ARHGAP42 promotes cell migration and invasion involving PI3K/Akt signaling pathway in nasopharyngeal carcinoma by Qian Hu, Xiao Lin, Linxiaoxiao Ding, Yinduo Zeng, Danmei Pang, Nengtai Ouyang, Yanqun Xiang, Herui Yao

“…Western blot and immunohistochemical staining were used for detecting the expression of ARHGAP42 protein in nasopharyngeal carcinoma tissues and cell lines. …”
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Expression and prognostic significance of MLH1 and GPRC5C in resectable hepatocellular carcinoma by Jun Lu, Lei Li, Qing Chen, Bingqi Li, Siqian Ren, Meng Yuan, Meng Meng, Jian Lei, Yuntao Bing, Hangyan Wang, Zhaolai Ma, Dianrong Xiu, Chunhui Yuan

“…However, their expression and prognostic significance in hepatocellular carcinoma (HCC) has not been elucidated, especially for GPRC5C. Methods We detected MLH1 and GPRC5C expression using the tissue microarray-based immunohistochemical staining in tumor and matched adjacent non-tumor liver (ANL) specimens from 230 patients who underwent radical resection for HCC. …”
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Overexpression of cyclin‐dependent kinase 1 in esophageal squamous cell carcinoma and its clinical significance by Han‐Jie Zhang, Gang Chen, Shang‐Wei Chen, Zong‐Wang Fu, Hua‐Fu Zhou, Zhen‐Bo Feng, Jun‐Xian Mo, Chang‐Bo Li, Jun Liu

“…Microarray and external RNA‐seq data from 664 cases of ESCC and 1733 cases of control tissues were used to verify the difference in CDK1 expression between the two groups. …”
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Analysis of gene expression difference and biological process in chorionic villi of unexplained recurrent spontaneous abortion by Linling Shi, Lun Wei, Meiqiu Lu, Hongmei Ding, Le Bo

“…Abstract Objective To explore the biological relationship between the regulatory signal pathways involved in differentially expressed genes and recurrent spontaneous abortion (RSA) by analyzing the gene expression microarray data of unexplained RSA. Methods The gene expression profile data of chorionic villi from unexplained recurrent abortion with normal karyotype and selective induced abortion were compared. …”
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Maternal plasma cell-free DNA nucleosome footprints can reveal changes in gene expression profiles during pregnancy and pre-eclampsia by Kun Li, Zhiwei Guo, Fenxia Li, Shijing Lu, Min Zhang, Xingyu Wei, Chao Sheng, Wenbo Hao, Xuexi Yang

“…These results are consistent with prior microarray and RNA-sequencing data. Conclusions The depth of the cfDNA nucleosome footprint in maternal plasma can be used to reflect changes in the gene expression profile during pregnancy and pre-eclampsia. …”
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Does Bilirubin Have a Causal Relationship With Vitiligo? A Mendelian Randomization Study and Bioinformatics Analysis by Xu D, Yin Y, Teng Y, Huang Y, Yu Y, Tao X, Fan Y, Ding X

“…This study aims to investigate the causal associations between bilirubin and vitiligo using Mendelian randomization (MR) analysis, complemented by bioinformatics validation to unravel the underlying molecular mechanisms.Methods: Genome-wide association study (GWAS) data pertaining to vitiligo and bilirubin were obtained, followed by the execution of a bidirectional MR analysis. Additionally, we performed a bioinformatics analysis using microarray datasets to identify differentially expressed genes (DEGs) in relation to bilirubin in patients with vitiligo. …”
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Mechanism of immune escape mediated by receptor tyrosine kinase KIT in thyroid cancer by Zhen Luo, Jin Xu, Dayong Xu, Jiaojiao Xu, Rongjun Zhou, Keping Deng, Zheng Chen, Fang Zou, Libo Yao, Yuqin Hu

“…Methods The expression microarray of TC was acquired through the GEO database, and the difference analysis and Kyoto encyclopedia of genes and genomes pathway enrichment analysis were carried out. …”
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Characterizing Methicillin-Resistant <i>Staphylococcus</i> spp. and Extended-Spectrum Cephalosporin-Resistant <i>Escherichia coli</i> in Cattle by Lisa Abdank, Igor Loncaric, Sascha D. Braun, Elke Müller, Stefan Monecke, Ralf Ehricht, Reinhild Krametter-Frötscher

“…Twenty-two <i>Escherichia coli</i> isolates were detected among the fecal samples. All the <i>Escherichia coli</i> isolates were resistant to ceftazidime. …”
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Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine by Wenjing Feng, Mengwei Ju, Tao Wang, Shanshan Cui, Kexin Yang, Zhiting Guo, Miao Liu, Jiaxuan Tao, Huiyan Yu, Rong Xiao

“…Methods Liquid chromatography-mass spectrometry, untargeted metabolomic analysis, and m6A mRNA Epitranscriptomic Microarray were used to detect the characteristics of serum oxysterols (n = 35/group), fecal gut metabolites (n = 30/group), and m6A in whole blood (n = 4/group) respectively. …”
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Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects by Louise Kaldjob-Heinrich, Sandro Nuciforo, Steffen Lemke, Aaron Stahl, Stefan Czemmel, Sepideh Babaei, Lauriane Blukacz, Marie-Anne Meier, Yizheng Zhang, Christian M. Schürch, Irene Gonzalez-Menendez, Pascal Woelffing, Nisar P. Malek, Veit Scheble, Sven Nahnsen, Manfred Claassen, Markus Templin, Hans Bösmüller, Markus H. Heim, Daniel Dauch, Michael Bitzer

