Shannon entropy approach reveals relevant genes in Alzheimer's disease. by Alfonso Monaco, Nicola Amoroso, Loredana Bellantuono, Eufemia Lella, Angela Lombardi, Anna Monda, Andrea Tateo, Roberto Bellotti, Sabina Tangaro

“…Since complex diseases are often the result of combinations of gene interactions, microarray data and gene co-expression analysis can provide tools for addressing complexity. …”
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SLEPR: a sample-level enrichment-based pathway ranking method -- seeking biological themes through pathway-level consistency. by Ming Yi, Robert M Stephens

“…Analysis of microarray and other high throughput data often involves identification of genes consistently up or down-regulated across samples as the first step in extraction of biological meaning. …”
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An enhanced single base extension technique for the analysis of complex viral populations. by Dale R Webster, Armin G Hekele, Adam S Lauring, Kael F Fischer, Hao Li, Raul Andino, Joseph L DeRisi

“…This single base extension (SBE) based microarray platform was designed and optimized using poliovirus as the target genotype, but can be easily adapted to assay populations derived from any organism. …”
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HIF-1 inhibition reverses opacity in a rat model of galactose-induced cataract. by Masaru Takashima, Masaya Nagaya, Yoshihiro Takamura, Masaru Inatani, Masaya Oki

“…The detailed mechanism of cataract development has not been characterized, and effective drug therapies remain unavailable. Here, we investigated the effects of Hypoxia-inducible factor 1 (HIF-1) inhibitors using an ex vivo model, in which rat lenses were cultured in galactose-containing medium to induce opacity formation. …”
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Discovering structural cis‐regulatory elements by modeling the behaviors of mRNAs by Barrett C Foat, Gary D Stormo

“…We applied our structural cis‐regulatory element detector (StructRED) to microarray and mRNA sequence data from Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens. …”
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Study on the mechanisms and functions of lncRNAs in regulating carboplatin resistance in ovarian cancer cells by HONG Yi, CHEN Cuilan, YIN Fuqiang, LIU Xia

“…Based on expression profiling microarrays and RT-qPCR validation, lncRNA DAPK1-IT1, which was significantly down-regulated by more than 4-fold in both two carboplatin-resistant cell lines, was selected for functional verification. …”
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Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis by Gaoyan Tang, Xuelei Cao, Jiaqi Chen, Fu Hui, Na Xu, Yiqing Jiang, Hongmin Lu, Haifeng Xiao, Xiuming Liang, Mingzhe Ma, Yu Qian, Dongli Liu, Zhenlu Wang, Shuzhen Liu, Guohua Yu, Lei Sun

“…Furthermore, immunohistochemical (IHC) analysis of an NSCLC tissue microarray confirmed a strong positive correlation between p-p38 and NOXA expression. …”
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Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells. by Swojani Shrestha, Sandeep Singhal, Donald A Sens, Seema Somji, Bethany A Davis, Rachel Guyer, Spencer Breen, Matthew Kalonick, Scott H Garrett

“…The results validated the microarray analysis, which showed a significant decrease in the mRNA as well as protein expression of the selected genes as the concentration of glucose increased. …”
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Prediction of gene expression in embryonic structures of Drosophila melanogaster. by Anastasia A Samsonova, Mahesan Niranjan, Steven Russell, Alvis Brazma

“…The use of high-throughput approaches, such as large-scale in situ hybridisation and genome-wide expression profiling via DNA microarrays, is beginning to provide insights into the complexities of development. …”
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Identification of MEG3 and MAPK3 as potential therapeutic targets for osteoarthritis through multiomics integration and machine learning by Bing Ma, Xiaoru Wang, Chengfei Xu, Zelin Xu, Fei Zhang, Wendan Cheng

“…Subsequently, differential expression analysis and WGCNA were applied to synovial tissue microarray datasets obtained from the GEO database. …”
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Genetic Analysis of 17q Terminal Partial Trisomy by Huiling Zheng, Lin Zheng, Zhi Huang, Guangping Li, Daili Tang, Xue Yang, Tian Tian

