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621
Neighbourhood continuity is not required for correct testis gene expression in Drosophila.
Published 2010-11-01“…We compare gene expression in individuals carrying inverted chromosomes with their non-inverted but otherwise identical progenitors using whole-transcriptome microarray analysis, validating these data with specific quantitative real-time PCR assays. …”
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622
Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions.
Published 2016-12-01“…We evaluated here whether this compound could present a host cell-dependent mechanism of action. Microarray profiling of THP-1 macrophages treated with naloxonazine showed upregulation of vATPases, which was further linked to an increased volume of intracellular acidic vacuoles. …”
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623
Reprogramming‐derived gene cocktail increases cardiomyocyte proliferation for heart regeneration
Published 2016-12-01“…Several candidate genes were selected and tested for their ability to induce CM proliferation. …”
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624
Comparing gene-gene co-expression network approaches for the analysis of cell differentiation and specification on scRNAseq data
Published 2025-01-01“…Gene-gene co-expression network analysis has been widely applied to bulk RNA sequencing and microarray data to investigate different phenotypes and compound exposures. …”
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625
Herpes simplex virus type-1 infection and spread in a novel porcine corneal explant model is restricted to the epithelium.
Published 2025-05-01“…We infected these corneas topically via high-density microarray patches (HD-MAPs) dipped in GFP-labelled HSV-1. …”
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626
Sensitive and precise quantification of insulin-like mRNA expression in Caenorhabditis elegans.
Published 2011-03-01“…We validated the platform using 53 RNA samples previously characterized by high density oligonucleotide microarray analysis. For this set of genes and the standard nCounter protocol, sensitivity and precision were comparable between the two platforms. …”
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627
CHD1 contributes to intestinal resistance against infection by P. aeruginosa in Drosophila melanogaster.
Published 2012-01-01“…Evidence for a role as transcriptional regulator comes from its colocalization with elongating RNA polymerase II as well as from studies of fly Hsp70 transcription. Here we used microarray analysis to identify target genes of CHD1. …”
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628
Xirp proteins mark injured skeletal muscle in zebrafish.
Published 2012-01-01“…Through the use of Xirp1 and Xirp2a as markers, myocellular injury can now be detected, even though functional studies indicate that these proteins are not essential in this process. …”
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629
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630
Tissue-restricted expression of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles.
Published 2011-01-01“…Seven zebrafish genes (gstp1, mgst3b, prdx1, frrs1c, fthl, gclc and hmox1a) suitable for WISH analysis were selected from candidates for Nrf2 targets identified by microarray analysis. …”
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631
Inferring pathway activity toward precise disease classification.
Published 2008-11-01“…The advent of microarray technology has made it possible to classify disease states based on gene expression profiles of patients. …”
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632
The apoptotic and genomic studies on A549 cell line induced by silver nitrate
Published 2017-04-01“…The influences of silver nitrate were studied via MTT assay, flow cytometry, immunocytochemical, confocal and transmission electron microscopy, and microarray assays. Silver nitrate showed inhibitory effects against A549 cells in a dose- and time-dependent manner for 24, 48, and 72 h and induced apoptosis. …”
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633
Pain-stimulated ultrasound vocalizations and their impact on pain response in mice.
Published 2025-01-01“…We also examined the effects of psychological stress caused by the ultrasound on an inflammatory pain model of mice. …”
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634
Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors.
Published 2017-01-01“…All the enterolignans/precursors examined showed activation of the Erk1/2 and PI3K/Akt pathways, indicating the involvement of rapid signaling through the non-genomic estrogen signaling pathway. However, when their effects on specific cell functions, cell cycle progression and chemokine (MCP-1) secretion were examined, positive effects were observed only for enterolactone, suggesting that signals are given in certain directions at a position closer to cell functions. …”
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635
Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans.
Published 2012-01-01“…However, the mechanisms underlying these effects are incompletely understood. Using whole-genome microarray analysis, we identified transcripts whose levels are altered by mutations in the intraflagellar transport protein daf-10, which result in impaired development and function of many sensory neurons in C. elegans. …”
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636
Constitutional Chromothripsis on Chromosome 2: A Rare Case with Severe Presentation
Published 2024-01-01“…We concluded that the complexity of the genomic rearrangement and the combined dosage/structural effect of these copy number variants are likely explanations for the severe presentation in our patient.…”
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637
RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes
Published 2014-01-01“…We propose a novel method to measure and extract the reliable (biologically true or valid) interactions from gene interaction networks and incorporate the extracted reliable gene interactions into our proposed RRHGE algorithm to identify significant gene signatures from microarray gene expression data for classifying ER+ and ER− breast cancer samples. …”
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638
Integrated multiomics analysis identifies potential biomarkers and therapeutic targets for autophagy associated AKI to CKD transition
Published 2025-04-01“…We performed weighted correlation network analysis (WGCNA) using two microarray datasets (GSE139061 and GSE66494) in the GEO database and identified autophagy signatures by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), and GSEA enrichment analysis. …”
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639
Theory on the coupled stochastic dynamics of transcription and splice-site recognition.
Published 2012-01-01“…We evaluate these theoretical predictions by considering human and mouse exon microarray data as well as RNAseq data from multiple different tissues. …”
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640
Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease
Published 2016-01-01“…To investigate this, we developed a protein microarray system to detect multiple cytokines in small volumes of serum. …”
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