-
221
Using rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression data.
Published 2012-01-01“…A comparison with other benchmark microarray sample classifiers based on three diverse feature selection algorithms suggests that these evolutionary learning techniques can compete with state-of-the-art methods like support vector machines. …”
Get full text
Article -
222
Cysteine‐rich intestinal protein 1 enhances the progression of hepatocellular carcinoma via Ras signaling
Published 2022-01-01“…Further study showed that the overexpression of CRIP1 enhanced the proliferation and migration of HepG2 cells, but the inhibition of CRIP1 decreased the proliferation and migration of HepG2 cells. Microarray assays and KyotoEncyclopedia of Genes and Genomes (KEGG) pathway analysis showed that overexpression of CRIP1 induced the activation of Ras signaling. …”
Get full text
Article -
223
Exploration of the shared pathways and common biomarkers in cervical and ovarian cancer using integrated bioinformatics analysis
Published 2024-12-01“…Abstract Objective Searching for potential biomarkers and therapeutic targets for early diagnosis of gynecological tumors to improve patient survival. Methods Microarray datasets of cervical cancer (CC) and ovarian cancer (OC) were downloaded from the Gene Expression Omnibus (GEO) database, then, differential gene expression between cancerous and normal tissues in the datasets was analyzed. …”
Get full text
Article -
224
Evaluation of gene expression classification studies: factors associated with classification performance.
Published 2014-01-01“…The MAQC II study on cancer classification problems has found that performance was affected by factors such as the classification algorithm, cross validation method, number of genes, and gene selection method. In this paper, we study the hypothesis that the disease under study significantly determines which method is optimal, and that additionally sample size, class imbalance, type of medical question (diagnostic, prognostic or treatment response), and microarray platform are potentially influential. …”
Get full text
Article -
225
Investigating Single-Molecule Molecular Inversion Probes for Medium-Scale Targeted DNA Methylation Analysis
Published 2025-03-01“…Considering CpGs with at least 20X coverage, we yielded robust methylation detection with levels comparable to those obtained from the gold standard EPIC microarray analysis (Pearsons’s r: 0.96). …”
Get full text
Article -
226
Integrating single-cell RNA sequencing, WGCNA, and machine learning to identify key biomarkers in hepatocellular carcinoma
Published 2025-04-01“…Abstract The microarray and single-cell RNA-sequencing (scRNA-seq) datasets of hepatocellular carcinoma (HCC) were downloaded from the Gene Expression Omnibus (GEO) database. …”
Get full text
Article -
227
Identification of potential biomarkers for 2022 Mpox virus infection: a transcriptomic network analysis and machine learning approach
Published 2025-01-01“…This study aimed to identify the differentially expressed genes (DEGs) induced by the 2022 MPXV infection through comprehensive bioinformatics analyses of microarray and RNA-Seq datasets from post-infected cell types with different MPXV clades. …”
Get full text
Article -
228
Ultrasensitive Bead-Based Immunoassay for Real-Time Continuous Sample Flow Analysis
Published 2025-05-01“…The flow cell is integrated with a microarray-based signal detection module, where beads with bound analyte scan the microarray surface and are retained on it by single specific interactions, assuring ultra-high sensitivity of the method. …”
Get full text
Article -
229
Genetic correlation between fetal nuchal translucency thickening and cystic hygroma and exploration of pregnancy outcome
Published 2024-11-01“…Abstract Chromosome microarray analysis (CMA) and whole exome sequencing (WES) are increasingly utilized in prenatal diagnosis of abnormal ultrasound findings, but studies on correlation between pathogenic copy number variations (pCNVs) and single-gene mutations in fetuses with nuchal translucency (NT) thickening/cystic hygroma (CH), and pregnancy outcomes, are rare. …”
Get full text
Article -
230
Study on hsa_circ_101209 in Plasma of Pregnant Women with Deep Venous Thrombosis
Published 2025-01-01“…Sixty women with DVT were selected as the DVT group, and 60 women without DVT as the non-DVT group. hsa_circ_14797 in plasma was detected, as well as D-dimer (D-D) concentration and P-selectin expression. …”
Get full text
Article -
231
Bioinformatics meets machine learning: identifying circulating biomarkers for vitiligo across blood and tissues
Published 2025-05-01“…The merged microarray data were then used for WGCNA to identify modules of features genes. …”
Get full text
Article -
232
Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada.
Published 2020-01-01“…Multi-Locus Sequence Typing (MLST) and SCCmec typing revealed two profiles (ST398-MRSA-V and ST8-MRSA-IVa), which were distinct using pulse-field gel electrophoresis (PFGE) and microarray (antimicrobial resistance and virulence genes) analyses. …”
Get full text
Article -
233
A Synopsis of Serum Biomarkers in Cutaneous Melanoma Patients
Published 2012-01-01“…However, the poor sensitivity and specificity of those markers and many other molecules are serious limitations for their routine use in both early (AJCC stage I and II) and advanced stages of melanoma (AJCC stage III and IV). Microarray technology and proteomic research will surely provide new candidates in the near future allowing more accurate definition of the individual prognosis and prediction of the therapeutic outcome and select patients for early adjuvant strategies.…”
Get full text
Article -
234
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.
Published 2011-01-01“…In order to obtain a global view of the impact of Snail and Slug expression, we performed a microarray experiment using the MCF-7 breast cancer cell line, which does not express detectable levels of Snail or Slug. …”
Get full text
Article -
235
An Ensemble Classification Method for High-Dimensional Data Using Neighborhood Rough Set
Published 2021-01-01“…Efficient and effective sample classification and feature selection are challenging tasks due to high dimensionality and small sample size of microarray data. …”
Get full text
Article -
236
Ultrasensitive Peptide-Based Electrochemical Biosensor for Universal Diagnostic of Dengue
Published 2025-04-01“…An identified linear B-cell epitope (DENV/18) specific for DENV 1–4 serotypes recognized by IgG in patient sera was selected as a target molecule after a microarray of peptides using the SPOT-synthesis methodology. …”
Get full text
Article -
237
Cuproptosis-related signature and immune infiltration in age-related macular degeneration
Published 2025-09-01“…METHODS: The expression profiles of cuproptosis-related genes and immune signature in AMD based on the microarray dataset GSE29801 were analyzed. A total of 142 AMD samples were used to identify the cuproptosis-related differentially expressed genes (Cu-DEGs), together with the immune cell infiltration. …”
Get full text
Article -
238
Chlamydiaceae in wild, feral and domestic pigeons in Switzerland and insight into population dynamics by Chlamydia psittaci multilocus sequence typing.
Published 2019-01-01“…Subsequent species identification was performed by DNA-microarray assay, sequencing of a 16S rRNA gene fragment and a C. psittaci specific qPCR. …”
Get full text
Article -
239
An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas.
Published 2014-03-01“…Herein, we take advantage of recent advances in systems biology and longitudinal studies in schistosomiasis endemic areas in Brazil to pilot an immunomics approach to the discovery of schistosomiasis vaccine antigens. We selected mostly surface-derived proteins, produced them using an in vitro rapid translation system and then printed them to generate the first protein microarray for a multi-cellular pathogen. …”
Get full text
Article -
240
Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.
Published 2013-01-01“…Therefore, we studied chromosome 11 in a total of 813 samples from 773 individual patients with different myeloid malignancies by SNP microarrays and complemented the data with exome sequencing in selected cases exhibiting chromosome 11 defects. …”
Get full text
Article