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401
CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma
Published 2025-04-01“…Mice bearing pulmonary OS metastases underwent alloBMT and alloNK cell infusion with anti-CD155 either before or after tumor induction, with select groups receiving anti-DNAM-1 pretreated alloNK cells. …”
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402
Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver
Published 2010-01-01“…Several studies have been conducted using PCR analysis and microarray technology to identify possible target genes and here we review the data obtained from various in vivo and in vitro experimental models. …”
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403
Herpes simplex virus type-1 infection and spread in a novel porcine corneal explant model is restricted to the epithelium.
Published 2025-05-01“…We infected these corneas topically via high-density microarray patches (HD-MAPs) dipped in GFP-labelled HSV-1. …”
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404
Lack of effect of the Salmonella deubiquitinase SseL on the NF-κB pathway.
Published 2013-01-01“…To attempt to clarify these discrepancies, we compared mRNA levels in mouse primary bone marrow-derived macrophages infected with wild-type or sseL mutant strains using a genome-wide microarray. There was no detectable effect of loss of SseL on mRNA levels corresponding to any known NF-κB-regulated gene. …”
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405
Sensitive and precise quantification of insulin-like mRNA expression in Caenorhabditis elegans.
Published 2011-03-01“…We validated the platform using 53 RNA samples previously characterized by high density oligonucleotide microarray analysis. For this set of genes and the standard nCounter protocol, sensitivity and precision were comparable between the two platforms. …”
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406
CHD1 contributes to intestinal resistance against infection by P. aeruginosa in Drosophila melanogaster.
Published 2012-01-01“…Evidence for a role as transcriptional regulator comes from its colocalization with elongating RNA polymerase II as well as from studies of fly Hsp70 transcription. Here we used microarray analysis to identify target genes of CHD1. …”
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407
Xirp proteins mark injured skeletal muscle in zebrafish.
Published 2012-01-01“…Through the use of Xirp1 and Xirp2a as markers, myocellular injury can now be detected, even though functional studies indicate that these proteins are not essential in this process. …”
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408
Bioinformatic identification of Single Nucleotide Polymorphisms (SNPs) in keratin-associated protein genes in alpacas (Vicugna pacos)
Published 2024-03-01“…Of these, 35 SNPs were included in the 76K alpaca SNP microarray and 32 SNPs were confirmed in a population of 936 alpacas.…”
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409
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
Published 2012-07-01“…We measured mRNA and protein levels in manipulated cells by microarray, RT–PCR and western blot analysis, respectively. …”
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410
Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression
Published 2008-02-01“…We used RNAi and time series, whole‐genome microarray analyses to systematically perturb and characterize components of a Caenorhabditis elegans lineage‐specific transcriptional regulatory network. …”
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411
Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
Published 2015-01-01“…Total RNA was isolated and the gene expression profile was determined using DNA microarrays. Comparison of the microarray expression values with qRT-PCR analysis of selected genes validated the results. …”
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412
Evaluation of LRIG1 Expression in Larynx Pathologies
Published 2022-06-01“…Patients’ data were obtained from the medical records. The tissue microarray method was used to evaluate specimens. Results: There was a statistically significant difference between the tumor differentiation, diagnosis, and the expression of LRIG1 (respectively p=0.045, p<0.001). …”
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413
Interpretable graph Kolmogorov–Arnold networks for multi-cancer classification and biomarker identification using multi-omics data
Published 2025-07-01“…The proposed approach combines differential gene expression with DESeq2, Linear Models for Microarray (LIMMA), and Least Absolute Shrinkage and Selection Operator (LASSO) regression to reduce multi-omics data dimensionality while preserving relevant biological features. …”
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414
MOLECULAR AND GENETIC INSIGHTS OF ROOT-KNOT NEMATODES PATHOGENICITY: A REVIEW
Published 2024-04-01“…Protein analysis and molecular databases help identify down-regulated and up-regulated genes. Microarray technology can provide large-scale gene expression data on plant-nematode interaction, aiding in understanding nematode selection and feeding site alteration, thereby identifying genes controlling cell differentiation and division. …”
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415
Common gene-network signature of different neurological disorders and their potential implications to neuroAIDS.
Published 2017-01-01“…An mRNA microarray analysis in HIV-infected monocytes showed significant changes in the expression of several genes of this in silico derived common pathway which suggests the possible physiological relevance of this gene-circuit in driving neuroAIDS condition. …”
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416
Investigation of Underlying Biological Association and Targets between Rejection of Renal Transplant and Renal Cancer
Published 2023-01-01“…Finally, the PLAC8 was selected for further research, including its clinical and biological role. …”
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417
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring.
Published 2008-04-01“…Endogenous expression of selected genes linked to the abnormally methylated CGIs was correspondingly decreased or increased by as much as 4-19-fold. …”
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418
Analytic approaches to clinical validation of results from preclinical models of glioblastoma: A systematic review.
Published 2022-01-01“…In 14 studies published between 2017 and 2020 using TCGA RNA microarray data that should have the same cohort, the median number of patients was 464.5 (interquartile range 220.5-525). …”
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419
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.
Published 2010-08-01“…Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer. …”
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420
Polymorphisms in the mitochondrial DNA control region and frailty in older adults.
Published 2010-06-01“…At baseline, frailty was identified as the presence of three or more of five indicators (weakness, slowness, shrinking, low physical activity, and exhaustion). mtDNA variation was assessed in a pilot study, including 315 individuals selected as extremes of the frailty phenotype, using an oligonucleotide sequencing microarray based on the Revised Cambridge Reference Sequence. …”
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