Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations by Dan Li, Jianying Li, Donald J. Johann, Daniel Butler, Guangchun Chen, Jonathan Foox, Binsheng Gong, Wendell Jones, David P. Kreil, Rebecca Kusko, Paweł P. Łabaj, Anne Bergstrom Lucas, Christopher E. Mason, Christopher Mozsary, Natalia Novoradovskaya, Carlos Pabón-Peña, Bohu Pan, Todd A. Richmond, Roberta Maestro, Sayed Mohammad Ebrahim Sahraeian, Andreas Scherer, Hagen U. Tilgner, James C. Willey, Pierre R. Bushel, Joshua Xu

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Enucleation-Induced Rat Adrenal Gland Regeneration: Expression Profile of Selected Genes Involved in Control of Adrenocortical Cell Proliferation by Marianna Tyczewska, Marcin Rucinski, Agnieszka Ziolkowska, Marta Szyszka, Marcin Trejter, Anna Hochol-Molenda, Krzysztof W. Nowak, Ludwik K. Malendowicz

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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. by Simon R Stockwell, Georgina Platt, S Elaine Barrie, Georgia Zoumpoulidou, Robert H Te Poele, G Wynne Aherne, Stuart C Wilson, Peter Sheldrake, Edward McDonald, Mathilde Venet, Christelle Soudy, Frédéric Elustondo, Laurent Rigoreau, Julian Blagg, Paul Workman, Michelle D Garrett, Sibylle Mittnacht

“…Our work therefore identifies CCT020312 as a novel small molecule chemical tool for the selective activation of EIF2A-mediated translation control with utility for proof-of-concept applications in EIF2A-centered therapeutic approaches, and as a chemical starting point for pathway selective agent development. …”
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Highlights on Novel Technologies for the Detection of Antibodies to Ro60, Ro52, and SS-B by M. Infantino, C. Bentow, A. Seaman, M. Benucci, F. Atzeni, P. Sarzi-Puttini, B. Olivito, F. Meacci, M. Manfredi, M. Mahler

“…Similar findings were obtained with QUANTRIX Microarray kit. Conclusion. QUANTA Flash and BioPlex 2200 show good qualitative agreement. …”
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Serum/glucose starvation enhances binding of miR-4745-5p and miR-6798-5p to HNRNPA1 mRNA 3ʹUTR: A novel method to identify miRNAs binding to mRNA 3ʹUTR using λN peptide-boxB sequen... by Tetsuyuki Takahashi, Mai Funamura, Shun Wakai, Takao Hijikata

“…Using the novel interaction between the λN peptide and boxB sequence (λN/boxB system) and miRNA microarray analysis, we aimed to identify specific-binding microRNAs (miRs or miRNAs) targeting HNRNPA1 mRNA 3ʹUTR under serum/glucose-starved conditions. …”
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Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production. by Matthew J Peirce, Matthew Brook, Nicholas Morrice, Robert Snelgrove, Shajna Begum, Alessandra Lanfrancotti, Clare Notley, Tracy Hussell, Andrew P Cope, Robin Wait

“…<h4>Background</h4>Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. …”
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Development and validation of a Luminex assay for detection of a predictive biomarker for PROSTVAC-VF therapy. by Julie L Lucas, Erin A Tacheny, Allison Ferris, Michelle Galusha, Apurva K Srivastava, Aniruddha Ganguly, P Mickey Williams, Michael C Sachs, Magdalena Thurin, James V Tricoli, Winnie Ricker, Jeffrey C Gildersleeve

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An Autocatalytic Platform Combining a Nonlinear Hybridization Chain Reaction and DNAzyme to Detect microRNA by Hongbo Zhang, Xiuen Cao, Qubo Zhu

“…Conventional methods for miRNA detection, such as quantitative PCR and microarray analysis, often entail intricate sample preparation and lack the requisite sensitivity to detect low-abundance miRNAs like miRNA-21. …”
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Specificities of multi-primer polymerase chain reaction optimization for the detection of infectious pneumonia agents in human by E. S. Klochikhina, V. E. Shershov, V. E. Kuznetsova, S. A. Lapa, A. V. Chudinov

“…A prototype of a system for pathogenic agent detection in the immobilized phase (biological microarray) was created.…”
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Research on Biological Detection Based on Reflected Light Images of a Porous Silicon Bragg Mirror by Shuangshuang Zhang, Miao Sun, Jianfeng Yang, Zhenhong Jia, Xiaoyi Lv, Xiaohui Huang

