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441
Association between a specific monocyte subset and heart failure with preserved ejection fraction in patients with uremia
Published 2025-01-01“…Conclusions: Specific gene detections can be an important early warning indicator and guide physicians in evaluating the risk of HFpEF in ESRD.…”
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442
TLR3 Plays Significant Roles against HBV-Associated HCC
Published 2015-01-01“…The apoptosis of tumor cells was also detected by TUNEL stain. Correlations between TLR3 expression and HBV infection, interstitial immunoreactive cells, and cells apoptosis in HCC were investigated. …”
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443
A long non-coding RNA lncRNA-PE promotes invasion and epithelial–mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway
Published 2017-05-01“…However, the detailed mechanisms underlying their activities are not fully understood. Using microarray technology, a number of long non-coding RNAs were previously identified to be aberrantly expressed in hepatocellular carcinoma. …”
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444
iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models.
Published 2013-01-01“…We defined a method to transform microarray data into graph representation that encodes miRNA and gene expression levels and the interactions between them as well. …”
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445
Upregulated Acute Systemic Inflammation-Related Genes based on Endotoxin Exposure Provide “Survival Benefit” or Create “High Risk of Death” in Leukaemia and Colon Cancer
Published 2024-12-01“…Using the R “Linear Models for Microarray Data” package, differentially expressed gene analyses were conducted to determine genes that differ between healthy and bacterial endotoxin-administered samples. …”
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446
Immortalized Human Schwann Cell Lines Derived From Tumors of Schwannomatosis Patients.
Published 2015-01-01“…Cell morphology was retained following multiple passaging and freeze/ thaw cycles. Gene expression microarray analysis was used to compare the cell lines with their respective parent tumors. …”
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447
Ubiquitin Specific Protease 26 (USP26) expression analysis in human testicular and extragonadal tissues indicates diverse action of USP26 in cell differentiation and tumorigenesis.
Published 2014-01-01“…Immunofluorescence colocalization studies were performed with formalin-fixed/paraffin-embedded and frozen tissues using primary and secondary antibodies to detect USP26 and AR protein expression. Human microarray dot blots were used to identify protein expression in extra-gonadal tissues. …”
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448
Molecular diagnosis of Usher syndrome: application of two different next generation sequencing-based procedures.
Published 2012-01-01“…We analyzed a total of 12 patients, most of which were negative for previously described mutations in known USH genes upon primer extension-based microarray genotyping. We enriched the NGS template either by whole exome capture or by Long-PCR of the known USH genes. …”
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449
Neutrophil Extracellular Traps Drive Kidney Stone Formation
Published 2025-01-01“… Introduction: This study aims to explore the contribution of neutrophil extracellular traps (NETs) to kidney stones. Methods: The microarray data from GSE73680 and bioinformatic analysis were applied to identify differentially expressed genes in patients with kidney stones. …”
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450
Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant ho...
Published 2014-01-01“…Here we present the first microarray study of transcriptional changes induced by the phloem-limited geminivirus TYLCSV infecting tomato, its natural host. …”
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451
Alternative splicing of NURF301 generates distinct NURF chromatin remodeling complexes with altered modified histone binding specificities.
Published 2009-07-01“…By comparing microarray expression profiles and phenotypes of null Nurf301 mutants with mutants that remove the C-terminal PHD fingers and bromodomain, we show that full-length NURF301 is not essential for correct expression of the majority of NURF gene targets in larvae. …”
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452
Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with porcine circovirus 2b.
Published 2014-01-01“…Furthermore, PCV2 has been detected in bone-marrow samples, potentially enabling an easy spread and reservoir for the virus. …”
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453
Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection.
Published 2010-01-01“…Thus, a comprehensive evaluation of the complex epithelial signaling to SARS-CoV is crucial for paving the way to better understand SARS pathogenesis. Based on microarray-based functional genomics, we report here the global gene response of 2B4 cells, a cloned bronchial epithelial cell line derived from Calu-3 cells. …”
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454
Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
Published 2015-01-01“…Total RNA was isolated and the gene expression profile was determined using DNA microarrays. Comparison of the microarray expression values with qRT-PCR analysis of selected genes validated the results. …”
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455
Evaluation of LRIG1 Expression in Larynx Pathologies
Published 2022-06-01“…Patients’ data were obtained from the medical records. The tissue microarray method was used to evaluate specimens. Results: There was a statistically significant difference between the tumor differentiation, diagnosis, and the expression of LRIG1 (respectively p=0.045, p<0.001). …”
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456
Common gene-network signature of different neurological disorders and their potential implications to neuroAIDS.
Published 2017-01-01“…An mRNA microarray analysis in HIV-infected monocytes showed significant changes in the expression of several genes of this in silico derived common pathway which suggests the possible physiological relevance of this gene-circuit in driving neuroAIDS condition. …”
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457
Investigation of Underlying Biological Association and Targets between Rejection of Renal Transplant and Renal Cancer
Published 2023-01-01“…Finally, the PLAC8 was selected for further research, including its clinical and biological role. …”
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458
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring.
Published 2008-04-01“…Endogenous expression of selected genes linked to the abnormally methylated CGIs was correspondingly decreased or increased by as much as 4-19-fold. …”
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459
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.
Published 2010-08-01“…Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer. …”
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460
Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.
Published 2008-02-01“…Pre-treatment of rats with a selective inhibitor of Stat3, T40214, reduced the IL-6-mediated increase in cardiac Stat3 activity, blocked successful resuscitation by IL-6 and reversed IL-6-mediated protection from cardiac apoptosis. …”
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