The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo by Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei zhang

“…Pathological damage and apoptosis were detected in the DG, CA3, and CA1 regions of the hippocampus, along with the cortical area. …”
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Integrative in Silico and in vitro validation suggest LINC00963 and SNHG15 as candidate biomarkers for coronary artery disease by Mohammadreza Saberiyan, Parisa Noorabadi, Ozra Kahourian, Ahmad Golestanifar, Negar Jafari, Venus Shahabi Rabori, Pegah Mousavi

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Exposing Optimal Feature Sets for Enhancing Machine Learning Performance by Hiba Mohammed Al-Marwai, Ghaleb H. Al-Gaphari, Mohammed Mohammed Zayed

“…To evaluate the effectiveness of our approach, we conduct experiments on benchmark microarray datasets from the ADNI database. Comparative analysis is performed against six traditional single objective methods and five other existing multiobjective methods. …”
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Successful strategy of comprehensive pre-implantation genetic testing for Duchenne muscular dystrophy and chromosome balance using karyomapping and fluorescent PCR by Suchada Mongkolchaipak, Sirivipa Piyamongkol, Chutithep Teekaput, Rungthiwa Sirapat, Wanwisa Suriya, Tawiwan Pantasri, Theera Tongsong, Wirawit Piyamongkol

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Identification of three small nucleolar RNAs (snoRNAs) as potential prognostic markers in diffuse large B‐cell lymphoma by Mei‐wei Li, Feng‐xiang Huang, Zu‐cheng Xie, Hao‐yuan Hong, Qing‐yuan Xu, Zhi‐gang Peng

“…Results Twelve prognosis‐correlated snoRNAs were selected from the DLBCL patient cohort of microarray profiles, and a three‐snoRNA signature consisting of SNORD1A, SNORA60, and SNORA66 was constructed. …”
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Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella by Arlo Z. Randall, Valentino Conti, Usman Nakakana, Xiaowu Liang, Andy A. Teng, Antonio Lorenzo Di Pasquale, Melissa Kapulu, Robert Frenck, Odile Launay, Pietro Ferruzzi, Antonella Silvia Sciré, Elisa Marchetti, Christina Obiero, Jozelyn V. Pablo, Joshua Edgar, Philip Bejon, Adam D. Shandling, Joseph J. Campo, Angela Yee, Laura B. Martin, Audino Podda, Francesca Micoli

“…An ideal vaccine would provide protection against the most prevalent species, Shigella flexneri and Shigella sonnei; therefore, it could be relevant to identify common antigens. We developed a microarray containing 3,150 full-length or fragmented proteins selected across Shigella species. …”
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First African case report of hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome due to inverted duplication and deletion of chromosome 10p by Tumelo M. Satekge, Glenrose Rikhotso, Bianca Rossouw, Bronwyn Dillon, Fiona Baine-Savanhu

“…Here, we report the first African case of HDR syndrome to be confirmed by chromosomal microarray analysis (CMA). Case presentation A 3-month-old female presented with focal seizures due to severe hypocalcaemia associated with low parathyroid hormone. …”
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Case Report: Prenatal diagnosis of novel compound heterozygous variants in WDR35 gene causing short-rib thoracic dysplasia 7 with or without polydactyly by Jianlong Zhuang, Junyu Wang, Zhengping Huang, Yu’e Chen, Chunnuan Chen

“…In this article, we report a novel deletion compound combined with a causative variant in WDR35 gene leading to short-rib thoracic dysplasia 7 (SRTD7) with or without polydactyly using WES.MethodsThis study involved a Chinese fetus with clinical features of skeletal dysplasia on ultrasound imaging, in whom chromosome abnormalities and copy number variants (CNVs) were detected by chromosomal microarray analysis (CMA), and sequence variants were detected by WES. …”
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Serum profiling of the antibody response to HPV in women with or without abnormal cervical cytology undergoing cervical cancer screening by Radwa Ewaisha, Mack T. Ruffin, Stacy Williams, Yunro Chung, Yunro Chung, Cecilia R. DeGraffinreid, Electra D. Paskett, Electra D. Paskett, Paul L. Reiter, Ji Qiu, Dean E. Brenner, Karen S. Anderson

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INTEGRAL ANALYSIS OF GENOMIC AND TRANSCRIPTOMIC CHANGES IN CLEAR CELL RENAL CELL CARCINOMA IN THE RUSSIAN POPULATION by S. A. Solodskikh, A. V. Panevina, A. G. Novikova, J. D. Dvoretskaya, M. V. Gryaznova, A. A. Starkov, A. Yu. Maslov, A. A. Mikhailov, K. Khinolupos, V. N. Popov