“…Methods: Patient-derived tissue microarrays and RNA-sequencing were employed to investigate ADORA3 expression. …”
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Associations between pathophysiological traits and symptom development in retrospective analysis of V30M and V122I transthyretin amyloidosis by Sameer U. Kini, Ha My Thi Vy, Madhav Subramanian, Parasuram M. Krishnamoorthy, Son Q. Duong, Ghislain Rocheleau, Jagat Narula, Ron Do, Girish N. Nadkarni

“…This retrospective analysis of microarray and biobank data helped establish clinical biomarkers for early hATTR detection. …”
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Radiation suppresses liver metastases via exosome secretion in pancreatic cancer cells by Ai Nakaoka, Mohammed Salah, Zhangzhu Ruixian, Makiko Nakahana, Yasuyuki Shimizu, Qin Qin, Qu Zhang, Naritoshi Mukumoto, Kana Kobayashi, Yukihiro Ikegaki, Hiroaki Akasaka, Sachiko Inubushi, Yu-ichiro Koma, Takeaki Ishihara, Daisuke Miyawaki, Takashi Sasayama, Ryohei Sasaki

“…Additionally, IR-Exos prevented liver metastasis induced by MIAPaCa-2 cells in vivo We detected 2,565 miRNAs in exosomes in a microarray. …”
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Impact of B7-H3 expression on metastasis, immune exhaustion and JAK/STAT and PI3K/AKT pathways in clear cell renal cell carcinoma by Maite Emaldi, Esther Rey-Iborra, Ángela Marín, Lorena Mosteiro, David Lecumberri, Tove Øyjord, Noémie Roncier, Gunhild M. Mælandsmo, Javier C. Angulo, Peio Errarte, Gorka Larrinaga, Rafael Pulido, José I. López, Caroline E. Nunes-Xavier

“…However, many treated patients do not respond, making novel immune checkpoint-based immunotherapies potentially clinically beneficial only for specific groups of patients. We detected high expression of the immune checkpoint protein B7-H3 in clear cell renal cell carcinomas (ccRCCs) and evaluated B7-H3 immunohistochemistry staining in tissue microarray samples from two distinct renal cancer cohorts. …”
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Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression by Fangjian Shang, Hongfeng Nie, Liyan Du, Jin Shang, Xiangquan Song, Ya Chen, Hui Li, Zhuo Wang, Yixin Qi, Liyan Zhao

“…Methods TNBC-related datasets were retrieved from The Cancer Genome Atlas and selected by Prediction Analysis of Microarray 50 analysis to assess the expression of PMAIP1 in the samples. …”
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DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer. by Steven T Lott, Nanyue Chen, Dawn S Chandler, Qifeng Yang, Luo Wang, Marivonne Rodriguez, Hongyan Xie, Seetharaman Balasenthil, Thomas A Buchholz, Aysegul A Sahin, Katrina Chaung, Baili Zhang, Shodimu-Emmanu Olufemi, Jinyun Chen, Henry Adams, Vimla Band, Adel K El-Naggar, Marsha L Frazier, Khandan Keyomarsi, Kelly K Hunt, Subrata Sen, Bruce Haffty, Stephen M Hewitt, Ralf Krahe, Ann McNeill Killary

“…<h4>Background</h4>Breast cancer in young women tends to have a natural history of aggressive disease for which rates of recurrence are higher than in breast cancers detected later in life. Little is known about the genetic pathways that underlie early-onset breast cancer. …”
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Expression, clinical significance and biological function of CDC7 in osteosarcoma by CHEN Peijun, MAN Yunan, HE Mingwei, LIANG Bumin, HE Maolin

“…Immunohistochemistry (IHC) was used to detect the expression of CDC7 protein in 39 cases of OS tissues and 8 cases of adjacent normal tissues. …”
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Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…In patient 1, pedigree analysis, CGH and SNP 4 × 180 K microarray testing identified paternal uniparental diploidy (c.301C > T/11q12.3-11q25del) [upd (11) pat] on chromosome 11. …”
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Unique reporter-based sensor platforms to monitor signalling in cells. by Meesbah Jiwaji, Rónán Daly, Abdullah Gibriel, Gráinne Barkess, Pauline McLean, Jingli Yang, Kshama Pansare, Sarah Cumming, Alisha McLauchlan, Piotr J Kamola, Musab S Bhutta, Adam G West, Katherine L West, Walter Kolch, Mark A Girolami, Andrew R Pitt

“…The methodology uses two robust and easily accessible detection platforms; quantitative real-time PCR for quantitative analysis and DNA microarrays for parallel, higher throughput analysis.…”
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Molecular mechanism and biological pathway of high-expressed RAD51 in regulating cell adhesion and potentially affecting oral squamous cell carcinoma by Yu-Xing Tang, Yu-Yan Pang, Yan Cui, Guo-Jiao Wu, Lin-Qing Huang, Chang-Zhan Zhou, Bin Li, Qi Li, Bang-Teng Chi, Rong-Quan He, Di-Yuan Qin, Jian-Di Li, Gang Chen, Dong-Ming Li, Yi-Wu Dang

“…Abstract Background Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the oral cavity, with over 70% of cases detected in advanced stages and a 5-year survival rate of 50%. …”
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Acetylation suppresses breast cancer progression by sustaining CLYBL stability by Xinyue Deng, Chenglong Ma, Xingyu Chen, Ming Yi, Qianhua Cao, Ruocen Liao, Xingyu Lei, Longchang Bai, Bin Zhao, Yingnan Wang, Zhuoyang Shen, Liujing Wu, Chenfang Dong, Zhijun Dai

“…Methods CLYBL expression patterns in breast cancer were assessed using a breast cancer tissue microarray, immunohistochemistry, and publicly available datasets. …”
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