, Shanshan Liu, Hanyu Yuan, Xiaomin Ying, Hanjiang Fu, Xiaofei Zheng

“…However, the detailed mechanisms underlying their activities are not fully understood. Using microarray technology, a number of long non-coding RNAs were previously identified to be aberrantly expressed in hepatocellular carcinoma. …”
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iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models. by Bahadir Ozdemir, Wael Abd-Almageed, Stephanie Roessler, Xin Wei Wang

“…We defined a method to transform microarray data into graph representation that encodes miRNA and gene expression levels and the interactions between them as well. …”
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Immortalized Human Schwann Cell Lines Derived From Tumors of Schwannomatosis Patients. by Kimberly Laskie Ostrow, Katelyn Donaldson, Jaishri Blakeley, Allan Belzberg, Ahmet Hoke

“…Cell morphology was retained following multiple passaging and freeze/ thaw cycles. Gene expression microarray analysis was used to compare the cell lines with their respective parent tumors. …”
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