“…Based on this method, the DNA detection limit is 20.74&#x00A0;pM. The method is low-cost, has a short detection time and can be used in the detection of biosensor microarray.…”
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Prenatal genetic detection in foetus with gallbladder size anomalies: cohort study and systematic review of the literature by Yimo Zeng, Rong Hu, Jian Lu, Yiming Qi, Dan Chen, Chaoxiang Yang, Jing Wu

“…All these patients underwent chromosomal microarray and/or karyotyping, and 37 cases also underwent whole exome sequencing (WES). …”
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RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis by S. M. Nuruzzaman Nobel, S M Masfequier Rahman Swapno, Md. Ashraful Hossain, Mejdl Safran, Sultan Alfarhood, Md. Mohsin Kabir, M. F. Mridha

“…This study primarily uses a unique dataset painstakingly selected from 20 esteemed medical institutes. The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. …”
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Quantitative and Qualitative Variations in TILs in Risk Stratification and Patient Selection for Neoadjuvant Chemotherapy of the Luminal B and Triple-Negative Breast Cancer Immunop... by Ana Car Peterko, Koraljka Rajković Molek, Anita Savić Vuković, Tamara Gulić, Petra Valković Zujić, Eleonora Cini Tešar, Damir Juranić, Aleksandra Pirjavec Mahić, Franjo Lovasić, Gordana Đorđević, Manuela Avirović

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Clinical application of sparse canonical correlation analysis to detect genetic associations with cortical thickness in Alzheimer’s disease by Bo-Hyun Kim, Sang Won Seo, Sang Won Seo, Sang Won Seo, Yu Hyun Park, JiHyun Kim, Hee Jin Kim, Hee Jin Kim, Hee Jin Kim, Hyemin Jang, Hyemin Jang, Hyemin Jang, Hyemin Jang, Jihwan Yun, Jihwan Yun, Jihwan Yun, Jihwan Yun, Mansu Kim, Jun Pyo Kim, Jun Pyo Kim, Jun Pyo Kim

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EsoDetect: computational validation and algorithm development of a novel diagnostic and prognostic tool for dysplasia in Barrett’s esophagus by Migla Miskinyte, Benilde Pondeca, José B. Pereira-Leal, Joana Cardoso

“…Specifically, for the diagnostic application, three RNAseq datasets were employed, while for the prognostic application, nine microarray datasets were identified, and 25 previously described genes were validated. …”
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Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression by Larsson Omberg, Joel R Meyerson, Kayta Kobayashi, Lucy S Drury, John F X Diffley, Orly Alter

“…This confirms previous predictions from mathematical modeling of a global causal coordination between DNA replication origin activity and mRNA expression, and shows that mathematical modeling of DNA microarray data can be used to correctly predict previously unknown biological modes of regulation.…”
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Utilizing Machine Learning Techniques for Cancer Prediction and Classification based on Gene Expression Data by Mariwan Mahmood Hama Aziz, Sozan Abdullah Mahmood

“…Lately, several studies have delved into cancer classification by leveraging data mining techniques, machine learning algorithms, and statistical methods to thoroughly analyze high-dimensional datasets. Detecting cancer early by examining gene expression data is vital for providing effective patient care. …”
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Advances in Research on Isothermal Signal Amplification Mediated MicroRNA Detection of Clinical Samples: Application to Disease Diagnosis by Yu Han, Xin Sun, Sheng Cai

“…However, the intrinsic characteristics of miRNAs, including their low abundance, short sequence lengths, and high family-specific sequence homology, render traditional detection methods such as Northern blot hybridization, microarray use, and reverse transcription quantitative PCR (RT-qPCR) inadequate for meeting the stringent requirements of clinical detection in biological samples, a task requiring accuracy, rapidity, high detection power, specificity, and cost-effectiveness. …”
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Detection efficacy of non-invasive prenatal testing for copy number variations in the recurrent 17p12 region by ZHANG Lanlan, HAN Xu, LI Niu, WANG Jian, LI Shuyuan

“…Follow-up was conducted to assess the results of subsequent prenatal diagnosis and chromosomal microarray analysis (CMA) performed on peripheral blood from both the pregnant women and their husband. …”
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SVseq discloses the genomic complexity of different prenatal, de novo, apparently balanced chromosome rearrangements detected by CMA and karyotype by Shengfang Qin, Xueyan Wang, Chun Chen, Jin Wang, Zhuo Zhang, Yan Yin, Xiangyou Leng

“…Methods Five children with BCRs detected through karyotyping and chromosome microarray analysis (CMA) during prenatal diagnoses were analyzed using SVseq technology. …”
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