“…We performed G‐banding karyotype and chromosomal microarray analyses. The child in Family 1 had a 31.3 Mb mosaic duplication on chromosome 17. …”
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Clinical experience of genome-wide non-invasive prenatal testing as a first-tier screening test in a cohort of 59,771 pregnancies. by Jianxin Zhen, Liting Zhang, Huilin Wang, Xi Chen, Weihong Wang, Lili Li, Quanfu Zhang

“…Here, we evaluated the clinical performance of GW-NIPT as a first-tier screening test for detecting fetal aneuploidy and copy number variation (CNV).…”
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Homozygous Microdeletion Involving Exon 1 of ERCC8 and NDUFAF2 With Uniparental Isodisomy of Chromosome 5 by Kaori Yamoto, Kosuke Yamada, Kenji Shimizu, Sachiko Miyamoto, Mitsuko Nakashima, Hirotomo Saitsu

“…Methods We performed chromosomal microarray analysis, exome sequencing (ES), and RNA sequencing (RNA‐seq) using the patient's urine‐derived cells on a patient with growth retardation and multiple congenital anomalies. …”
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Molecular profiles of HCV cirrhotic tissues derived in a panel of markers with clinical utility for hepatocellular carcinoma surveillance. by Ricardo C Gehrau, Kellie J Archer, Valeria R Mas, Daniel G Maluf

“…<h4>Background</h4>Early hepatocellular carcinoma (HCC) detection is difficult because low accuracy of surveillance tests. …”
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D-Mannose Inhibits Adipogenic Differentiation of Adipose Tissue-Derived Stem Cells via the miR669b/MAPK Pathway by Yitong Liu, Lijia Guo, Lei Hu, Chen Xie, Jingfei Fu, Yiyang Jiang, Nannan Han, Lu Jia, Yi Liu

“…To further explore the mechanisms, microarray analysis was performed to detect the differences between glucose-treated ADSCs (G-ADSCs) and D-mannose-treated ADSCs (M-ADSCs) in the gene expression level. …”
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Comparison of eleven methods for genomic DNA extraction suitable for large-scale whole-genome genotyping and long-term DNA banking using blood samples. by Androniki Psifidi, Chrysostomos I Dovas, Georgios Bramis, Thomai Lazou, Claire L Russel, Georgios Arsenos, Georgios Banos

“…Over the recent years, next generation sequencing and microarray technologies have revolutionized scientific research with their applications to high-throughput analysis of biological systems. …”
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Transcriptional profile of muscle following acute induction of symptoms in a mouse model of Kennedy's disease/spinobulbar muscular atrophy. by Katherine Halievski, Kaiguo Mo, J Timothy Westwood, Douglas A Monks

“…We previously reported a microarray study of genes differentially expressed in muscle of three genetically unique mouse models of KD/SBMA but were unable to detect those which are androgen-dependent or are associated with onset of symptoms.…”
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MicroRNA profiling in human colon cancer cells during 5-fluorouracil-induced autophagy. by Ni Hou, Jia Han, Jie Li, Yingxun Liu, Yannan Qin, Lei Ni, Tusheng Song, Chen Huang

“…The physiological importance of the miRNA-autophagy interconnection is only beginning to be elucidated. MiRNA microarray technology facilitates analysis of global miRNA expression in certain situations. …”
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An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: functional, metabolic, and differential network analysis. by Sriram Devanathan, Timothy Whitehead, George G Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S Korach, Brian N Finck, Kooresh I Shoghi

“…Estrogen exerts diverse biological effects in multiple tissues in both animals and humans. …”
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Psicoterapia e neuroscienze: il modello strategico ad orientamento neuroscientifico e il metodo mente - corpo by 1 Mauro Cozzolino, 2 Giovanna Celia

“…In this paper we illustrate an innovative and effective model called Neuroscientific Strategic Psychotherapy. …”
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