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A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma.
Published 2013-01-01“…This shows superior survival separation for assigned Activated B-cell (ABC) and Germinal Center B-cell (GCB) DLBCL classes relative to a range of other classifiers. DAC is effective on data derived from multiple microarray platforms and formalin fixed paraffin embedded samples and is parsimonious, using 20 classifier genes. …”
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162
Using machine learning to discover DNA metabolism biomarkers that direct prostate cancer treatment
Published 2025-07-01Get full text
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163
Evaluation of Genomic Variants in Non-syndromic Congenital Heart Disease in Turkish Pediatric Group
Published 2025-07-01“…Results: In microarray analysis, 9 novel copy-number variations (CNVs) that were not reported in population databases, and included OMIM genes were detected in 1.5% (6/40) of the patients. …”
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164
GPC3 as a potential diagnostic and prognostic marker for lung adenocarcinoma
Published 2024-12-01“…Four gene expression profiles were downloaded from GEO and merged into a training cohort, and those genes that were differentially expressed between LUAD and normal samples were selected. We performed LASSO regression, SVM-RFE, and ROC curve analyses, and external validations were conducted using the GSE115002 dataset, TCGA + GTEx datasets, and tissue microarrays (TMAs) of 56 patients with LUAD from our hospital. …”
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165
Phenomenon of loss of heterozygosity in tumour tissue of breast cancer: association with expression of monoresistance genes
Published 2018-01-01“…DNA was extracted from 68 biopsy specimens of tumour tissues using QIAamp DNA mini Kit (Qiagen, Germany). LOH status was detected using microarray analysis using high density DNA-chip manufactured by Affymetrix CytoScanTM HD Array company.Results. …”
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Higher expression of mir‐31‐5p is associated with reduced risk of head and neck keloid recurrence following surgical resection
Published 2024-12-01“…Methods Using a tissue microarray, mir‐31‐5p expression was measured with miRNAscope, and mir‐31‐5p cell positivity was determined with QuPath. …”
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168
Dissection of a complex transcriptional response using genome‐wide transcriptional modelling
Published 2009-11-01“…We examined the transcriptional response to DNA damage in a human T cell line (MOLT4) using microarrays. By measuring both mRNA accumulation and degradation over a short time course, we were able to construct a mechanistic model of the transcriptional response. …”
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169
A novel multiple marker microarray analyzer and methodology to predict major obstetric syndromes using surface markers of circulating extracellular vesicles from maternal plasma
Published 2025-01-01“…Plasma samples were tested using a multiple microarray analyzer. Glass slides with 17 antibodies against EV surface receptors ‐ were incubated with raw plasma samples, detected by biotinylated secondary antibodies specific to EVs or placental EVs (PEVs), and labeled with cyanine 5–streptavidin. …”
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170
Genome-wide profiling of micro-RNA expression in gefitinib-resistant human lung adenocarcinoma using microarray for the identification of miR-149-5p modulation
Published 2017-03-01“…We compared the micro-RNA expression profiles of the HCC827 cells HCC827/GR-8-1 using Agilent micro-RNA microarrays. The micro-RNAs, such as the miR-149-5p, were up- or downregulated and associated with acquired gefitinib resistance. …”
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The Comparison of Three Measures in Feature Selection
Published 2018-02-01“…Three representative linear or nonlinear measures,linear correlation coefficient,symmetrical uncertainty,and mutual information are selected. By combining them with the fast correlation-based filter ( FCBF) feature selection method,we make the comparison of selected feature subset from 8 gene microarray and image datasets. …”
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QCanvas: An Advanced Tool for Data Clustering and Visualization of Genomics Data
Published 2012-12-01Get full text
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175
Tissue‐based quantitative proteomics to screen and identify the potential biomarkers for early recurrence/metastasis of esophageal squamous cell carcinoma
Published 2018-06-01“…Thirteen proteins were selected by cutoff value of 0.67 fold for underexpression and 1.5‐fold for overexpression. …”
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176
Investigation of local corrosion behavior and mechanism for TA2/HAl77-2/316L SS coupling systems under seawater liquid film
Published 2025-02-01“…Local corrosion parameters, such as the maximum potential difference (ΔEmax), the maximum anode current density (Ia,max), the local corrosion intensity factor (LCII), and the cathode to anode area ratio (Sc/Sa) were obtained to quantitatively characterize the local corrosion degree of microarray electrodes. The results showed that HAl77-2 and most of the 316L SS electrode wires in the microarray electrodes served as anodes, while TA2 and the remainder of the 316L SS electrode wires performed as cathodes. …”
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177
A cross-sectional pilot study to estimate the frequency of minor blood group alleles and phenotypes in RhD-negative North Indian blood donors by DNA microarray analysis
Published 2024-12-01“…Hence, we planned to estimate frequencies of blood group alleles/phenotypes using DNA microarray analysis in the north Indian RhD-negative blood donor population. …”
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178
Exome sequencing and prenatal skeletal abnormalities: comprehensive review and meta-analysis and way forward
Published 2025-06-01“…ObjectiveTo assess the detection rate of exome sequencing (ES) in fetuses diagnosed as skeletal abnormalities (SKA) with normal karyotype or chromosomal microarray analysis (CMA) results.MethodsWe conducted electronic searches in four databases, focusing on studies involving ES in fetuses with SKA. …”
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The Genetics of 241 Fetuses With Talipes Equinovarus: A 8‐Year Monocentric Retrospective Study
Published 2025-02-01“…ABSTRACT Objective This study aims to investigate the utility of chromosomal microarray analysis (CMA) and whole exome sequencing (WES) in fetuses diagnosed with talipes equinovarus (TE), as well as to explore the genetic factors contributing to TE. …”
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180
Unveiling a rare genetic aberration: A case study of Prader-Willi syndrome (PWS) with atypical 15q11.2-q13.3 deletion
Published 2025-05-01“…The present case report describes the chromosomal anomalies suspected to be present in a neonate, detected using Chromosomal Microarray analysis, an advanced platform for genetic analysis. …”
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