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RESPONSE TO NEOADYAVANT CHEMOTHERAPY WITH PLATINUM-BASED DRUGS IN BREAST CANCER PATIENTS WITH BRCA1 DELETION IN TUMOR by M. M. Tsyganov, N. A. Tarabanovskaya, I. V. Deryusheva, M. K. Ibragimova, P. V. Kazantseva, A. M. Pevzner, E. M. Slonimskaya, N. V. Litviakov

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Identification of potential biomarkers and pathways related to major depressive disorder by integrated bioinformatic analysis and experimental validation by Ying Zeng, Lu-Qi Peng, Mei Zhang, Rong Zhong, Ke-Chao Nie, Wei Huang

“…Objective: To identify promising biomarkers for the pathogenesis of major depressive disorder (MDD). Methods: Microarray chips of MDD patients, including the GSE98793, GSE52790, and GSE39653 datasets, were obtained from the Gene Expression Omnibus database. …”
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Human Blood Autoantibodies in the Detection of Colorectal Cancer. by Ola H Negm, Mohamed R Hamed, Robert E Schoen, Richard L Whelan, Robert J Steele, John Scholefield, Elizabeth M Dilnot, H M C Shantha Kumara, John F R Robertson, Herbert F Sewell

“…We identified an antigen panel of sufficient sensitivity and specificity for early detection of CRC, based upon serum profiling of autoantibody response using a robust multiplex antigen microarray technology. …”
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Genetic etiology and pregnancy outcomes of fetal hyperechoic kidneys: a retrospective analysis by Meiying Cai, Na Lin, Ziheng Xiao, Ziheng Xiao, Hailong Huang, Lin Zheng, Liangpu Xu

“…Chromosome karyotyping and chromosomal microarray analysis (CMA) were performed on fetuses displaying this phenotype on prenatal ultrasound. …”
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Ultrasound and genetic findings in a case series of fetuses presenting vertebral defects by Wanqin Xie, Lin Zhou, Ai Hu, Jing Chen, Jialun Pang, Hui Xi, Yingchun Luo, Jiancheng Hu, Shuting Yang, Xiaoyang Gao, Hanzhe Kuang, Wanglan Tang, Rui Liu, Silong Wang, Ying Peng

“…Methods Fetuses with vertebral anomalies by a second or third trimester ultrasound screening between January 2020 and April 2024 at a single center were included in the study. Chromosome microarray analysis (CMA) as a first-line diagnostic test was performed. …”
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Possible cross‑talk between atrial fibrillation and obstructive sleep apnea revealed by transcriptomic analysis by Xinmiao Chen, Yi Li, Yao Liu

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A Ratiometric Fluorescent Detection Platform Using G‐CDs@[Ru(bpy)3]2+ for the Specific Detection of Hypochlorite and Live Cell Imaging by Mingcong Rong, Zheng He, Danru Wang, Jiahao Zeng, Qian Liu, Li Niu

“…In this work, a sensing platform for rapid, sensitive, and specific ClO− detection is constructed using green fluorescent carbon dots (G‐CDs), with a linear detection range of 0.5–11 µm and a detection limit of 0.233 µm. …”
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Evaluation of the HumanMethylationEPIC v2.0 Bead Chip Using Low Quality and Quantity DNA Samples by Brando Poggiali, Mikkel Eriksen Dupont, Marie-Louise Kampmann, Athina Vidaki, Vania Pereira, Claus Børsting, Jacob Tfelt-Hansen, Jeppe Dyrberg Andersen

“…Abstract Background The HumanMethylationEPIC v2.0 BeadChip (EPIC v2.0) microarray is a widely used tool for genome-wide DNA methylation (DNAm) analysis, designed for high-quality human DNA with a recommended input of 250 ng. …”
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Protein detection enhanced by 3DNA dendrimer signal amplification by Johanna R. Mora, Tamara L. Zielinski, Bryce P. Nelson, Robert C. Getts

“…DNA dendrimers, conjugated with both anti-biotin antibodies and up to 350 labeling entities, were designed and adapted to protein microarray and enzyme-linked immunosorbent assay (ELISA) to improve the limits of protein detection with no additional steps or equipment. …”
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Case Report: Optical genome mapping enables identification of complex balanced chromosomal rearrangements by Xiaohang Hu, Jing Guo, Haiyang Sang, Jinyan Yan, Hong Chang, Ting Liu, Haixin Dong, Min Kong, Yanjun Tian, Liqing Jiang

“…Peripheral blood samples were collected for high-resolution karyotyping, chromosomal microarray analysis, and optical genome mapping. The high-resolution karyotype analysis identified complex chromosomal abnormalities. …”
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