-
441
Acetylation suppresses breast cancer progression by sustaining CLYBL stability
Published 2025-04-01“…Methods CLYBL expression patterns in breast cancer were assessed using a breast cancer tissue microarray, immunohistochemistry, and publicly available datasets. …”
Get full text
Article -
442
Modulation of homologous recombination gene activity in breast tumor cells in an <i>in vitro</i> model
Published 2024-06-01“…To assess the presence of chromosomal aberrations, microarray analysis was performed on DNA chips.Results. …”
Get full text
Article -
443
Cystatin B Promotes the Proliferation, Migration, and Invasion of Intrahepatic Cholangiocarcinoma
Published 2025-01-01“…The clinical significance of CSTB was analyzed through immunohistochemical staining of a tissue microarray. Subsequently, the biological effects of CSTB overexpression or knockdown on iCCA cells were evaluated in vitro and in vivo. …”
Get full text
Article -
444
Caveolin-1 inhibits the proliferation and invasion of lung adenocarcinoma via EGFR degradation
Published 2025-07-01“…The expressions of CAV1 and EGFR in LUAD tissues and adjacent tissues were detected by Western blotting, immunohistochemistry and microarray technology. …”
Get full text
Article -
445
Molecular mechanism and biological pathway of high-expressed RAD51 in regulating cell adhesion and potentially affecting oral squamous cell carcinoma
Published 2025-07-01“…Methods Bulk RNA (RNA-seq and microarray), immunohistochemistry (IHC), and single-cell sequencing (scRNA-seq) were used to assess RAD51 expression and its clinical relevance in OSCC. …”
Get full text
Article -
446
IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming
Published 2025-04-01“…Abstract Ovarian cancer (OC) is often detected at an advanced stage and has a high recurrence rate after surgery or chemotherapy. …”
Get full text
Article -
447
Sequential prenatal diagnosis of fetal skeletal dysplasia: A cohort study
Published 2025-05-01“…Abstract Introduction Genetic factors are considered to be the main factors leading to fetal skeletal dysplasia (SD), and chromosomal microarray analysis (CMA) has been used clinically for the detection of SD fetuses. …”
Get full text
Article -
448
Nanopore-based random genomic sampling for intraoperative molecular diagnosis
Published 2025-01-01“…Results In our retrospective cohort of 26 malignant brain tumors, iSCORED demonstrated 100% concordance in CNV detection, including chromosomal alterations and oncogene amplifications, when compared to clinically validated assays such as Next-Generation Sequencing and Chromosomal Microarray. …”
Get full text
Article -
449
Identification and Validation of a Potential Marker of Tissue Quality Using Gene Expression Analysis of Human Colorectal Tissue.
Published 2015-01-01“…Normal colorectal tissue and CRC tissue was analyzed using microarray and quantitative real-time PCR (qPCR). Comparing changes in gene expression between pre- and post-surgical tissue using microarray analysis identified a list of potential tissue quality biomarkers and this list was validated using qPCR. …”
Get full text
Article -
450
Renal tissue thawed for 30 minutes is still suitable for gene expression analysis.
Published 2014-01-01“…We aim to evaluate the effects of thawing at room temperature for different time periods on gene expression analysis. …”
Get full text
Article -
451
Long read whole genome sequencing-based discovery of structural variants and their role in aetiology of non-syndromic autism spectrum disorder in India
Published 2025-08-01“…Short read sequencing (SRS) and chromosomal microarray (CMA) are unable to resolve these SVs due to their inherent technological limitations. …”
Get full text
Article -
452
AgileMultiIdeogram: Rapid Identification and Visualization of Autozygous Regions Using Illumina Short-Read Sequencing Data
Published 2025-06-01“…A well-established and effective way of identifying these “autozygous” genomic regions has been to search for runs of homozygous genotypes in microarray SNP data. …”
Get full text
Article -
453
Over-expression of either MECP2_e1 or MECP2_e2 in neuronally differentiated cells results in different patterns of gene expression.
Published 2014-01-01“…DOCK8 was shown via microarray and qRT-PCR to be upregulated in both SK-N-SH cells and mouse fibroblasts. …”
Get full text
Article -
454
Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature
Published 2025-01-01“…Here, we use liquid chromatography–mass spectrometry and gene expression microarray to profile integrated intratumour metabolic heterogeneity, as a direct functional readout of adaptive responses of subclones to the tumour microenvironment. …”
Get full text
Article -
455
The absolute number of T lymphocyte subsets is beneficial for differential diagnosis of myelodysplastic syndrome with pure red cell aplastic anemia: a case report and review of the...
Published 2025-04-01“…The result of the morphological examination of bone marrow, whole-genome microarray, and bone marrow biopsy all supported the diagnosis of MDS at the first clinical diagnosis. …”
Get full text
Article -
456
Hypoxia-Induced miR-210 Promotes Endothelial Cell Permeability and Angiogenesis via Exosomes in Pancreatic Ductal Adenocarcinoma
Published 2022-01-01“…The aim of this article was to identify and investigate abnormally expressed miRNAs in PDAC exosomes in vivo and in vitro. Methods. Microarray studies were used to detect aberrantly expressed miRNAs in PDAC exosomes, and miR-210 expression in cells or exosomes was further analyzed by qRT-PCR. …”
Get full text
Article -
457
Characterization of a MERS-related betacoronavirus in Danish brown long-eared bats (Plecotus auritus)
Published 2025-08-01“…Positive samples underwent ORF1b sequencing, microarray analysis and Illumina MiSeq sequencing, followed by metagenomic assembly of full-length genomes. …”
Get full text
Article -
458
Berberine Improves Inflammatory Responses of Diabetes Mellitus in Zucker Diabetic Fatty Rats and Insulin-Resistant HepG2 Cells through the PPM1B Pathway
Published 2020-01-01“…Microarray analysis of liver tissues was performed, and differentially expressed gene (DEG) levels were examined by quantitative real-time PCR (qPCR) and Western blot. …”
Get full text
Article -
459
Directional genomic hybridization (dGH™) identifies small inverted duplications in situ
Published 2025-06-01“…This technique may be used to identify the presence of small inversions within regions presenting a copy number gain as detected by chromosome microarray. Distinguishing small inverted duplications from direct duplications may have an impact on topologically associating domains (TADs) and, thus, on clinical outcome.…”
Get full text
Article -
460
Identification of Potential Biomarkers of Septic Shock Based on Pathway and Transcriptome Analyses of Immune-Related Genes
Published 2023-01-01“…Our aim was to explore potential biomarkers for SS by pathway and transcriptional analyses of immune-related genes to improve early detection. GSE57065 and GSE95233 microarray data were used to screen differentially expressed genes (DEGs) in SS. …”
Get full text
Article